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Four and a half LIM domains protein

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May have an involvement in muscle development or hypertrophy. Isoform 2 binds to RBP-J and plays a negative regulatory role in the RBP-J-mediated transcription in mammalian systems (By similarity).

Below are the list of possible Four and a half LIM domains protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Four and a half LIM domains protein 1

 Four and a half LIM domains protein 1 ELISA Kit
 Four and a half LIM domains protein 1 Recombinant
 Four and a half LIM domains protein 1 Antibody
Also known as Four and a half LIM domains protein 1 (FHL-1).
FHL1: May have an involvement in muscle development or hypertrophy. Defects in FHL1 are the cause of X-linked dominant scapuloperoneal myopathy (SPM). Scapuloperoneal syndrome (SPS) was initially described more than 120 years ago by Jules Broussard as 'une forme hereditaire d'atrophie musculaire progressive' beginning in the lower leg
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s and affecting the shoulder region earlier and more severely than distal arm. The etiology of this condition remains unclear. Defects in FHL1 are the cause of X-linked myopathy with postural muscle atrophy (XMPMA). Myopathies are inherited muscle disorders characterized by weakness and atrophy of voluntary skeletal muscle, and several types of myopathy also show involvement of cardiac muscle. XMPMA is a distinct form of adult-onset X-linked recessive myopathy with several features in common with other myopathies, but the presentation of a pseudoathletic phenotype, scapuloperoneal weakness, and bent spine is unique and might render the clinical phenotype distinguishable from other myopathies. Defects in FHL1 are the cause of X-linked severe early- onset reducing body myopathy (RBM). RBM is a rare muscle disorder causing progressive muscular weakness and characteristic intracytoplasmic inclusions in myofibers. Clinical presentations of RBM have ranged from early onset fatal to childhood onset to adult onset cases. Defects in FHL1 are the cause of X-linked childhood-onset reducing body myopathy (CO-RBM). This disorder is allelic to severe early-onset reducing body myopathy (RBM). 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation

Cellular Component: cytoplasm; focal adhesion; nucleus; plasma membrane

Biological Process: negative regulation of cell growth; positive regulation of potassium ion transport
 Fhl1 ELISA Kit
 Fhl1 Recombinant
 Fhl1 Antibody
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Four and a half LIM domains protein 2

 Four and a half LIM domains protein 2 ELISA Kit
 Four and a half LIM domains protein 2 Recombinant
 Four and a half LIM domains protein 2 Antibody
Also known as Four and a half LIM domains protein 2 (FHL-2).
May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetyl
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ation ().
 FHL2 ELISA Kit
 FHL2 Recombinant
 FHL2 Antibody
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Four and a half LIM domains protein 3

 Four and a half LIM domains protein 3 ELISA Kit
 Four and a half LIM domains protein 3 Recombinant
 Four and a half LIM domains protein 3 Antibody
Also known as Four and a half LIM domains protein 3 (FHL-3).
 FHL3 ELISA Kit
 FHL3 Recombinant
 FHL3 Antibody
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Four and a half LIM domains protein 5

 Four and a half LIM domains protein 5 ELISA Kit
 Four and a half LIM domains protein 5 Recombinant
 Four and a half LIM domains protein 5 Antibody
Also known as Four and a half LIM domains protein 5 (FHL-5).
May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner ().
 FHL5 ELISA Kit
 FHL5 Recombinant
 FHL5 Antibody
 QtsA-15776 ELISA Kit
 QtsA-15776 Recombinant
 QtsA-15776 Antibody
 QtsA-20333 ELISA Kit
 QtsA-20333 Recombinant
 QtsA-20333 Antibody
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