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Forkhead box protein

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Probable transcription factor.

Below are the list of possible Forkhead box protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Forkhead box protein A1

 Forkhead box protein A1 ELISA Kit
 Forkhead box protein A1 Recombinant
 Forkhead box protein A1 Antibody
Also known as Forkhead box protein A1 (FoxA1) (tFoxA1).
Probable transcription factor.
 foxa1 ELISA Kit
 foxa1 Recombinant
 foxa1 Antibody
Table BarTOPTable Bar
 

Forkhead box protein A1-A

 Forkhead box protein A1-A ELISA Kit
 Forkhead box protein A1-A Recombinant
 Forkhead box protein A1-A Antibody
Also known as Forkhead box protein A1-A (FoxA1a) (Fork head domain-related protein 7) (xFD-7) (Hepatocyte nuclear factor 3-alpha homolog A) (HNF3alpha homolog A) (xHNF3alpha-A).
Probable transcription factor.
 foxa1-a ELISA Kit
 foxa1-a Recombinant
 foxa1-a Antibody
 hnf-3a ELISA Kit
 hnf-3a Recombinant
 hnf-3a Antibody
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Forkhead box protein A1-B

 Forkhead box protein A1-B ELISA Kit
 Forkhead box protein A1-B Recombinant
 Forkhead box protein A1-B Antibody
Also known as Forkhead box protein A1-B (FoxA1b) (Fork head domain-related protein 7') (xFD-7') (Forkhead protein 2) (FKH-2) (xFKH2) (Hepatocyte nuclear factor 3-alpha homolog B) (HNF3alpha homolog B) (xHNF3alpha-B).
Probable transcription factor.
 foxa1-b ELISA Kit
 foxa1-b Recombinant
 foxa1-b Antibody
 fkh2 ELISA Kit
 fkh2 Recombinant
 fkh2 Antibody
Table BarTOPTable Bar
 

Forkhead box protein A2

 Forkhead box protein A2 ELISA Kit
 Forkhead box protein A2 Recombinant
 Forkhead box protein A2 Antibody
Also known as Forkhead box protein A2 (Axial protein).
May play a crucial role in specification of both the axial mesendoderm and the ventral nervous system.
 foxa2 ELISA Kit
 foxa2 Recombinant
 foxa2 Antibody
 axial ELISA Kit
 axial Recombinant
 axial Antibody
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Forkhead box protein A2-A

 Forkhead box protein A2-A ELISA Kit
 Forkhead box protein A2-A Recombinant
 Forkhead box protein A2-A Antibody
Also known as Forkhead box protein A2-A (FoxA2-A) (FoxA2a) (Fork head domain-related protein 3) (xFD-3) (Hepatocyte nuclear factor 3-beta homolog A) (HNF-3-beta-A) (HNF3-beta homolog A) (HNF3-beta-A) (xHNF3-beta-A) (xbeta-1).
Acts as a transcriptional activator during early development, limiting the extent of mesoderm formation in the gastrula. Binds to DNA via the target sequence 5'-GT[AC]AACA
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-3', with 5'-GTAAACA-3' being the preferred binding site.
 foxa2-a ELISA Kit
 foxa2-a Recombinant
 foxa2-a Antibody
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Forkhead box protein A2-B

 Forkhead box protein A2-B ELISA Kit
 Forkhead box protein A2-B Recombinant
 Forkhead box protein A2-B Antibody
Also known as Forkhead box protein A2-B (FoxA2-B) (FoxA2b) (Fork head domain-related protein 3') (xFD-3') (Hepatocyte nuclear factor 3-beta homolog B) (HNF-3-beta-B) (HNF3-beta homolog B) (HNF3-beta-B) (xHNF3-beta-B).
Acts as a transcriptional activator during early development, limiting the extent of mesoderm formation in the gastrula. Binds to DNA via the target sequence 5'-GT[AC]AACA-3', wit
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h 5'-GTAAACA-3' being the preferred binding site ().
 foxa2-b ELISA Kit
 foxa2-b Recombinant
 foxa2-b Antibody
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Forkhead box protein A4

 Forkhead box protein A4 ELISA Kit
 Forkhead box protein A4 Recombinant
 Forkhead box protein A4 Antibody
Also known as Forkhead box protein A4 (FoxA4).
Transcriptional repressor involved in embryonic nervous system development. Plays a role in the induction and patterning of the anterior-posterior neural axis. Involved in the establishment of floor plate differentiation from neural plate cells during gastrulation. Binds the anf1 promoter sequence to restrict expression of anf1 to the anterior of t
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he neural plate, thereby patterning the forebrain. Can bind to the HNF-3-alpha DNA target sequence. Cooperates with t/bra in a dose-dependent manner to specify dorsal mesoderm formation, including notochord. May be involved in the dorso-ventral patterning of the mesoderm. Binds to DNA via the target sequence 5'-[GA]TAAA[TC]A-3', with 5'-GTAAATA-3' being the preferred binding site ().
 foxa4 ELISA Kit
 foxa4 Recombinant
 foxa4 Antibody
 TGas072p11.1 ELISA Kit
 TGas072p11.1 Recombinant
 TGas072p11.1 Antibody
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Forkhead box protein A4-A

 Forkhead box protein A4-A ELISA Kit
 Forkhead box protein A4-A Recombinant
 Forkhead box protein A4-A Antibody
Also known as Forkhead box protein A4-A (FoxA4-A) (FoxA4a) (Fork head domain-related protein 1) (xFD-1) (Protein pintallavis).
Transcriptional repressor involved in embryonic nervous system development. Plays a role in the induction and patterning of the anterior-posterior neural axis. Involved in the establishment of floor plate differentiation from neural plate cells during gastrulation. Bind
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s the anf1 promoter sequence to restrict expression of anf1 to the anterior of the neural plate, thereby patterning the forebrain. Can bind to the HNF-3-alpha DNA target sequence. Cooperates with t/bra in a dose-dependent manner to specify dorsal mesoderm formation, including notochord. Binds to DNA via the target sequence 5'-[GA]TAAA[TC]A-3', with 5'-GTAAATA-3' being the preferred binding site.
 foxa4-a ELISA Kit
 foxa4-a Recombinant
 foxa4-a Antibody
Table BarTOPTable Bar
 

Forkhead box protein A4-B

 Forkhead box protein A4-B ELISA Kit
 Forkhead box protein A4-B Recombinant
 Forkhead box protein A4-B Antibody
Also known as Forkhead box protein A4-B (FoxA4-B) (FoxA4b) (Fork head domain-related protein 1') (FKH-1) (Forkhead protein 1) (xFD-1') (xFKH1).
Transcriptional repressor involved in embryonic nervous system development. Plays a role in the induction and patterning of the anterior-posterior neural axis. Involved in the establishment of floor plate differentiation from neural plate cells during g
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astrulation. Binds the anf1 promoter sequence to restrict expression of anf1 to the anterior of the neural plate, thereby patterning the forebrain. Can bind to the HNF-3-alpha DNA target sequence. Cooperates with t/bra in a dose-dependent manner to specify dorsal mesoderm formation, including notochord. May be involved in the dorso-ventral patterning of the mesoderm. Binds to DNA via the target sequence 5'-[GA]TAAA[TC]A-3', with 5'-GTAAATA-3' being the preferred binding site ().
 foxa4-b ELISA Kit
 foxa4-b Recombinant
 foxa4-b Antibody
 fkh1 ELISA Kit
 fkh1 Recombinant
 fkh1 Antibody
Table BarTOPTable Bar
 

Forkhead box protein B1

 Forkhead box protein B1 ELISA Kit
 Forkhead box protein B1 Recombinant
 Forkhead box protein B1 Antibody
Also known as Forkhead box protein B1 (FoxB1) (Transcription factor FKH-5).
Probable transcription factor. May be involved in the early anteroposterior patterning of the neuroectoderm.
 foxb1 ELISA Kit
 foxb1 Recombinant
 foxb1 Antibody
 fkh5 ELISA Kit
 fkh5 Recombinant
 fkh5 Antibody
Table BarTOPTable Bar
 

Forkhead box protein B2

 Forkhead box protein B2 ELISA Kit
 Forkhead box protein B2 Recombinant
 Forkhead box protein B2 Antibody
FOXB2: Transcription factor (Probable).

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 9q21.2

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding
 FOXB2 ELISA Kit
 FOXB2 Recombinant
 FOXB2 Antibody
Table BarTOPTable Bar
 

Forkhead box protein C1

 Forkhead box protein C1 ELISA Kit
 Forkhead box protein C1 Recombinant
 Forkhead box protein C1 Antibody
Transcription factor required at the gastrula stage for expression of several mesodermal and endodermal genes. At the late neurula stage, regulates expression of adhesion genes to maintain cell adhesion in the mesodermal germ layer ().
 foxc1 ELISA Kit
 foxc1 Recombinant
 foxc1 Antibody
Table BarTOPTable Bar
 

Forkhead box protein C1-A

 Forkhead box protein C1-A ELISA Kit
 Forkhead box protein C1-A Recombinant
 Forkhead box protein C1-A Antibody
Also known as Forkhead box protein C1-A (FoxC1) (Fork head domain-related protein 11) (XFD-11).
Transcription factor required at the gastrula stage for expression of several mesodermal and endodermal genes. At the late neurula stage, regulates expression of adhesion genes to maintain cell adhesion in the mesodermal germ layer.
 foxc1-a ELISA Kit
 foxc1-a Recombinant
 foxc1-a Antibody
 foxc1 ELISA Kit
 foxc1 Recombinant
 foxc1 Antibody
Table BarTOPTable Bar
 

Forkhead box protein C1-B

 Forkhead box protein C1-B ELISA Kit
 Forkhead box protein C1-B Recombinant
 Forkhead box protein C1-B Antibody
Transcription factor required at the gastrula stage for expression of several mesodermal and endodermal genes. At the late neurula stage, regulates expression of adhesion genes to maintain cell adhesion in the mesodermal germ layer ().
 foxc1-b ELISA Kit
 foxc1-b Recombinant
 foxc1-b Antibody
 foxc1 ELISA Kit
 foxc1 Recombinant
 foxc1 Antibody
Table BarTOPTable Bar
 

Forkhead box protein C2

 Forkhead box protein C2 ELISA Kit
 Forkhead box protein C2 Recombinant
 Forkhead box protein C2 Antibody
Also known as Forkhead box protein C2 (Brain factor 3) (BF-3) (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).
FOXC2: Transcriptional activator. Might be involved in the formation of special mesenchymal tissues. Defects in FOXC2 are the cause of lymphedema hereditary type 2 (LMPH2); also known as Meige lymphedema. Hereditary lymphedema is a chronic disabling condition which results in swelling of the extremities due to altered lymphatic flow. Patients with lymphedema suffer from recurrent local infections, and physical impairm
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ent. Defects in FOXC2 are a cause of lymphedema-yellow nails (LYYN). LYYN is characterized by yellow, dystrophic, thick and slowly growing nails, associated with lymphedema and respiratory involvement. Lymphedema occurs more often in the lower limbs. It can appear at birth or later in life. Onset generally follows the onset of ungual abnormalities. Defects in FOXC2 are a cause of lymphedema-distichiasis (LYD). LYD is characterized by primary limb lymphedema usually starting at puberty (but in some cases later or at birth) and associated with distichiasis (double rows of eyelashes, with extra eyelashes growing from the Meibomian gland orifices).

Protein type: Apoptosis; Cell development/differentiation; DNA-binding; Transcription factor

Cellular Component: nucleus

Molecular Function: chromatin DNA binding; DNA binding; RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding; transcription factor activity

Biological Process: artery morphogenesis; blood vessel development; blood vessel remodeling; camera-type eye development; cardiac muscle cell proliferation; cell proliferation; collagen fibril organization; embryonic cranial skeleton morphogenesis; embryonic heart tube development; embryonic skeletal morphogenesis; embryonic viscerocranium morphogenesis; heart development; heart morphogenesis; insulin receptor signaling pathway; kidney development; lymph vessel development; lymphangiogenesis; metanephros development; negative regulation of transcription from RNA polymerase II promoter; neural crest cell development; Notch signaling pathway; ossification; paraxial mesoderm formation; paraxial mesodermal cell fate commitment; patterning of blood vessels; positive regulation of cell adhesion mediated by integrin; positive regulation of integrin activation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of blood vessel size; regulation of organ growth; response to hormone stimulus; skeletal development; somitogenesis; ureteric bud development; vascular endothelial growth factor receptor signaling pathway; ventricular cardiac muscle morphogenesis
 Foxc2 ELISA Kit
 Foxc2 Recombinant
 Foxc2 Antibody
 Fkh14 ELISA Kit
 Fkh14 Recombinant
 Fkh14 Antibody
 Fkhl14 ELISA Kit
 Fkhl14 Recombinant
 Fkhl14 Antibody
 Mfh1 ELISA Kit
 Mfh1 Recombinant
 Mfh1 Antibody
Table BarTOPTable Bar
 

Forkhead box protein C2-A

 Forkhead box protein C2-A ELISA Kit
 Forkhead box protein C2-A Recombinant
 Forkhead box protein C2-A Antibody
Also known as Forkhead box protein C2-A (FoxC2-A) (FoxC2a) (Fork head domain-related protein 4) (FD-4) (xFD-4) (xFD4 A) (Forkhead protein 7) (FKH-7) (xFKH7).
Transcriptional activator (). May be involved in the dorso-ventral patterning of the mesoderm.
 foxc2-a ELISA Kit
 foxc2-a Recombinant
 foxc2-a Antibody
 fkh7 ELISA Kit
 fkh7 Recombinant
 fkh7 Antibody
Table BarTOPTable Bar
 

Forkhead box protein C2-B

 Forkhead box protein C2-B ELISA Kit
 Forkhead box protein C2-B Recombinant
 Forkhead box protein C2-B Antibody
Also known as Forkhead box protein C2-B (FoxC2-B) (FoxC2b) (Fork head domain-related protein 4') (FD-4') (xFD-4') (xFD4 B).
Transcriptional activator. May be involved in the dorso-ventral patterning of the mesoderm ().
 foxc2-b ELISA Kit
 foxc2-b Recombinant
 foxc2-b Antibody
Table BarTOPTable Bar
 

Forkhead box protein D1

 Forkhead box protein D1 ELISA Kit
 Forkhead box protein D1 Recombinant
 Forkhead box protein D1 Antibody
Also known as Forkhead box protein D1 (Brain factor 2) (BF-2) (cBF-2) (HFH-BF-2) (T-14-6).
May determine the nasotemporal axis of the retina, and consequently specify the topographical projection of the retinal ganglion-cell axons to the tectum by controlling expression of their target genes.
 FOXD1 ELISA Kit
 FOXD1 Recombinant
 FOXD1 Antibody
 HFHBF2 ELISA Kit
 HFHBF2 Recombinant
 HFHBF2 Antibody
Table BarTOPTable Bar
 

Forkhead box protein D2

 Forkhead box protein D2 ELISA Kit
 Forkhead box protein D2 Recombinant
 Forkhead box protein D2 Antibody
Also known as Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead-related transcription factor 9) (FREAC-9).
FOXD2: Probable transcription factor involved in embryogenesis and somatogenesis.

Protein type: Cell development/differentiation; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 1p34-p32

Cellular Component: nucleus

Molecular Function: transcription factor activity
 FOXD2 ELISA Kit
 FOXD2 Recombinant
 FOXD2 Antibody
 FKHL17 ELISA Kit
 FKHL17 Recombinant
 FKHL17 Antibody
 FREAC9 ELISA Kit
 FREAC9 Recombinant
 FREAC9 Antibody
Table BarTOPTable Bar
 

Forkhead box protein D3

 Forkhead box protein D3 ELISA Kit
 Forkhead box protein D3 Recombinant
 Forkhead box protein D3 Antibody
Also known as Forkhead box protein D3 (FoxD3).
Transcriptional repressor that is an essential upstream regulator of neural crest determination. Also acts in a negative auto-regulator loop by inhibiting the transcription of its own gene ().
 foxd3 ELISA Kit
 foxd3 Recombinant
 foxd3 Antibody
 TNeu088c09.1 ELISA Kit
 TNeu088c09.1 Recombinant
 TNeu088c09.1 Antibody
Table BarTOPTable Bar
 

Forkhead box protein D3-A

 Forkhead box protein D3-A ELISA Kit
 Forkhead box protein D3-A Recombinant
 Forkhead box protein D3-A Antibody
Also known as Forkhead box protein D3-A (FoxD3-A) (FoxD3a) (Fork head domain-related protein 6) (FKH-6) (Forkhead protein 6) (xFD-6) (xFKH6).
Transcriptional repressor that is an essential upstream regulator of neural crest determination and mesoderm induction. Functions by recruiting the transcriptional corepressor tle4. Also acts in a negative auto-regulator loop by inhibiting the transcription of its own gene.
 foxd3-a ELISA Kit
 foxd3-a Recombinant
 foxd3-a Antibody
 fkh6 ELISA Kit
 fkh6 Recombinant
 fkh6 Antibody
 foxd3a ELISA Kit
 foxd3a Recombinant
 foxd3a Antibody
Table BarTOPTable Bar
 

Forkhead box protein D3-B

 Forkhead box protein D3-B ELISA Kit
 Forkhead box protein D3-B Recombinant
 Forkhead box protein D3-B Antibody
Also known as Forkhead box protein D3-B (FoxD3-B) (FoxD3b) (Fork head domain-related protein 6') (xFD-6').
Transcriptional repressor that is an essential upstream regulator of neural crest determination and mesoderm induction. Functions by recruiting the transcriptional corepressor tle4. Also acts in a negative auto-regulator loop by inhibiting the transcription of its own gene.
 foxd3-b ELISA Kit
 foxd3-b Recombinant
 foxd3-b Antibody
 foxd3b ELISA Kit
 foxd3b Recombinant
 foxd3b Antibody
Table BarTOPTable Bar
 

Forkhead box protein D4

 Forkhead box protein D4 ELISA Kit
 Forkhead box protein D4 Recombinant
 Forkhead box protein D4 Antibody
Also known as Forkhead box protein D4 (Forkhead-related protein FKHL9) (Forkhead-related transcription factor 5) (FREAC-5) (Hepatocyte nuclear factor 3 forkhead homolog 6) (HFH-6).
FOXD4L1:

Protein type: DNA-binding

Cellular Component: nucleus
 Foxd4 ELISA Kit
 Foxd4 Recombinant
 Foxd4 Antibody
 Fkhl9 ELISA Kit
 Fkhl9 Recombinant
 Fkhl9 Antibody
 Freac5 ELISA Kit
 Freac5 Recombinant
 Freac5 Antibody
 Hfh6 ELISA Kit
 Hfh6 Recombinant
 Hfh6 Antibody
Table BarTOPTable Bar
 

Forkhead box protein D4-like 1

 Forkhead box protein D4-like 1 ELISA Kit
 Forkhead box protein D4-like 1 Recombinant
 Forkhead box protein D4-like 1 Antibody
Also known as Forkhead box protein D4-like 1 (FOXD4-like 1).
FOXD4L1:

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 2q13

Cellular Component: nucleus
 FOXD4L1 ELISA Kit
 FOXD4L1 Recombinant
 FOXD4L1 Antibody
Table BarTOPTable Bar
 

Forkhead box protein D4-like 3

 Forkhead box protein D4-like 3 ELISA Kit
 Forkhead box protein D4-like 3 Recombinant
 Forkhead box protein D4-like 3 Antibody
Also known as Forkhead box protein D4-like 3 (FOXD4-like 3).
FOXD4L3:

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 9q21.11

Cellular Component: nucleus
 FOXD4L3 ELISA Kit
 FOXD4L3 Recombinant
 FOXD4L3 Antibody
Table BarTOPTable Bar
 

Forkhead box protein D4-like 4

 Forkhead box protein D4-like 4 ELISA Kit
 Forkhead box protein D4-like 4 Recombinant
 Forkhead box protein D4-like 4 Antibody
Also known as Forkhead box protein D4-like 4 (FOXD4-like 4) (Forkhead box protein D4-like 2) (Forkhead box protein D4B) (Myeloid factor-gamma).
FOXD4L4:

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 9q21.11

Cellular Component: nucleus
 FOXD4L4 ELISA Kit
 FOXD4L4 Recombinant
 FOXD4L4 Antibody
 FOXD4B ELISA Kit
 FOXD4B Recombinant
 FOXD4B Antibody
 FOXD4L2 ELISA Kit
 FOXD4L2 Recombinant
 FOXD4L2 Antibody
Table BarTOPTable Bar
 

Forkhead box protein D4-like 5

 Forkhead box protein D4-like 5 ELISA Kit
 Forkhead box protein D4-like 5 Recombinant
 Forkhead box protein D4-like 5 Antibody
Also known as Forkhead box protein D4-like 5 (FOXD4-like 5).
FOXD4L5:

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 9q21.11

Cellular Component: nucleus
 FOXD4L5 ELISA Kit
 FOXD4L5 Recombinant
 FOXD4L5 Antibody
Table BarTOPTable Bar
 

Forkhead box protein D4-like 6

 Forkhead box protein D4-like 6 ELISA Kit
 Forkhead box protein D4-like 6 Recombinant
 Forkhead box protein D4-like 6 Antibody
Also known as Forkhead box protein D4-like 6 (FOXD4-like 6).
FOXD4L6:

Protein type: Cell development/differentiation; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 9q21.11

Cellular Component: nucleus

Molecular Function: protein binding
 FOXD4L6 ELISA Kit
 FOXD4L6 Recombinant
 FOXD4L6 Antibody
Table BarTOPTable Bar
 

Forkhead box protein D5

 Forkhead box protein D5 ELISA Kit
 Forkhead box protein D5 Recombinant
 Forkhead box protein D5 Antibody
Also known as Forkhead box protein D5 (FoxD5) (XtFoxD5).
Transcriptional repressor.
 foxd5 ELISA Kit
 foxd5 Recombinant
 foxd5 Antibody
 TGas140e03.1 ELISA Kit
 TGas140e03.1 Recombinant
 TGas140e03.1 Antibody
Table BarTOPTable Bar
 

Forkhead box protein D5-A

 Forkhead box protein D5-A ELISA Kit
 Forkhead box protein D5-A Recombinant
 Forkhead box protein D5-A Antibody
Also known as Forkhead box protein D5-A (FoxD5-A) (FoxD5a) (Fork head domain-related protein 12) (xFD-12) (XlFoxD5a).
Transcriptional repressor with a role in dorsal axis formation and neural plate expansion; maintains an undifferentiated neural ectoderm after neural induction.
 foxd5-a ELISA Kit
 foxd5-a Recombinant
 foxd5-a Antibody
 foxd5a ELISA Kit
 foxd5a Recombinant
 foxd5a Antibody
Table BarTOPTable Bar
 

Forkhead box protein D5-B

 Forkhead box protein D5-B ELISA Kit
 Forkhead box protein D5-B Recombinant
 Forkhead box protein D5-B Antibody
Also known as Forkhead box protein D5-B (FoxD5-B) (FoxD5b) (Fork head domain protein 3) (Fork head domain-related protein 12') (xFD-12') (Forkhead-like) (xFLIP) (XlFoxD5b).
Transcriptional repressor (). Controls the convergence and extension movements of medial neural plate precursors during gastrulation.
 foxd5-b ELISA Kit
 foxd5-b Recombinant
 foxd5-b Antibody
 fhd3 ELISA Kit
 fhd3 Recombinant
 fhd3 Antibody
 fkh-l ELISA Kit
 fkh-l Recombinant
 fkh-l Antibody
 foxd5b ELISA Kit
 foxd5b Recombinant
 foxd5b Antibody
Table BarTOPTable Bar
 

Forkhead box protein D5-C

 Forkhead box protein D5-C ELISA Kit
 Forkhead box protein D5-C Recombinant
 Forkhead box protein D5-C Antibody
Also known as Forkhead box protein D5-C (FoxD5-C) (FoxD5c) (Fork head domain-related protein 12'') (xFD-12'') (XlFoxD5c).
Transcriptional repressor.
 foxd5-c ELISA Kit
 foxd5-c Recombinant
 foxd5-c Antibody
 foxd5c ELISA Kit
 foxd5c Recombinant
 foxd5c Antibody
Table BarTOPTable Bar
 

Forkhead box protein E1

 Forkhead box protein E1 ELISA Kit
 Forkhead box protein E1 Recombinant
 Forkhead box protein E1 Antibody
Also known as Forkhead box protein E1 (Forkhead box protein E2) (Forkhead-related protein FKHL15) (HFKH4) (HNF-3/fork head-like protein 5) (HFKL5) (Thyroid transcription factor 2) (TTF-2).
FOXE1: Probable transcription factor. Could be involved in thyroid gland organogenesis. Defects in FOXE1 are the cause of Bamforth-Lazarus syndrome (BLS). BLS is associated with thyroid agenesis, cleft palate and choanal atresia.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 9q22

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding;
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transcription factor activity

Biological Process: cell migration; embryonic organ morphogenesis; hair follicle morphogenesis; hard palate development; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; soft palate development; thymus development; thyroid gland development; thyroid hormone generation

Disease: Hypothyroidism, Athyroidal, With Spiky Hair And Cleft Palate; Thyroid Cancer, Nonmedullary, 4
 FOXE1 ELISA Kit
 FOXE1 Recombinant
 FOXE1 Antibody
 FKHL15 ELISA Kit
 FKHL15 Recombinant
 FKHL15 Antibody
 FOXE2 ELISA Kit
 FOXE2 Recombinant
 FOXE2 Antibody
 TITF2 ELISA Kit
 TITF2 Recombinant
 TITF2 Antibody
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Forkhead box protein E3

 Forkhead box protein E3 ELISA Kit
 Forkhead box protein E3 Recombinant
 Forkhead box protein E3 Antibody
FOXE3: Defects in FOXE3 are a cause of anterior segment mesenchymal dysgenesis (ASMD); also known as anterior segment ocular dysgenesis (ASOD). ASMD consists of a range of developmental defects in structures at the front of the eye, resulting from abnormal migration or differentiation of the neural crest derived mesenchymal cells that give rise to the cornea, iris, and other components of the ante
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rior chamber during eye development. Mature anterior segment anomalies are associated with an increased risk of glaucoma and corneal opacity. Conditions falling within the phenotypic spectrum include aniridia, posterior embryotoxon, Axenfeld anomaly, Reiger anomaly/syndrome, Peters anomaly, and iridogoniodysgenesis. Defects in FOXE3 are a cause of congenital primary aphakia (CPA). Aphakia is a rare congenital eye disorder in which the lens is missing. It has been histologically subdivided into primary and secondary forms, in accordance with the severity of defects of the ocular tissues, whose development requires the initial presence of a lens. CPA results from an early developmental arrest, around the 4th-5th week of gestation in humans, that prevents the formation of any lens structure and leads to severe secondary ocular defects, including a complete aplasia of the anterior segment of the eye. In contrast, in secondary aphakic eyes, lens induction has occurred, and the lens vesicle has developed to some degree but finally has progressively resorbed perinatally, leading, therefore, to less-severe ocular defects.

Protein type: DNA-binding

Cellular Component: nucleus; transcription factor complex

Molecular Function: sequence-specific DNA binding; transcription factor activity

Biological Process: camera-type eye development; cell development; eye development; lens development in camera-type eye; negative regulation of apoptosis; positive regulation of epithelial cell proliferation; transcription from RNA polymerase II promoter
 Foxe3 ELISA Kit
 Foxe3 Recombinant
 Foxe3 Antibody
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Forkhead box protein E4

 Forkhead box protein E4 ELISA Kit
 Forkhead box protein E4 Recombinant
 Forkhead box protein E4 Antibody
Also known as Forkhead box protein E4 (FoxE4) (Xlens1).
Probable transcription factor. Mediates lens formation in the embryo by promoting the proliferation of the specified lens ectoderm and suppressing its terminal differentiation.
 foxe4 ELISA Kit
 foxe4 Recombinant
 foxe4 Antibody
 lens1 ELISA Kit
 lens1 Recombinant
 lens1 Antibody
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Forkhead box protein F1

 Forkhead box protein F1 ELISA Kit
 Forkhead box protein F1 Recombinant
 Forkhead box protein F1 Antibody
 foxf1 ELISA Kit
 foxf1 Recombinant
 foxf1 Antibody
 si:dkey-199i24.2 ELISA Kit
 si:dkey-199i24.2 Recombinant
 si:dkey-199i24.2 Antibody
 zgc:158301 ELISA Kit
 zgc:158301 Recombinant
 zgc:158301 Antibody
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Forkhead box protein F1-A

 Forkhead box protein F1-A ELISA Kit
 Forkhead box protein F1-A Recombinant
 Forkhead box protein F1-A Antibody
Also known as Forkhead box protein F1-A (FoxF1-A) (FoxF1a) (Fork head domain-related protein 13) (xFD-13).
Probable transcription factor. Required for smooth muscle (visceral mesoderm) differentiation during gut development. Also required for normal proliferation of the lateral plate mesoderm. Acts as a downstream mediator of bmp4-signaling ().
 foxf1-a ELISA Kit
 foxf1-a Recombinant
 foxf1-a Antibody
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Forkhead box protein F1-B

 Forkhead box protein F1-B ELISA Kit
 Forkhead box protein F1-B Recombinant
 Forkhead box protein F1-B Antibody
Also known as Forkhead box protein F1-B (FoxF1-B) (FoxF1b) (Fork head domain-related protein 13') (xFD-13').
Probable transcription factor. Required for smooth muscle (visceral mesoderm) differentiation during gut development. Also required for normal proliferation of the lateral plate mesoderm. Acts as a downstream mediator of bmp4-signaling.
 foxf1-b ELISA Kit
 foxf1-b Recombinant
 foxf1-b Antibody
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Forkhead box protein F2

 Forkhead box protein F2 ELISA Kit
 Forkhead box protein F2 Recombinant
 Forkhead box protein F2 Antibody
Also known as Forkhead box protein F2 (Forkhead-related activator 2) (FREAC-2) (Forkhead-related protein FKHL6) (Forkhead-related transcription factor 2).
FOXF2: Probable transcription activator for a number of lung- specific genes.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 6p25.3

Cellular Component: nucleus; transcription factor complex

Molecular Function: DNA binding; RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding; transcription factor activity; transcription factor binding

Biologi
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cal Process: genitalia development; palate development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent
 FOXF2 ELISA Kit
 FOXF2 Recombinant
 FOXF2 Antibody
 FKHL6 ELISA Kit
 FKHL6 Recombinant
 FKHL6 Antibody
 FREAC2 ELISA Kit
 FREAC2 Recombinant
 FREAC2 Antibody
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Forkhead box protein G1

 Forkhead box protein G1 ELISA Kit
 Forkhead box protein G1 Recombinant
 Forkhead box protein G1 Antibody
Also known as Forkhead box protein G1 (Brain factor 1) (BF-1) (BF1) (Brain factor 2) (BF-2) (BF2) (hBF-2) (Forkhead box protein G1A) (Forkhead box protein G1B) (Forkhead box protein G1C) (Forkhead-related protein FKHL1) (HFK1) (Forkhead-related protein FKHL2) (HFK2) (Forkhead-related protein FKHL3) (HFK3).
FOXG1: Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon. Interacts with KDM5B. Expression is restricted to the neurons of the developing telencephalon.

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Protein type: DNA-binding; Nuclear receptor co-regulator; Transcription factor

Chromosomal Location of Human Ortholog: 14q13

Cellular Component: nucleus

Molecular Function: DNA binding; protein binding

Biological Process: brain development; negative regulation of transcription, DNA-dependent

Disease: Rett Syndrome, Congenital Variant
 FOXG1 ELISA Kit
 FOXG1 Recombinant
 FOXG1 Antibody
 FKH2 ELISA Kit
 FKH2 Recombinant
 FKH2 Antibody
 FKHL1 ELISA Kit
 FKHL1 Recombinant
 FKHL1 Antibody
 FKHL2 ELISA Kit
 FKHL2 Recombinant
 FKHL2 Antibody
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Forkhead box protein H1

 Forkhead box protein H1 ELISA Kit
 Forkhead box protein H1 Recombinant
 Forkhead box protein H1 Antibody
Also known as Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast-1).
Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Upon TGF-beta induction, forms a transcriptionally active complex with smad2 and smad4 called activin-responsive factor 1 (ARF1), which binds a site on the mix-B/mix.2 promoter called the activin response element (ARE).
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Binds to activated smads and the ARE with much lower affinity than fast3. Necessary for the first steps in mesoderm specification, directly inducing mesodermal genes. Acts with fast3 to control the convergent extension movements of gastrulation. Binds to the proximal element (PE) of the gsc gene and cooperates with gtf2ird1/wbscr11 and SMAD proteins to regulate gsc transcription ().
 foxh1 ELISA Kit
 foxh1 Recombinant
 foxh1 Antibody
 TGas103n06.1 ELISA Kit
 TGas103n06.1 Recombinant
 TGas103n06.1 Antibody
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Forkhead box protein I1

 Forkhead box protein I1 ELISA Kit
 Forkhead box protein I1 Recombinant
 Forkhead box protein I1 Antibody
FOXI1: Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epi
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thelium of distal renal tubules. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding; transcription factor activity

Biological Process: inner ear morphogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent
 Foxi1 ELISA Kit
 Foxi1 Recombinant
 Foxi1 Antibody
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Forkhead box protein I1-A

 Forkhead box protein I1-A ELISA Kit
 Forkhead box protein I1-A Recombinant
 Forkhead box protein I1-A Antibody
Also known as Forkhead box protein I1-A (FoxI1-A) (FoxI1a) (xFoxI1a) (Fork head domain-related protein 2) (xFD-2) (xFD2).
Transcription factor. Essential for ventral specification of the early cephalic (head) ectoderm during gastrulation, playing a role in the non-neural versus neural cell fate choice. Binds to DNA via the target sequence 5'-[AG]TAAA[CT]A-3', with 5'-ATAAACA-3' being the prefer
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red binding site.
 foxi1-a ELISA Kit
 foxi1-a Recombinant
 foxi1-a Antibody
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Forkhead box protein I1-B

 Forkhead box protein I1-B ELISA Kit
 Forkhead box protein I1-B Recombinant
 Forkhead box protein I1-B Antibody
Also known as Forkhead box protein I1-B (FoxI1-B) (FoxI1b) (xFoxI1b) (Fork head domain-related protein 2') (xFD-2') (xFD2').
Transcription factor. Essential for ventral specification of the early cephalic (head) ectoderm during gastrulation, playing a role in the 'non-neural' versus 'neural' cell fate choice. Binds to DNA via the target sequence 5'-[AG]TAAA[CT]A-3', with 5'-ATAAACA-3' being the
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preferred binding site.
 foxi1-b ELISA Kit
 foxi1-b Recombinant
 foxi1-b Antibody
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Forkhead box protein I1c

 Forkhead box protein I1c ELISA Kit
 Forkhead box protein I1c Recombinant
 Forkhead box protein I1c Antibody
Also known as Forkhead box protein I1c (FoxI1c).
Probable transcription factor.
 foxi1c ELISA Kit
 foxi1c Recombinant
 foxi1c Antibody
 TGas113f01.1 ELISA Kit
 TGas113f01.1 Recombinant
 TGas113f01.1 Antibody
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Forkhead box protein I1-ema

 Forkhead box protein I1-ema ELISA Kit
 Forkhead box protein I1-ema Recombinant
 Forkhead box protein I1-ema Antibody
Also known as Forkhead box protein I1-ema (FoxI1-ema) (Ectodermally-expressed mesendoderm antagonist) (FoxI3).
Transcriptional activator. Activates ectoderm, in addition to inhibiting mesoderm and endoderm formation; required at the blastula stage for normal formation of both the central nervous system and epidermis, the two early derivatives of the ectoderm. In addition, also required to maintain the regional identity of the animal cells of the blastula, the cells that are precursors of ectodermal structures. Also plays a role in differential adhesion, which limits cell mixing as primary g
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erm layers become specified ().
 foxi1e ELISA Kit
 foxi1e Recombinant
 foxi1e Antibody
 ema ELISA Kit
 ema Recombinant
 ema Antibody
 foxi1 ELISA Kit
 foxi1 Recombinant
 foxi1 Antibody
 foxi3 ELISA Kit
 foxi3 Recombinant
 foxi3 Antibody
Table BarTOPTable Bar
 

Forkhead box protein I2

 Forkhead box protein I2 ELISA Kit
 Forkhead box protein I2 Recombinant
 Forkhead box protein I2 Antibody
FOXI2: Possible transcriptional activator.

Protein type: Cell development/differentiation; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 10q26.2

Cellular Component: nucleus
 FOXI2 ELISA Kit
 FOXI2 Recombinant
 FOXI2 Antibody
Table BarTOPTable Bar
 

Forkhead box protein I2-A

 Forkhead box protein I2-A ELISA Kit
 Forkhead box protein I2-A Recombinant
 Forkhead box protein I2-A Antibody
Also known as Forkhead box protein I2-A (XlFoxI2-A).
Possible transcriptional activator.
 foxi2-a ELISA Kit
 foxi2-a Recombinant
 foxi2-a Antibody
Table BarTOPTable Bar
 

Forkhead box protein I2-B

 Forkhead box protein I2-B ELISA Kit
 Forkhead box protein I2-B Recombinant
 Forkhead box protein I2-B Antibody
Also known as Forkhead box protein I2-B (XlFoxI2-B).
Possible transcriptional activator.
 foxi2-b ELISA Kit
 foxi2-b Recombinant
 foxi2-b Antibody
Table BarTOPTable Bar
 

Forkhead box protein I3

 Forkhead box protein I3 ELISA Kit
 Forkhead box protein I3 Recombinant
 Forkhead box protein I3 Antibody
Possible transcriptional factor. May play a role in the development of the epithelium of hair and whisker placodes and that of teeth.
 FOXI3 ELISA Kit
 FOXI3 Recombinant
 FOXI3 Antibody
Table BarTOPTable Bar
 

Forkhead box protein J1

 Forkhead box protein J1 ELISA Kit
 Forkhead box protein J1 Recombinant
 Forkhead box protein J1 Antibody
Also known as Forkhead box protein J1 (Forkhead-related protein FKHL13) (Hepatocyte nuclear factor 3 forkhead homolog 4) (HFH-4).
FOXJ1: May play an important role in cell fate determination during lung development and in spermatogenesis. Genetic variations in FOXJ1 may be associated with susceptibility to allergic rhinitis (ALRH). Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.

Protein type: DNA-binding; Transcription factor

Cellular Component: nucleus

Biological Process: actin cytos
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keleton organization and biogenesis; brain development; central tolerance induction; determination of left/right symmetry; establishment of apical/basal cell polarity; heart development; humoral immune response; inhibition of NF-kappaB transcription factor; leukocyte migration; negative regulation of B cell activation; negative regulation of germinal center formation; negative regulation of humoral immune response mediated by circulating immunoglobulin; negative regulation of interleukin-6 biosynthetic process; negative regulation of T cell differentiation in the thymus; negative regulation of T cell proliferation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of central B cell tolerance induction; positive regulation of transcription from RNA polymerase II promoter; regulation of epithelial cell differentiation
 Foxj1 ELISA Kit
 Foxj1 Recombinant
 Foxj1 Antibody
 Fkhl13 ELISA Kit
 Fkhl13 Recombinant
 Fkhl13 Antibody
 Hfh4 ELISA Kit
 Hfh4 Recombinant
 Hfh4 Antibody
Table BarTOPTable Bar
 

Forkhead box protein J1.2

 Forkhead box protein J1.2 ELISA Kit
 Forkhead box protein J1.2 Recombinant
 Forkhead box protein J1.2 Antibody
Also known as Forkhead box protein J1.2 (FoxJ1.2).
Key transcription factor required for motile ciliogenesis. Activates genes essential for motile cilia formation and function.
 foxj1.2 ELISA Kit
 foxj1.2 Recombinant
 foxj1.2 Antibody
Table BarTOPTable Bar
 

Forkhead box protein J1-A

 Forkhead box protein J1-A ELISA Kit
 Forkhead box protein J1-A Recombinant
 Forkhead box protein J1-A Antibody
Key transcription factor required for motile ciliogenesis. Activates genes essential for motile cilia formation and function. Its activity is sufficient for ectopic development of cilia that resemble motile cilia.
 foxj1a ELISA Kit
 foxj1a Recombinant
 foxj1a Antibody
 foxj1 ELISA Kit
 foxj1 Recombinant
 foxj1 Antibody
Table BarTOPTable Bar
 

Forkhead box protein J1-B

 Forkhead box protein J1-B ELISA Kit
 Forkhead box protein J1-B Recombinant
 Forkhead box protein J1-B Antibody
Key transcription factor required for motile ciliogenesis. Activates genes essential for motile cilia formation and function.
 foxj1b ELISA Kit
 foxj1b Recombinant
 foxj1b Antibody
 foxj1.2 ELISA Kit
 foxj1.2 Recombinant
 foxj1.2 Antibody
Table BarTOPTable Bar
 

Forkhead box protein J2

 Forkhead box protein J2 ELISA Kit
 Forkhead box protein J2 Recombinant
 Forkhead box protein J2 Antibody
Also known as Forkhead box protein J2 (Fork head homologous X).
FOXJ2: Transcriptional activator. Able to bind to two different type of DNA binding sites. Isoform FOXJ2.L behaves as a more potent transactivator than FOXJ2.S. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Cellular Component: nucleolus; nucleus >>>
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Biological Process: positive regulation of transcription from RNA polymerase II promoter
 Foxj2 ELISA Kit
 Foxj2 Recombinant
 Foxj2 Antibody
 Fhx ELISA Kit
 Fhx Recombinant
 Fhx Antibody
Table BarTOPTable Bar
 

Forkhead box protein J3

 Forkhead box protein J3 ELISA Kit
 Forkhead box protein J3 Recombinant
 Forkhead box protein J3 Antibody
FOXJ3: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Cellular Component: nucleus
 Foxj3 ELISA Kit
 Foxj3 Recombinant
 Foxj3 Antibody
 Kiaa1041 ELISA Kit
 Kiaa1041 Recombinant
 Kiaa1041 Antibody
Table BarTOPTable Bar
 

Forkhead box protein K1

 Forkhead box protein K1 ELISA Kit
 Forkhead box protein K1 Recombinant
 Forkhead box protein K1 Antibody
Also known as Forkhead box protein K1 (Myocyte nuclear factor) (MNF).
FOXK1: Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli. 2 isoforms of the human protein are produced by alternative splicing.

Protein typ
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e: DNA-binding; Transcription factor

Cellular Component: nucleus

Molecular Function: DNA binding; protein binding; sequence-specific DNA binding

Biological Process: negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter
 Foxk1 ELISA Kit
 Foxk1 Recombinant
 Foxk1 Antibody
 Mnf ELISA Kit
 Mnf Recombinant
 Mnf Antibody
Table BarTOPTable Bar
 

Forkhead box protein K2

 Forkhead box protein K2 ELISA Kit
 Forkhead box protein K2 Recombinant
 Forkhead box protein K2 Antibody
Also known as Forkhead box protein K2 (Cellular transcription factor ILF-1) (FOXK1) (Interleukin enhancer-binding factor 1).
The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. [provided by RefSeq, Jul 2008]
 FOXK2 ELISA Kit
 FOXK2 Recombinant
 FOXK2 Antibody
 ILF ELISA Kit
 ILF Recombinant
 ILF Antibody
 ILF1 ELISA Kit
 ILF1 Recombinant
 ILF1 Antibody
Table BarTOPTable Bar
 

Forkhead box protein L1

 Forkhead box protein L1 ELISA Kit
 Forkhead box protein L1 Recombinant
 Forkhead box protein L1 Antibody
Also known as Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead-related transcription factor 7) (FREAC-7).
FOXL1: Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 16q24

Cellular Component: nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; transcription factor activity

Biological Process: heart develop
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ment; organ morphogenesis; proteoglycan biosynthetic process; regulation of Wnt receptor signaling pathway; visceral mesoderm-endoderm interaction involved in midgut development
 FOXL1 ELISA Kit
 FOXL1 Recombinant
 FOXL1 Antibody
 FKHL11 ELISA Kit
 FKHL11 Recombinant
 FKHL11 Antibody
 FREAC7 ELISA Kit
 FREAC7 Recombinant
 FREAC7 Antibody
Table BarTOPTable Bar
 

Forkhead box protein L2

 Forkhead box protein L2 ELISA Kit
 Forkhead box protein L2 Recombinant
 Forkhead box protein L2 Antibody
Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination (). Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (). Has apoptotic activity in ovarian cells (). Suppresses ESR1-mediated transcription of PTGS2/COX2 sti
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mulated by tamoxifen (). Activates SIRT1 transcription under cellular stress conditions (). Activates transcription of OSR2 (). Is a regulator of CYP19 expression (). Is a transcriptional repressor of STAR (). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element ().
 FOXL2 ELISA Kit
 FOXL2 Recombinant
 FOXL2 Antibody
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Forkhead box protein M1

 Forkhead box protein M1 ELISA Kit
 Forkhead box protein M1 Recombinant
 Forkhead box protein M1 Antibody
Also known as Forkhead box protein M1 (Forkhead homolog 16) (Winged-helix transcription factor Trident).
FOXM1: a transcriptional activator factor. Contains 1 fork-head domain. May play a role in the control of cell proliferation. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived
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from tumors. Not expressed in resting cells. Phosphorylated in M (mitotic) phase. Three splice variant isoforms have been described. Isoform 1 and isoform 2 appear to be the only activators of gene transcription. Isoform 3, found in rat, does not seem to exist in human.

Protein type: DNA-binding; Transcription factor

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: DNA binding; protein binding; protein kinase binding; sequence-specific DNA binding; transcription factor activity

Biological Process: DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; G2/M transition of mitotic cell cycle; liver development; negative regulation of stress-activated MAPK cascade; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of cell proliferation; regulation of Ras protein signal transduction; vasculogenesis
 Foxm1 ELISA Kit
 Foxm1 Recombinant
 Foxm1 Antibody
 Fkh16 ELISA Kit
 Fkh16 Recombinant
 Fkh16 Antibody
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Forkhead box protein N1

 Forkhead box protein N1 ELISA Kit
 Forkhead box protein N1 Recombinant
 Forkhead box protein N1 Antibody
Also known as Forkhead box protein N1 (Hepatocyte nuclear factor 3 forkhead homolog 11) (HFH-11) (HNF-3/forkhead homolog 11) (Winged-helix transcription factor nude).
FOXN1: Transcriptional regulator involved in development. Defects in FOXN1 are the cause of T-cell immunodeficiency congenital alopecia and nail dystrophy (TIDAND). A disorder characterized by the association of congenital alopecia, severe T-cell immunodeficiency, and ridging and pitting of all nails.

Protein type: Cell development/differentiation; DNA-binding; Transcription factor

Cellular Component: nucleus
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Biological Process: blood vessel morphogenesis; cell proliferation; epidermis development; epithelial cell proliferation; hair follicle development; hemopoiesis; keratinocyte differentiation; lymphocyte homeostasis; positive regulation of epithelial cell differentiation; positive regulation of hair follicle development; regulation of gene expression; regulation of T cell differentiation in the thymus; T cell homeostasis; T cell lineage commitment; thymus development
 Foxn1 ELISA Kit
 Foxn1 Recombinant
 Foxn1 Antibody
 Fkh19 ELISA Kit
 Fkh19 Recombinant
 Fkh19 Antibody
 Hfh11 ELISA Kit
 Hfh11 Recombinant
 Hfh11 Antibody
 Whn ELISA Kit
 Whn Recombinant
 Whn Antibody
Table BarTOPTable Bar
 

Forkhead box protein N2

 Forkhead box protein N2 ELISA Kit
 Forkhead box protein N2 Recombinant
 Forkhead box protein N2 Antibody
 foxn2 ELISA Kit
 foxn2 Recombinant
 foxn2 Antibody
 TGas051c08.1 ELISA Kit
 TGas051c08.1 Recombinant
 TGas051c08.1 Antibody
Table BarTOPTable Bar
 

Forkhead box protein N3

 Forkhead box protein N3 ELISA Kit
 Forkhead box protein N3 Recombinant
 Forkhead box protein N3 Antibody
Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints) ().
 foxn3 ELISA Kit
 foxn3 Recombinant
 foxn3 Antibody
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Forkhead box protein N4

 Forkhead box protein N4 ELISA Kit
 Forkhead box protein N4 Recombinant
 Forkhead box protein N4 Antibody
Transcription factor that may play a role in neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3' ().
 foxn4 ELISA Kit
 foxn4 Recombinant
 foxn4 Antibody
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Forkhead box protein N5

 Forkhead box protein N5 ELISA Kit
 Forkhead box protein N5 Recombinant
 Forkhead box protein N5 Antibody
 foxn5 ELISA Kit
 foxn5 Recombinant
 foxn5 Antibody
Table BarTOPTable Bar
 

Forkhead box protein O

 Forkhead box protein O ELISA Kit
 Forkhead box protein O Recombinant
 Forkhead box protein O Antibody
Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thord4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated
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and inhibits growth through the action of target genes such as Thor. Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself may function as one secondary messenger of insulin-regulated aging. Also regulates Lip4, homolog of human acid lipases, thereby acting as a key modulator of lipid metabolism by insulin signaling and integrates insulin responses to glucose and lipid homeostasis ().
 foxo ELISA Kit
 foxo Recombinant
 foxo Antibody
 GG16833 ELISA Kit
 GG16833 Recombinant
 GG16833 Antibody
Table BarTOPTable Bar
 

Forkhead box protein O1

 Forkhead box protein O1 ELISA Kit
 Forkhead box protein O1 Recombinant
 Forkhead box protein O1 Antibody
Also known as Forkhead box protein O1 (Forkhead box protein O1A) (Forkhead in rhabdomyosarcoma).
Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'
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-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death (). Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake (PubMed:18293098). Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner ().
 FOXO1 ELISA Kit
 FOXO1 Recombinant
 FOXO1 Antibody
 FOXO1A ELISA Kit
 FOXO1A Recombinant
 FOXO1A Antibody
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Forkhead box protein O1-A

 Forkhead box protein O1-A ELISA Kit
 Forkhead box protein O1-A Recombinant
 Forkhead box protein O1-A Antibody
Transcriptional regulator of cell cycle arrest required for cellular stress responses (). May be involved in regulating cellular homeostasis in the eye.
 foxo1a ELISA Kit
 foxo1a Recombinant
 foxo1a Antibody
 foxo1 ELISA Kit
 foxo1 Recombinant
 foxo1 Antibody
 foxO1a.1 ELISA Kit
 foxO1a.1 Recombinant
 foxO1a.1 Antibody
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Forkhead box protein O1-B

 Forkhead box protein O1-B ELISA Kit
 Forkhead box protein O1-B Recombinant
 Forkhead box protein O1-B Antibody
Transcriptional regulator of cell cycle arrest required for cellular stress responses.
 foxo1b ELISA Kit
 foxo1b Recombinant
 foxo1b Antibody
 foxO1a.2 ELISA Kit
 foxO1a.2 Recombinant
 foxO1a.2 Antibody
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Forkhead box protein O3

 Forkhead box protein O3 ELISA Kit
 Forkhead box protein O3 Recombinant
 Forkhead box protein O3 Antibody
FOXO3A: a transcription factors of the forkhead family. Contains 1 fork-head domain. May regulate apoptosis through control of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.

Protein type: Autophagy; DNA-binding; Oncoprotein; Transcription factor

Cellular Component: cytoplasm; cytosol; membrane; mitochondrion; nucleoplasm; nucleus

Molecular Function: beta-catenin binding; chromatin DNA binding; DNA binding; protein binding; protein kinase binding; sequence-specific DNA binding; transcription factor a
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ctivity

Biological Process: aging; antral ovarian follicle growth; brain morphogenesis; DNA damage response, signal transduction by p53 class mediator; glucose homeostasis; initiation of primordial ovarian follicle growth; negative regulation of neuron differentiation; negative regulation of transcription from RNA polymerase II promoter; oocyte maturation; ovulation from ovarian follicle; positive regulation of apoptosis; positive regulation of erythrocyte differentiation; positive regulation of neuron apoptosis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; regulation of translation; tumor necrosis factor-mediated signaling pathway
 Foxo3 ELISA Kit
 Foxo3 Recombinant
 Foxo3 Antibody
 Fkhr2 ELISA Kit
 Fkhr2 Recombinant
 Fkhr2 Antibody
 Foxo3a ELISA Kit
 Foxo3a Recombinant
 Foxo3a Antibody
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Forkhead box protein O4

 Forkhead box protein O4 ELISA Kit
 Forkhead box protein O4 Recombinant
 Forkhead box protein O4 Antibody
Also known as Forkhead box protein O4 (Afxh) (Fork head domain transcription factor AFX1).
FOXO4: transcription factor AFX1 containing 1 fork-head domain. May play a role in the insulin signaling pathway. Involved in acute leukemias by a chromosomal translocation t(X;11)(q13;q23) that involves MLLT7 and MLL/HRX. The result is a rogue activator protein. Two splice-variant isoforms have been described.

Protein type: DNA-binding; Oncoprotein; Transcription factor

Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus

Molecular Function: beta-catenin binding; DNA bind
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ing; enzyme binding; sequence-specific DNA binding; transcription factor activity; transcription factor binding

Biological Process: cell cycle arrest; insulin receptor signaling pathway; mitotic cell cycle G2/M transition DNA damage checkpoint; negative regulation of angiogenesis; negative regulation of cell proliferation; negative regulation of smooth muscle cell differentiation; positive regulation of smooth muscle cell migration; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; stem cell differentiation
 Foxo4 ELISA Kit
 Foxo4 Recombinant
 Foxo4 Antibody
 Afx ELISA Kit
 Afx Recombinant
 Afx Antibody
 Afx1 ELISA Kit
 Afx1 Recombinant
 Afx1 Antibody
 Fkhr3 ELISA Kit
 Fkhr3 Recombinant
 Fkhr3 Antibody
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Forkhead box protein O6

 Forkhead box protein O6 ELISA Kit
 Forkhead box protein O6 Recombinant
 Forkhead box protein O6 Antibody
FOXO6: Transcriptional activator.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 1p34.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: regulation of transcription from RNA polymerase II promoter
 FOXO6 ELISA Kit
 FOXO6 Recombinant
 FOXO6 Antibody
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Forkhead box protein P1

 Forkhead box protein P1 ELISA Kit
 Forkhead box protein P1 Recombinant
 Forkhead box protein P1 Antibody
Transcriptional repressor. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential t
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ranscriptional regulator of B-cell development. Involved in regulation of cardiac muscle cell proliferation. Involved in the columnar organization of spinal motor neurons. Promotes the formation of the lateral motor neuron column (LMC) and the preganglionic motor column (PGC) and is required for respective appropriate motor axon projections. The segment-appropriate generation of spinal chord motor columns requires cooperation with other Hox proteins. Can regulate PITX3 promoter activity; may promote midbrain identity in embryonic stem cell-derived dopamine neurons by regulating PITX3. Negatively regulates the differentiation of T follicular helper cells T(FH)s. Involved in maintainance of hair follicle stem cell quiescence; the function probably involves regulation of FGF18. Represses transcription of various pro-apoptotic genes and cooperates with NF-kappa B-signaling in promoting B-cell expansion by inhibition of caspase-dependent apoptosis. Binds to CSF1R promoter elements and is involved in regulation of monocyte differentiation and macrophage functions; repression of CSF1R in monocytes seems to involve NCOR2 as corepressor. Involved in endothelial cell proliferation, tube formation and migration indicative for a role in angiogenesis; the role in neovascularization seems to implicate suppression of SEMA5B. Can negatively regulate androgen receptor signaling ().
 FOXP1 ELISA Kit
 FOXP1 Recombinant
 FOXP1 Antibody
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Forkhead box protein P1-B

 Forkhead box protein P1-B ELISA Kit
 Forkhead box protein P1-B Recombinant
 Forkhead box protein P1-B Antibody
Transcriptional repressor.
 foxp1b ELISA Kit
 foxp1b Recombinant
 foxp1b Antibody
 foxp1 ELISA Kit
 foxp1 Recombinant
 foxp1 Antibody
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Forkhead box protein P2

 Forkhead box protein P2 ELISA Kit
 Forkhead box protein P2 Recombinant
 Forkhead box protein P2 Antibody
Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels ().
 FOXP2 ELISA Kit
 FOXP2 Recombinant
 FOXP2 Antibody
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Forkhead box protein P3

 Forkhead box protein P3 ELISA Kit
 Forkhead box protein P3 Recombinant
 Forkhead box protein P3 Antibody
Transcriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg). Plays an essential role in maintaining homeostasis of the immune system by allowing the acquisition of full suppressive function and stability of the Treg lineage, and by directly modulating the expansion and function of conventional T-cells. Can act either as a transcriptional repr
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essor or a transcriptional activator depending on its interactions with other transcription factors, histone acetylases and deacetylases. The suppressive activity of Treg involves the coordinate activation of many genes, including CTLA4 and TNFRSF18 by FOXP3 along with repression of genes encoding cytokines such as interleukin-2 (IL2) and interferon-gamma (IFNG). Inhibits cytokine production and T-cell effector function by repressing the activity of two key transcription factors, RELA and NFATC2. Mediates transcriptional repression of IL2 via its association with histone acetylase KAT5 and histone deacetylase HDAC7. Can activate the expression of TNFRSF18, IL2RA and CTLA4 and repress the expression of IL2 and IFNG via its association with transcription factor RUNX1. Inhibits the differentiation of IL17 producing helper T-cells (Th17) by antagonizing RORC function, leading to down-regulation of IL17 expression, favoring Treg development. Inhibits the transcriptional activator activity of RORA. Can repress the expression of IL2 and IFNG via its association with transcription factor IKZF4.
 FOXP3 ELISA Kit
 FOXP3 Recombinant
 FOXP3 Antibody
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Forkhead box protein P4

 Forkhead box protein P4 ELISA Kit
 Forkhead box protein P4 Recombinant
 Forkhead box protein P4 Antibody
Also known as Forkhead box protein P4 (Fork head-related protein-like A).
FOXP4: Transcriptional repressor that represses lung-specific expression. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: nucleus
<
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br>Molecular Function: protein binding
 FOXP4 ELISA Kit
 FOXP4 Recombinant
 FOXP4 Antibody
 FKHLA ELISA Kit
 FKHLA Recombinant
 FKHLA Antibody
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Forkhead box protein Q1

 Forkhead box protein Q1 ELISA Kit
 Forkhead box protein Q1 Recombinant
 Forkhead box protein Q1 Antibody
Also known as Forkhead box protein Q1 (HFH-1l) (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1).
FOXQ1: Plays a role in hair follicle differentiation.

Protein type: DNA-binding

Cellular Component: nucleus

Biological Process: hair follicle morphogenesis
 Foxq1 ELISA Kit
 Foxq1 Recombinant
 Foxq1 Antibody
 Hfh1 ELISA Kit
 Hfh1 Recombinant
 Hfh1 Antibody
 Hfh1l ELISA Kit
 Hfh1l Recombinant
 Hfh1l Antibody
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Forkhead box protein R1

 Forkhead box protein R1 ELISA Kit
 Forkhead box protein R1 Recombinant
 Forkhead box protein R1 Antibody
Also known as Forkhead box protein R1 (Forkhead box protein N5).
FOXR1: 2 isoforms of the human protein are produced by alternative splicing

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: nucleus

Molecular Function: protein binding
 FOXR1 ELISA Kit
 FOXR1 Recombinant
 FOXR1 Antibody
 FOXN5 ELISA Kit
 FOXN5 Recombinant
 FOXN5 Antibody
 DLNB13 ELISA Kit
 DLNB13 Recombinant
 DLNB13 Antibody
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Forkhead box protein R2

 Forkhead box protein R2 ELISA Kit
 Forkhead box protein R2 Recombinant
 Forkhead box protein R2 Antibody
Also known as Forkhead box protein R2 (Forkhead box protein N6).
FOXR2:

Protein type: DNA-binding

Cellular Component: nucleus
 Foxr2 ELISA Kit
 Foxr2 Recombinant
 Foxr2 Antibody
 Foxn6 ELISA Kit
 Foxn6 Recombinant
 Foxn6 Antibody
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Forkhead box protein S1

 Forkhead box protein S1 ELISA Kit
 Forkhead box protein S1 Recombinant
 Forkhead box protein S1 Antibody
Also known as Forkhead box protein S1 (Forkhead-like 18 protein) (Forkhead-related transcription factor 10) (FREAC-10).
FKHL18: Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 20q11.21

Cellular Component: nucleus

Molecular Function: DNA binding; transcription factor activity

Biological Process: blood vessel development; negative regulation of transcription factor activity; ne
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gative regulation of transcription, DNA-dependent
 FOXS1 ELISA Kit
 FOXS1 Recombinant
 FOXS1 Antibody
 FKHL18 ELISA Kit
 FKHL18 Recombinant
 FKHL18 Antibody
 FREAC10 ELISA Kit
 FREAC10 Recombinant
 FREAC10 Antibody
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Proteins Root Name Listing
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