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Formamidopyrimidine-DNA glycosylase

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Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Can process efficiently 4,6-diamino-5-formamidopyrimidine (FapyA), 2,6-diamino-4- hydroxy-5-formamidopyrimidine (FapyG) and the further oxidation products of 8-oxoguanine (8-oxoG), such as guanidinohydantoin and spiroiminodihydantoin. Has marginal activity towards 8-oxoG. Has AP (apurinic/apyrimidinic) lyase activity. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Below are the list of possible Formamidopyrimidine-DNA glycosylase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Formamidopyrimidine-DNA glycosylase

 Formamidopyrimidine-DNA glycosylase ELISA Kit
 Formamidopyrimidine-DNA glycosylase Recombinant
 Formamidopyrimidine-DNA glycosylase Antibody
Also known as Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase FPG1) (Formamidopyrimidine-DNA glycosylase 1) (AtFPG-1) (Formamidopyrimidine-DNA glycosylase 2) (AtFPG-2) (Protein MutM homo.
Encodes one of the splice variants of Arabidopsis thaliana MutM homolog. Encodes a formamidopyrimidine-DNA glycosylase that has abasic lyase activity and is able to nick double- stranded oligonucleotides containing 8-oxo-7,8-dihydroguanine (8-oxoG) in vitro.
 FPG1 ELISA Kit
 FPG1 Recombinant
 FPG1 Antibody
 FPG2 ELISA Kit
 FPG2 Recombinant
 FPG2 Antibody
 At1g52500 ELISA Kit
 At1g52500 Recombinant
 At1g52500 Antibody
 F6D8.28 ELISA Kit
 F6D8.28 Recombinant
 F6D8.28 Antibody
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Formamidopyrimidine-DNA glycosylase 1

 Formamidopyrimidine-DNA glycosylase 1 ELISA Kit
 Formamidopyrimidine-DNA glycosylase 1 Recombinant
 Formamidopyrimidine-DNA glycosylase 1 Antibody
Also known as Formamidopyrimidine-DNA glycosylase 1 (Fapy-DNA glycosylase 1) (DNA-(apurinic or apyrimidinic site) lyase MutM 1) (AP lyase MutM 1).
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG) when paired with C, G or T, as well as methyl-faPy (formanidopyrimidine residues) in poly(dG-dC) and spiroiminodihydantoin:C base pairs. Unlike its E.coli ortholog has no activity on 8-oxoG:A. Has AP (apurinic/apyrimi
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dinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Cleaves ssDNA containing an AP site. Complements the H2O2 sensitivity of an M.smegmatis fpg disruption mutant; upon expression in M.smegmatis excises 8-oxoG from dsDNA.
 fpg1 ELISA Kit
 fpg1 Recombinant
 fpg1 Antibody
 mutM ELISA Kit
 mutM Recombinant
 mutM Antibody
 Rv2924c ELISA Kit
 Rv2924c Recombinant
 Rv2924c Antibody
 MTCY338.13c ELISA Kit
 MTCY338.13c Recombinant
 MTCY338.13c Antibody
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