Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Protein Family  rightarrow Folliculin  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Connexin 40 (CX40) ELISA Kit
 • Protein bassoon (BSN) ELISA Kit
 • R-phycoerythrin gamma chain, chloroplastic Recombinant Protein
 • IRGM Antibody
 • Translocated actin-recruiting phosphoprotein (tarP), partial... Recombinant Protein
 • CCKBR - Cckb Antibody
 • UDP glycosyltransferase 8 (UGT8) ELISA Kit
 • Monoamine Oxidase A (MAOA) ELISA Kit
 • LEP ELISA Kit
 • Swine Anti-Rabbit IgG (H+L), Human-Rat-Mouse-Goat SP ads Secondary Antibody
 • EGTA Biochemical
 • ADAMTS2 siRNA
 • SDF-1-CXCL12 ELISA Kit
 • A Disintegrin And Metalloprotease 12 (ADAM12) ELISA Kit
 downarrow more ...
separator

Folliculin

separator
May be a tumor suppressor. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.

Below are the list of possible Folliculin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Folliculin

 Folliculin ELISA Kit
 Folliculin Recombinant
 Folliculin Antibody
FLCN: a protein that is expressed in most tissues and that has no significant homology to other proteins. Involved in nutrient sensing through the AMPK and mTOR signaling pathways. Regulates lysosome function by promoting the mTORC1-dependent sequestration of transcription factor EB (TFEB). Required for the recruitment of mTORC1 to lysosomes by Rag GTPases. Amino acid depletion leads to its recrui
>>>
tment to the surface of lysosomes where it directly binds RagA, an interaction that is promoted by FNIP1. May be a tumor suppressor. Loss of function mutations cause Birt-Hogg-Dube syndrome (BHD), a disease characterized by fibrofolliculomas (hair follicle tumors), and predispositions for renal carcinoma, pneumothorax, and pulmonary cysts. These symptoms are similar to those that occur in TSC or tuberous sclerosis complex, suggesting the involvement in the same pathways as TSC1. Belongs to the folliculin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Tumor suppressor

Cellular Component: cytoplasm; midbody; nucleus; plasma membrane

Molecular Function: protein complex binding

Biological Process: hemopoiesis; in utero embryonic development; intercellular junction assembly; negative regulation of cell growth; negative regulation of cell migration; negative regulation of protein kinase B signaling cascade; negative regulation of Rho protein signal transduction; negative regulation of TOR signaling pathway; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of autophagy; positive regulation of cell adhesion; positive regulation of protein amino acid phosphorylation; positive regulation of TOR signaling pathway; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transforming growth factor beta receptor signaling pathway; regulation of cytokinesis; regulation of histone acetylation; regulation of protein amino acid phosphorylation; regulation of TOR signaling pathway; TOR signaling pathway
 Flcn ELISA Kit
 Flcn Recombinant
 Flcn Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions