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G-protein coupled receptor

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Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).

Below are the list of possible G-protein coupled receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

G protein-coupled receptor 161

 G protein-coupled receptor 161 ELISA Kit
 G protein-coupled receptor 161 Recombinant
 G protein-coupled receptor 161 Antibody
Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In pre
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sence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown ().
 GPR161 ELISA Kit
 GPR161 Recombinant
 GPR161 Antibody
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G protein-coupled receptor GPR1

 G protein-coupled receptor GPR1 ELISA Kit
 G protein-coupled receptor GPR1 Recombinant
 G protein-coupled receptor GPR1 Antibody
Seems to associate with GPA2 and act as G protein-coupled receptor that senses glucose and controls filamentous growth. It acts upstream of adenylate cyclase and is required for glucose activation of cAMP synthesis in concert with a glucose phosphorylation-dependent mechanism.
 GPR1 ELISA Kit
 GPR1 Recombinant
 GPR1 Antibody
 YDL035C ELISA Kit
 YDL035C Recombinant
 YDL035C Antibody
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G-protein coupled receptor

 G-protein coupled receptor ELISA Kit
 G-protein coupled receptor Recombinant
 G-protein coupled receptor Antibody
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G-protein coupled receptor 1

 G-protein coupled receptor 1 ELISA Kit
 G-protein coupled receptor 1 Recombinant
 G-protein coupled receptor 1 Antibody
encodes a protein similar to G-coupled receptor with 7 transmembrane regions. Overexpression studies suggest this gene is involved in dormancy and flowering. Reduction of expression results in decreased sensitivity to cytokinin.
 GCR1 ELISA Kit
 GCR1 Recombinant
 GCR1 Antibody
 At1g48270 ELISA Kit
 At1g48270 Recombinant
 At1g48270 Antibody
 F11A17.17 ELISA Kit
 F11A17.17 Recombinant
 F11A17.17 Antibody
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G-protein coupled receptor 12

 G-protein coupled receptor 12 ELISA Kit
 G-protein coupled receptor 12 Recombinant
 G-protein coupled receptor 12 Antibody
GPR12: Promotes neurite outgrowth and blocks myelin inhibition in neurons. Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 13q12

Cellular Comp
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onent: integral to plasma membrane
 GPR12 ELISA Kit
 GPR12 Recombinant
 GPR12 Antibody
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G-protein coupled receptor 126

 G-protein coupled receptor 126 ELISA Kit
 G-protein coupled receptor 126 Recombinant
 G-protein coupled receptor 126 Antibody
G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane. Couples to G(i)-proteins as well as G(s)-proteins (PubMed:25118328). Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PubMed:19745155). Plays also a role in inner ear development (PubMed:24067352).
 gpr126 ELISA Kit
 gpr126 Recombinant
 gpr126 Antibody
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G-protein coupled receptor 143

 G-protein coupled receptor 143 ELISA Kit
 G-protein coupled receptor 143 Recombinant
 G-protein coupled receptor 143 Antibody
Also known as G-protein coupled receptor 143 (MOA1) (Ocular albinism type 1 protein homolog).
GPR143: Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca(2+) influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand- dependent signaling occurs through a G(q)-mediated pathway
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in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Plays also a role as an intracellular G protein-coupled receptor involved in melanosome biogenesis, organization and transport. Defects in GPR143 are the cause of albinism ocular type 1 (OA1); also known as Nettleship-Falls type ocular albinism. Form of albinism affecting only the eye. Pigment of the hair and skin is normal or only slightly diluted. Eyes may be severely affected with photophobia and reduced visual acuity. Nystagmus or strabismus are often associated. The irides and fundus are depigmented. Defects in GPR143 are the cause of Nystagmus congenital X-linked type 6 (NYS6). It is a condition defined as conjugated, spontaneous and involuntary ocular oscillations that appear at birth or during the first three months of life. Other associated features may include mildly decreased visual acuity, strabismus, astigmatism, and occasionally head nodding. Belongs to the G-protein coupled receptor OA family.

Protein type: GPCR, OA family; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: apical plasma membrane; Golgi apparatus; integral to membrane; lysosomal membrane; melanosome; melanosome membrane; plasma membrane

Molecular Function: dopamine binding; G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; melanosome localization; melanosome organization and biogenesis; melanosome transport; phosphoinositide-mediated signaling; regulation of calcium-mediated signaling
 Gpr143 ELISA Kit
 Gpr143 Recombinant
 Gpr143 Antibody
 Oa1 ELISA Kit
 Oa1 Recombinant
 Oa1 Antibody
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G-protein coupled receptor 15

 G-protein coupled receptor 15 ELISA Kit
 G-protein coupled receptor 15 Recombinant
 G-protein coupled receptor 15 Antibody
GPR15: Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: cytoplasm

Molecular Function: G-protein coupled receptor activity
 Gpr15 ELISA Kit
 Gpr15 Recombinant
 Gpr15 Antibody
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G-protein coupled receptor 161

 G-protein coupled receptor 161 ELISA Kit
 G-protein coupled receptor 161 Recombinant
 G-protein coupled receptor 161 Antibody
Key negative regulator of Shh signaling during neural tube development. Recruited to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of gli3 into gli3r and repress the Shh signaling. In presence of shh, it is removed from primary cilia, preventing its activity and allow
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ing activation of the Shh signaling ().
 gpr161 ELISA Kit
 gpr161 Recombinant
 gpr161 Antibody
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G-protein coupled receptor 182

 G-protein coupled receptor 182 ELISA Kit
 G-protein coupled receptor 182 Recombinant
 G-protein coupled receptor 182 Antibody
GPR182: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 12q13.3

Molecular Function: G-protein coupled receptor activity; transmembrane receptor activity

Biological Process: cell surface receptor linked signal
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transduction
 GPR182 ELISA Kit
 GPR182 Recombinant
 GPR182 Antibody
 ADMR ELISA Kit
 ADMR Recombinant
 ADMR Antibody
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G-protein coupled receptor 183

 G-protein coupled receptor 183 ELISA Kit
 G-protein coupled receptor 183 Recombinant
 G-protein coupled receptor 183 Antibody
G-protein coupled receptor expressed in lymphocytes that acts as a chemotactic receptor for B-cells, T-cells, splenic dendritic cells, monocytes/macrophages and astrocytes (). Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols (). Mediates cell positioning and movement of a number of cells by binding the 7-alpha,25-OHC ligand that forms a chemotact
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ic gradient (). Binding of 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses (). Guides B-cell movement along the B-cell zone-T-cell zone boundary and later to interfollicular and outer follicular regions (). Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (). Collaborates with CXCR5 to mediate B-cell migration; probably by forming a heterodimer with CXCR5 that affects the interaction between of CXCL13 and CXCR5 (). Also acts as a chemotactic receptor for some T-cells upon binding to 7-alpha,25-OHC ligand (). Promotes follicular helper T (Tfh) cells differentiation by positioning activated T-cells at the follicle-T-zone interface, promoting contact of newly activated CD4 T-cells with activated dendritic cells and exposing them to Tfh-cell-promoting inducible costimulator (ICOS) ligand (). Expression in splenic dendritic cells is required for their homeostasis, localization and ability to induce B- and T-cell responses: GPR183 acts as a chemotactic receptor in dendritic cells that mediates the accumulation of CD4+ dendritic cells in bridging channels (). Regulates migration of astrocytes and is involved in communication between astrocytes and macrophages (). Promotes osteoclast precursor migration to bone surfaces (). Signals constitutively through G(i)-alpha, but not G(s)-alpha or G(q)-alpha (). Signals constitutively also via MAPK1/3 (ERK1/2) ().
 GPR183 ELISA Kit
 GPR183 Recombinant
 GPR183 Antibody
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G-protein coupled receptor 183-A

 G-protein coupled receptor 183-A ELISA Kit
 G-protein coupled receptor 183-A Recombinant
 G-protein coupled receptor 183-A Antibody
G-protein coupled receptor expressed in lymphocytes that acts as a chemotactic receptor for B-cells, T-cells, splenic dendritic cells, monocytes/macrophages and astrocytes (). Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols (). Mediates cell positioning and movement of a number of cells by binding the 7-alpha,25-OHC ligand that forms a chemotactic gradient (). Binding of 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses ().
 gpr183a ELISA Kit
 gpr183a Recombinant
 gpr183a Antibody
 gpr183 ELISA Kit
 gpr183 Recombinant
 gpr183 Antibody
 zgc:165579 ELISA Kit
 zgc:165579 Recombinant
 zgc:165579 Antibody
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G-protein coupled receptor 183-B

 G-protein coupled receptor 183-B ELISA Kit
 G-protein coupled receptor 183-B Recombinant
 G-protein coupled receptor 183-B Antibody
Probable receptor for oxysterols that plays a central role during humoral immunity. Promotes activated B-cell localization in the outer follicle and interfollicular regions ().
 gpr183b ELISA Kit
 gpr183b Recombinant
 gpr183b Antibody
 si:dkey-22o12.5 ELISA Kit
 si:dkey-22o12.5 Recombinant
 si:dkey-22o12.5 Antibody
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G-protein coupled receptor 20

 G-protein coupled receptor 20 ELISA Kit
 G-protein coupled receptor 20 Recombinant
 G-protein coupled receptor 20 Antibody
GPR20: Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: cell; integral to plasma membrane; receptor complex

Molecular Function: G-protein coupled receptor activity
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r>Biological Process: elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of Rho protein signal transduction
 Gpr20 ELISA Kit
 Gpr20 Recombinant
 Gpr20 Antibody
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G-protein coupled receptor 26

 G-protein coupled receptor 26 ELISA Kit
 G-protein coupled receptor 26 Recombinant
 G-protein coupled receptor 26 Antibody
GPR26: Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of
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Human Ortholog: 10q26.13

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein signaling, adenylate cyclase activating pathway; regulation of protein stability
 GPR26 ELISA Kit
 GPR26 Recombinant
 GPR26 Antibody
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G-protein coupled receptor 3

 G-protein coupled receptor 3 ELISA Kit
 G-protein coupled receptor 3 Recombinant
 G-protein coupled receptor 3 Antibody
Also known as G-protein coupled receptor 3 (ACCA orphan receptor).
GPR3: Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Has a potential role in modulating a number of brain functions, including behavioral responses to stress, amyloid-beta peptide generation in neurons and neurite outgrowth. Maintains also meiotic arrest in oocytes. Belongs to the G-protein c
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oupled receptor 1 family.

Protein type: Cell cycle regulation; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 1p36.1-p35

Cellular Component: integral to plasma membrane

Molecular Function: protein binding

Biological Process: G-protein signaling, adenylate cyclase activating pathway
 GPR3 ELISA Kit
 GPR3 Recombinant
 GPR3 Antibody
 ACCA ELISA Kit
 ACCA Recombinant
 ACCA Antibody
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G-protein coupled receptor 35

 G-protein coupled receptor 35 ELISA Kit
 G-protein coupled receptor 35 Recombinant
 G-protein coupled receptor 35 Antibody
Also known as G-protein coupled receptor 35 (Kynurenic acid receptor) (KYNA receptor).
GPR35: Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. Belongs to the G-protein coupled receptor 1 family.

Pro
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tein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: C-X-C chemokine receptor activity; chemokine receptor activity; G-protein coupled receptor activity

Biological Process: cytoskeleton organization and biogenesis; elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein coupled receptor protein signaling pathway; macrophage chemotaxis; positive regulation of Rho protein signal transduction
 Gpr35 ELISA Kit
 Gpr35 Recombinant
 Gpr35 Antibody
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G-protein coupled receptor 39

 G-protein coupled receptor 39 ELISA Kit
 G-protein coupled receptor 39 Recombinant
 G-protein coupled receptor 39 Antibody
GPR39: Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death. Belongs to the G-protein coupled receptor 1 family.
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r>Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Biological Process: adult feeding behavior; cholesterol homeostasis; diet induced thermogenesis; glucose homeostasis; positive regulation of insulin secretion; positive regulation of release of sequestered calcium ion into cytosol; regulation of lipid metabolic process; regulation of membrane potential
 Gpr39 ELISA Kit
 Gpr39 Recombinant
 Gpr39 Antibody
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G-protein coupled receptor 4

 G-protein coupled receptor 4 ELISA Kit
 G-protein coupled receptor 4 Recombinant
 G-protein coupled receptor 4 Antibody
GPR4: Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: integral to plasma membrane

Molecular Function: G-protein coupled re
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ceptor activity

Biological Process: angiogenesis involved in wound healing; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein coupled receptor protein signaling pathway; negative regulation of angiogenesis; positive regulation of Rho protein signal transduction; response to acidity
 Gpr4 ELISA Kit
 Gpr4 Recombinant
 Gpr4 Antibody
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G-protein coupled receptor 42

 G-protein coupled receptor 42 ELISA Kit
 G-protein coupled receptor 42 Recombinant
 G-protein coupled receptor 42 Antibody
GPR42: May act as a receptor for short chain fatty acids, such as propionate. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: integral to plasma membrane

Molecular Function: G-protein coupled recep
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tor activity

Biological Process: G-protein coupled receptor protein signaling pathway
 GPR42 ELISA Kit
 GPR42 Recombinant
 GPR42 Antibody
 GPR42P ELISA Kit
 GPR42P Recombinant
 GPR42P Antibody
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G-protein coupled receptor 54

 G-protein coupled receptor 54 ELISA Kit
 G-protein coupled receptor 54 Recombinant
 G-protein coupled receptor 54 Antibody
Receptor speculated to be essential for sexual development. May regulate gonadotropin-releasing hormone (GnRH) secretion. The receptor expression could be a "stop signal" for GnRH1, GnRH2, and GnRH3 neuronal migration, leading to suppression of cell growth and modulation of GnRH secretion, which is important for normal sexual development.
 gpr54 ELISA Kit
 gpr54 Recombinant
 gpr54 Antibody
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G-protein coupled receptor 55

 G-protein coupled receptor 55 ELISA Kit
 G-protein coupled receptor 55 Recombinant
 G-protein coupled receptor 55 Antibody
GPR55: May be involved in hyperalgesia associated with inflammatory and neuropathic pain. Receptor for L- alpha-lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. Putative cannabinoid receptor. May play a role in bone physiology by regulating osteoclast number and function. Belongs to the G-protein coupled receptor
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1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: integral to plasma membrane

Molecular Function: cannabinoid receptor activity

Biological Process: bone resorption; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); negative regulation of osteoclast differentiation; phospholipase C activation; positive regulation of Rho protein signal transduction
 Gpr55 ELISA Kit
 Gpr55 Recombinant
 Gpr55 Antibody
 Gm218 ELISA Kit
 Gm218 Recombinant
 Gm218 Antibody
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G-protein coupled receptor 6

 G-protein coupled receptor 6 ELISA Kit
 G-protein coupled receptor 6 Recombinant
 G-protein coupled receptor 6 Antibody
Also known as G-protein coupled receptor 6 (Sphingosine 1-phosphate receptor GPR6).
GPR6: Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor
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, GPCR

Biological Process: elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway
 Gpr6 ELISA Kit
 Gpr6 Recombinant
 Gpr6 Antibody
 Cnl3 ELISA Kit
 Cnl3 Recombinant
 Cnl3 Antibody
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G-protein coupled receptor 74

 G-protein coupled receptor 74 ELISA Kit
 G-protein coupled receptor 74 Recombinant
 G-protein coupled receptor 74 Antibody
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G-protein coupled receptor 78

 G-protein coupled receptor 78 ELISA Kit
 G-protein coupled receptor 78 Recombinant
 G-protein coupled receptor 78 Antibody
GPR78: Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of
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Human Ortholog: 4p16.1

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein signaling, adenylate cyclase activating pathway
 GPR78 ELISA Kit
 GPR78 Recombinant
 GPR78 Antibody
 UNQ5925/PRO19818 ELISA Kit
 UNQ5925/PRO19818 Recombinant
 UNQ5925/PRO19818 Antibody
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G-protein coupled receptor 84

 G-protein coupled receptor 84 ELISA Kit
 G-protein coupled receptor 84 Recombinant
 G-protein coupled receptor 84 Antibody
GPR84: Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important ro
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les in processes from fatty acid metabolism to regulation of the immune system. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Receptor, GPCR

Cellular Component: integral to plasma membrane; receptor complex

Molecular Function: peptide receptor activity, G-protein coupled

Biological Process: G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); neuropeptide signaling pathway
 Gpr84 ELISA Kit
 Gpr84 Recombinant
 Gpr84 Antibody
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G-protein coupled receptor 87

 G-protein coupled receptor 87 ELISA Kit
 G-protein coupled receptor 87 Recombinant
 G-protein coupled receptor 87 Antibody
GPR87: Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: integral to plasma membrane

Molecular Function: purinergic nucleotide receptor activit
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y, G-protein coupled
 Gpr87 ELISA Kit
 Gpr87 Recombinant
 Gpr87 Antibody
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G-protein coupled receptor 98

 G-protein coupled receptor 98 ELISA Kit
 G-protein coupled receptor 98 Recombinant
 G-protein coupled receptor 98 Antibody
Also known as G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1).
GPR98: Receptor that may have an important role in the development of the central nervous system. Defects in GPR98 are the cause of Usher syndrome type 2C (USH2C). USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa with sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndr
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ome type 2 (USH2) and Usher syndrome type 3 (USH3). USH2 is characterized by congenital mild hearing impairment with normal vestibular responses. Defects in GPR98 may be a cause of familial febrile convulsions type 4 (FEB4); also known as familial febrile seizures 4. Febrile convulsions are seizures associated with febrile episodes in childhood without any evidence of intracranial infection or defined pathologic or traumatic cause. It is a common condition, affecting 2-5% of children aged 3 months to 5 years. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 5q13

Cellular Component: cell surface; cytoplasm; receptor complex

Molecular Function: calcium ion binding; protein binding

Biological Process: maintenance of organ identity; neurological system process; photoreceptor cell maintenance; sensory perception of light stimulus; sensory perception of sound

Disease: Febrile Seizures, Familial, 4; Usher Syndrome, Type Iic
 GPR98 ELISA Kit
 GPR98 Recombinant
 GPR98 Antibody
 KIAA0686 ELISA Kit
 KIAA0686 Recombinant
 KIAA0686 Antibody
 KIAA1943 ELISA Kit
 KIAA1943 Recombinant
 KIAA1943 Antibody
 MASS1 ELISA Kit
 MASS1 Recombinant
 MASS1 Antibody
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G-protein coupled receptor A5

 G-protein coupled receptor A5 ELISA Kit
 G-protein coupled receptor A5 Recombinant
 G-protein coupled receptor A5 Antibody
Acts as a viral G-protein coupled receptor that constitutively activates host alphai-type G-proteins, thereby inhibiting host forskolin-triggered CREB activation.
 A5 ELISA Kit
 A5 Recombinant
 A5 Antibody
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G-protein coupled receptor aex-2

 G-protein coupled receptor aex-2 ELISA Kit
 G-protein coupled receptor aex-2 Recombinant
 G-protein coupled receptor aex-2 Antibody
Also known as G-protein coupled receptor aex-2 (Aboc, expulsion defective protein 2).
G-protein coupled receptor for the nlp-40 neuropeptide (PubMed:23583549). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (PubMed:23583549). Plays a role in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seco
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nds (PubMed:18852466, PubMed:23583549). Specifically, acts in GABAergic neurons, such as AVL and DVB, to control the expulsion step of defecation (PubMed:18852466, PubMed:23583549). Required for fatty acid uptake and metabolism by intestinal cells and therefore regulates the levels of triglycerides in the intestine (PubMed:25849533).
 aex-2 ELISA Kit
 aex-2 Recombinant
 aex-2 Antibody
 T14B1.2 ELISA Kit
 T14B1.2 Recombinant
 T14B1.2 Antibody
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G-protein coupled receptor BILF1

 G-protein coupled receptor BILF1 ELISA Kit
 G-protein coupled receptor BILF1 Recombinant
 G-protein coupled receptor BILF1 Antibody
Constitutively active G protein-coupled receptor that plays a role in the modulation of host immunity. As a consequence of its constitutive activity, mediates host CXCR4 inhibition. Enhances degradation of host major histocompatibility complex class I antigens via lysosomes. Targets also newly synthesized MHC-I/peptide complexes en route to the host cell surface. Inhibits the host EIF2AK2/PKR phos
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phorylation.
 BILF1 ELISA Kit
 BILF1 Recombinant
 BILF1 Antibody
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G-protein coupled receptor daf-37

 G-protein coupled receptor daf-37 ELISA Kit
 G-protein coupled receptor daf-37 Recombinant
 G-protein coupled receptor daf-37 Antibody
Also known as G-protein coupled receptor daf-37 (Abnormal dauer formation protein 37).
G-protein coupled receptor (GPCR) that forms a heterodimer with daf-38 to control dauer formation and behavior (PubMed:22665789, PubMed:23509272). Receptor for the ascaroside pheromone ascr#2 (PubMed:22665789). Required for the response to dauer inducing pheromones, specifically the ascaroside ascr#2 (PubMed:
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22665789, PubMed:23509272). May serve neuronal specific roles in response to ascr#2 with expression in ASI neurons controlling dauer formation in larvae, and expression in ASK neurons playing a role in longevity and hermaphrodite repulsion (PubMed:22665789, PubMed:23509272). May function upstream of the daf-11, daf-7 and daf-2 signaling pathways (PubMed:22665789).
 daf-37 ELISA Kit
 daf-37 Recombinant
 daf-37 Antibody
 C30B5.5 ELISA Kit
 C30B5.5 Recombinant
 C30B5.5 Antibody
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G-protein coupled receptor daf-38

 G-protein coupled receptor daf-38 ELISA Kit
 G-protein coupled receptor daf-38 Recombinant
 G-protein coupled receptor daf-38 Antibody
Also known as G-protein coupled receptor daf-38 (Abnormal dauer formation protein 38).
G-protein coupled receptor (GPCR) that forms a heterodimer with daf-37 to control dauer formation and behavior. Required for the response to dauer inducing pheromones such as the ascarosides ascr#2, ascr#3 and ascr#5.
 daf-38 ELISA Kit
 daf-38 Recombinant
 daf-38 Antibody
 Y105C5A.23 ELISA Kit
 Y105C5A.23 Recombinant
 Y105C5A.23 Antibody
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G-protein coupled receptor E1

 G-protein coupled receptor E1 ELISA Kit
 G-protein coupled receptor E1 Recombinant
 G-protein coupled receptor E1 Antibody
 E1 ELISA Kit
 E1 Recombinant
 E1 Antibody
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G-protein coupled receptor E6

 G-protein coupled receptor E6 ELISA Kit
 G-protein coupled receptor E6 Recombinant
 G-protein coupled receptor E6 Antibody
 E6 ELISA Kit
 E6 Recombinant
 E6 Antibody
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G-protein coupled receptor GRL101

 G-protein coupled receptor GRL101 ELISA Kit
 G-protein coupled receptor GRL101 Recombinant
 G-protein coupled receptor GRL101 Antibody
Might directly transduce signals carried by large extracellular lipoprotein complexes into neuronal events.
Table BarTOPTable Bar
 

G-protein coupled receptor homolog C3

 G-protein coupled receptor homolog C3 ELISA Kit
 G-protein coupled receptor homolog C3 Recombinant
 G-protein coupled receptor homolog C3 Antibody
 C3L ELISA Kit
 C3L Recombinant
 C3L Antibody
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G-protein coupled receptor homolog ECRF3

 G-protein coupled receptor homolog ECRF3 ELISA Kit
 G-protein coupled receptor homolog ECRF3 Recombinant
 G-protein coupled receptor homolog ECRF3 Antibody
May be highly relevant to the process of cellular transformation and rapid T-cell proliferation effected by HVS during latent infections of T-cells in susceptible hosts.
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G-protein coupled receptor homolog FPV021

 G-protein coupled receptor homolog FPV021 ELISA Kit
 G-protein coupled receptor homolog FPV021 Recombinant
 G-protein coupled receptor homolog FPV021 Antibody
 FPV021 ELISA Kit
 FPV021 Recombinant
 FPV021 Antibody
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G-protein coupled receptor homolog FPV027

 G-protein coupled receptor homolog FPV027 ELISA Kit
 G-protein coupled receptor homolog FPV027 Recombinant
 G-protein coupled receptor homolog FPV027 Antibody
 FPV027 ELISA Kit
 FPV027 Recombinant
 FPV027 Antibody
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G-protein coupled receptor homolog FPV206

 G-protein coupled receptor homolog FPV206 ELISA Kit
 G-protein coupled receptor homolog FPV206 Recombinant
 G-protein coupled receptor homolog FPV206 Antibody
 FPV206 ELISA Kit
 FPV206 Recombinant
 FPV206 Antibody
Table BarTOPTable Bar
 

G-protein coupled receptor homolog K2

 G-protein coupled receptor homolog K2 ELISA Kit
 G-protein coupled receptor homolog K2 Recombinant
 G-protein coupled receptor homolog K2 Antibody
Putative chemokine receptor.
 K2R ELISA Kit
 K2R Recombinant
 K2R Antibody
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G-protein coupled receptor homolog M33

 G-protein coupled receptor homolog M33 ELISA Kit
 G-protein coupled receptor homolog M33 Recombinant
 G-protein coupled receptor homolog M33 Antibody
Plays an important role in vivo, in particular in the dissemination to or replication in the salivary gland.
Table BarTOPTable Bar
 

G-protein coupled receptor homolog Q2/3L

 G-protein coupled receptor homolog Q2/3L ELISA Kit
 G-protein coupled receptor homolog Q2/3L Recombinant
 G-protein coupled receptor homolog Q2/3L Antibody
Putative chemokine receptor.
 Q2/3L ELISA Kit
 Q2/3L Recombinant
 Q2/3L Antibody
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G-protein coupled receptor homolog R33

 G-protein coupled receptor homolog R33 ELISA Kit
 G-protein coupled receptor homolog R33 Recombinant
 G-protein coupled receptor homolog R33 Antibody
Plays an important role in vivo, in particular in the dissemination to or replication in the salivary gland.
Table BarTOPTable Bar
 

G-protein coupled receptor homolog U12

 G-protein coupled receptor homolog U12 ELISA Kit
 G-protein coupled receptor homolog U12 Recombinant
 G-protein coupled receptor homolog U12 Antibody
Probable G-protein coupled receptor.
 U12 ELISA Kit
 U12 Recombinant
 U12 Antibody
 P1RF1 ELISA Kit
 P1RF1 Recombinant
 P1RF1 Antibody
Table BarTOPTable Bar
 

G-protein coupled receptor homolog U51

 G-protein coupled receptor homolog U51 ELISA Kit
 G-protein coupled receptor homolog U51 Recombinant
 G-protein coupled receptor homolog U51 Antibody
 U51 ELISA Kit
 U51 Recombinant
 U51 Antibody
 XKRF1 ELISA Kit
 XKRF1 Recombinant
 XKRF1 Antibody
Table BarTOPTable Bar
 

G-protein coupled receptor homolog UL33

 G-protein coupled receptor homolog UL33 ELISA Kit
 G-protein coupled receptor homolog UL33 Recombinant
 G-protein coupled receptor homolog UL33 Antibody
G-protein-coupled receptor (vGPCR) that constitutively activates multiple signaling pathways in a ligand independent manner. For example, promotes phospholipase C and cAMP-responsive element (CRE) pathway activation. Therefore, greatly contributes to viral pathogenesis. Inhibits US28-mediated NF-kappa-B activation ().
 UL33 ELISA Kit
 UL33 Recombinant
 UL33 Antibody
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G-protein coupled receptor homolog US27

 G-protein coupled receptor homolog US27 ELISA Kit
 G-protein coupled receptor homolog US27 Recombinant
 G-protein coupled receptor homolog US27 Antibody
Also known as G-protein coupled receptor homolog US27 (HHRF2).
Plays an important role in spread of HCMV via the extracellular route. As a G-protein-coupled receptor (vGPCR), may activate signaling pathways important for virion assembly or egress processes.
 US27 ELISA Kit
 US27 Recombinant
 US27 Antibody
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G-protein coupled receptor homolog US28

 G-protein coupled receptor homolog US28 ELISA Kit
 G-protein coupled receptor homolog US28 Recombinant
 G-protein coupled receptor homolog US28 Antibody
Also known as G-protein coupled receptor homolog US28 (HHRF3).
Receptor for a C-C type chemokine. Binds to MIP-1 alpha, RANTES, and MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. May regulate viral latency or reactivation; potential pathway for virally transformed cell proliferation.
 US28 ELISA Kit
 US28 Recombinant
 US28 Antibody
Table BarTOPTable Bar
 

G-protein coupled receptor moody

 G-protein coupled receptor moody ELISA Kit
 G-protein coupled receptor moody Recombinant
 G-protein coupled receptor moody Antibody
Isoform A and isoform B are required in glia to regulate the acute sensitivity to cocaine and to continuously maintain the proper blood-brain barrier (BBB) function. A moody-mediated signaling pathway functions in glia to regulate nervous system insulation and drug-related behaviors. Galphai and Galphao, and the regulator of G protein signaling, loco, are required in the surface glia to achieve ef
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fective insulation. The components function by regulating the cortical actin and thereby stabilizing the extended morphology of the surface glia, which in turn is necessary for the formation of septate junctions of sufficient length to achieve proper sealing of the nerve cord.
 moody ELISA Kit
 moody Recombinant
 moody Antibody
 CG4322 ELISA Kit
 CG4322 Recombinant
 CG4322 Antibody
Table BarTOPTable Bar
 

G-protein coupled receptor Mth

 G-protein coupled receptor Mth ELISA Kit
 G-protein coupled receptor Mth Recombinant
 G-protein coupled receptor Mth Antibody
Also known as G-protein coupled receptor Mth (Protein methuselah).
Involved in biological aging and stress response. Essential for adult survival ().
 mth ELISA Kit
 mth Recombinant
 mth Antibody
 GD25710 ELISA Kit
 GD25710 Recombinant
 GD25710 Antibody
Table BarTOPTable Bar
 

G-protein coupled receptor Mth2

 G-protein coupled receptor Mth2 ELISA Kit
 G-protein coupled receptor Mth2 Recombinant
 G-protein coupled receptor Mth2 Antibody
Also known as G-protein coupled receptor Mth2 (Protein methuselah-2).
Involved in biological aging and stress response. Essential for adult survival ().
 mth2 ELISA Kit
 mth2 Recombinant
 mth2 Antibody
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G-protein coupled receptor seb-2

 G-protein coupled receptor seb-2 ELISA Kit
 G-protein coupled receptor seb-2 Recombinant
 G-protein coupled receptor seb-2 Antibody
Not known. Putative receptor.
 seb-2 ELISA Kit
 seb-2 Recombinant
 seb-2 Antibody
 ZK643.3 ELISA Kit
 ZK643.3 Recombinant
 ZK643.3 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
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