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G-protein-signaling modulator

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Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.

Below are the list of possible G-protein-signaling modulator products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

G-protein-signaling modulator 1

 G-protein-signaling modulator 1 ELISA Kit
 G-protein-signaling modulator 1 Recombinant
 G-protein-signaling modulator 1 Antibody
Also known as G-protein-signaling modulator 1 (Activator of G-protein signaling 3).
GPSM1: Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation an
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d asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction. Belongs to the GPSM family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs; GEFs, misc.

Chromosomal Location of Human Ortholog: 9q34.3
 GPSM1 ELISA Kit
 GPSM1 Recombinant
 GPSM1 Antibody
 AGS3 ELISA Kit
 AGS3 Recombinant
 AGS3 Antibody
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G-protein-signaling modulator 2

 G-protein-signaling modulator 2 ELISA Kit
 G-protein-signaling modulator 2 Recombinant
 G-protein-signaling modulator 2 Antibody
Also known as G-protein-signaling modulator 2 (Mosaic protein LGN).
GPSM2: Plays an important role in spindle pole orientation. Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions. Interacts with LLGL2. Interacts with INSC/inscuteable and probably with F2RL2. Ubiquitously expressed. Belongs to the GPSM fam
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ily.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: cell cortex; cytoplasm

Molecular Function: GDP-dissociation inhibitor activity; identical protein binding; protein binding

Biological Process: G-protein coupled receptor protein signaling pathway; maintenance of centrosome localization; mitotic spindle organization and biogenesis

Disease: Chudley-mccullough Syndrome
 GPSM2 ELISA Kit
 GPSM2 Recombinant
 GPSM2 Antibody
 LGN ELISA Kit
 LGN Recombinant
 LGN Antibody
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G-protein-signaling modulator 3

 G-protein-signaling modulator 3 ELISA Kit
 G-protein-signaling modulator 3 Recombinant
 G-protein-signaling modulator 3 Antibody
GPSM3: Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins.

Protein type: G protein regulator, misc.

Cellular Component: plasma membrane

Biological Process: immune response; positive regulation of inflammatory response; positive regulation of leukocyte chemotaxis
 Gpsm3 ELISA Kit
 Gpsm3 Recombinant
 Gpsm3 Antibody
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