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Fibroblast growth factor receptor substrate

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Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

Below are the list of possible Fibroblast growth factor receptor substrate products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Fibroblast growth factor receptor substrate 2

 Fibroblast growth factor receptor substrate 2 ELISA Kit
 Fibroblast growth factor receptor substrate 2 Recombinant
 Fibroblast growth factor receptor substrate 2 Antibody
Also known as Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (FGFR-signaling adaptor SNT) (FRS2-alpha) (Suc1-associated neurotrophic factor target 1) (SNT-1).
FRS2: an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways.

Protein type: A
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daptor/scaffold

Cellular Component: cytoplasm; intercellular junction; plasma membrane

Molecular Function: fibroblast growth factor receptor binding; neurotrophin TRKA receptor binding; protein binding; transmembrane receptor protein tyrosine kinase adaptor protein activity

Biological Process: activation of MAPK activity; determination of anterior/posterior axis, embryo; fibroblast growth factor receptor signaling pathway; forebrain development; gastrulation with mouth forming second; induction of an organ; lens development in camera-type eye; neuroblast proliferation; optic placode formation involved in camera-type eye; regulation of apoptosis; regulation of epithelial cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway
 Frs2 ELISA Kit
 Frs2 Recombinant
 Frs2 Antibody
 Frs2a ELISA Kit
 Frs2a Recombinant
 Frs2a Antibody
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Fibroblast growth factor receptor substrate 3

 Fibroblast growth factor receptor substrate 3 ELISA Kit
 Fibroblast growth factor receptor substrate 3 Recombinant
 Fibroblast growth factor receptor substrate 3 Antibody
Also known as Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FGFR-signaling adaptor SNT2) (Suc1-associated neurotrophic factor target 2) (SNT-2).
FRS3: Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of E
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RK2.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: plasma membrane

Molecular Function: fibroblast growth factor receptor binding; identical protein binding; protein binding; Ras guanyl-nucleotide exchange factor activity

Biological Process: fibroblast growth factor receptor signaling pathway; MAPKKK cascade; signal transduction
 FRS3 ELISA Kit
 FRS3 Recombinant
 FRS3 Antibody
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