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Formimidoyltransferase-cyclodeaminase

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Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity).

Below are the list of possible Formimidoyltransferase-cyclodeaminase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Formimidoyltransferase-cyclodeaminase

 Formimidoyltransferase-cyclodeaminase ELISA Kit
 Formimidoyltransferase-cyclodeaminase Recombinant
 Formimidoyltransferase-cyclodeaminase Antibody
Also known as Formimidoyltransferase-cyclodeaminase (58 kDa microtubule-binding protein) (Formiminotransferase-cyclodeaminase) (FTCD).
FTCD: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. Defects in FTCD are the cause of glutamate formiminotransferase deficiency (FIGLU-URIA); also kno
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wn as formiminoglutamicaciduria (FIGLU-uria). It is an autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - histidine; Cofactor and Vitamin Metabolism - one carbon pool by folate; EC 2.1.2.5; EC 4.3.1.4; Lyase; Methyltransferase

Cellular Component: cytosol; endoplasmic reticulum; ER-Golgi intermediate compartment; Golgi apparatus; Golgi membrane; smooth endoplasmic reticulum membrane

Molecular Function: formimidoyltetrahydrofolate cyclodeaminase activity; formimidoyltransferase activity; glutamate formimidoyltransferase activity; intermediate filament binding; microtubule binding

Biological Process: cytoskeleton organization and biogenesis
 Ftcd ELISA Kit
 Ftcd Recombinant
 Ftcd Antibody
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