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Fumigaclavine A dimethylallyltransferase

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Fumigaclavine A dimethylallyltransferase; part of the gene cluster that mediates the biosynthesis of fumiclavanine C, a fungal ergot alkaloid .

Below are the list of possible Fumigaclavine A dimethylallyltransferase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Fumigaclavine A dimethylallyltransferase easL

 Fumigaclavine A dimethylallyltransferase easL ELISA Kit
 Fumigaclavine A dimethylallyltransferase easL Recombinant
 Fumigaclavine A dimethylallyltransferase easL Antibody
Also known as Fumigaclavine A dimethylallyltransferase easL (Ergot alkaloid synthesis protein L).
Fumigaclavine A dimethylallyltransferase; part of the gene cluster that mediates the biosynthesis of fumiclavanine C, a fungal ergot alkaloid (PubMed:15933009, PubMed:22453123). DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:15870460). The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methio
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nine, resulting in the formation of 4-dimethylallyl-L-abrine (). The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by EasD in the presence of NAD+, resulting in the formation of chanoclavine-I aldehyde (PubMed:20039019, PubMed:20526482, PubMed:21409592). EasA reduces chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde that spontaneously dehydrates to form 6,8-dimethyl-6,7-didehydroergoline (PubMed:20526482). EasG then catalyzes the reduction of 6,8-dimethyl-6,7-didehydroergoline to form festuclavine (PubMed:20526482). Hydrolysis of festuclavine by easM then leads to the formation of fumigaclavine B which is in turn acetylated by easN to fumigaclavine A (PubMed:26972831). Finally, easL catalyzes the conversion of fumigaclavine A into fumigaclavine C by attaching a dimethylallyl moiety to C-2 of the indole nucleus (PubMed:19672909).
 easL ELISA Kit
 easL Recombinant
 easL Antibody
 fgaPT1 ELISA Kit
 fgaPT1 Recombinant
 fgaPT1 Antibody
 AFUA_2G17990 ELISA Kit
 AFUA_2G17990 Recombinant
 AFUA_2G17990 Antibody
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