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G1/S-specific cyclin

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G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition and for maintenance of filamentous growth. Through binding to CDC28 controls the phosphorylation of CDC11 and SEC2 upon induction of filamentous growth.

Below are the list of possible G1/S-specific cyclin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

G1/S-specific cyclin CCN1

 G1/S-specific cyclin CCN1 ELISA Kit
 G1/S-specific cyclin CCN1 Recombinant
 G1/S-specific cyclin CCN1 Antibody
G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition and for maintenance of filamentous growth. Through binding to CDC28 controls the phosphorylation of CDC11 and SEC2 upon induction of filamentous growth.
 CCN1 ELISA Kit
 CCN1 Recombinant
 CCN1 Antibody
 CLN1 ELISA Kit
 CLN1 Recombinant
 CLN1 Antibody
 CaO19.10719 ELISA Kit
 CaO19.10719 Recombinant
 CaO19.10719 Antibody
 CaO19.3207 ELISA Kit
 CaO19.3207 Recombinant
 CaO19.3207 Antibody
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G1/S-specific cyclin CLN1

 G1/S-specific cyclin CLN1 ELISA Kit
 G1/S-specific cyclin CLN1 Recombinant
 G1/S-specific cyclin CLN1 Antibody
Essential for the control of the cell cycle at the G1/S (start) transition. Interacts with the CDC28 protein kinase to form MPF.
 CLN1 ELISA Kit
 CLN1 Recombinant
 CLN1 Antibody
 YMR199W ELISA Kit
 YMR199W Recombinant
 YMR199W Antibody
 YM9646.13 ELISA Kit
 YM9646.13 Recombinant
 YM9646.13 Antibody
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G1/S-specific cyclin CLN2

 G1/S-specific cyclin CLN2 ELISA Kit
 G1/S-specific cyclin CLN2 Recombinant
 G1/S-specific cyclin CLN2 Antibody
Essential for the control of the cell cycle at the G1/S (start) transition. Interacts with the CDC28 protein kinase to form MPF ().
 CLN2 ELISA Kit
 CLN2 Recombinant
 CLN2 Antibody
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G1/S-specific cyclin CLN3

 G1/S-specific cyclin CLN3 ELISA Kit
 G1/S-specific cyclin CLN3 Recombinant
 G1/S-specific cyclin CLN3 Antibody
Essential for the control of the cell cycle at the G1/S (start) transition. CLN3 may be an upstream activator of the G1 cyclins which directly catalyze start.
 CLN3 ELISA Kit
 CLN3 Recombinant
 CLN3 Antibody
 DAF1 ELISA Kit
 DAF1 Recombinant
 DAF1 Antibody
 WHI1 ELISA Kit
 WHI1 Recombinant
 WHI1 Antibody
 YAL040C ELISA Kit
 YAL040C Recombinant
 YAL040C Antibody
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G1/S-specific cyclin pas1

 G1/S-specific cyclin pas1 ELISA Kit
 G1/S-specific cyclin pas1 Recombinant
 G1/S-specific cyclin pas1 Antibody
Essential for the control of the cell cycle at the G1/S (start) transition. Interacts with the pef1 protein kinase. The pef1/pas1 complex activates the res2/cdc10 complex.
 pas1 ELISA Kit
 pas1 Recombinant
 pas1 Antibody
 SPAC19E9.03 ELISA Kit
 SPAC19E9.03 Recombinant
 SPAC19E9.03 Antibody
 SPAC57A10.01 ELISA Kit
 SPAC57A10.01 Recombinant
 SPAC57A10.01 Antibody
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G1/S-specific cyclin-D

 G1/S-specific cyclin-D ELISA Kit
 G1/S-specific cyclin-D Recombinant
 G1/S-specific cyclin-D Antibody
In association with cdk-4, regulates the progression through the G1 phase of the cell cycle during postembryonic development (PubMed:10518501, PubMed:11684669). Regulates proliferation of the coelomocyte lineage and intestinal cells during late embryogenesis (PubMed:15708572, PubMed:11684669). In complex with cdk-4, involved in sex determination during gonadogenesis by regulating the asymmetric di
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vision of the somatic gonadal precursor cell (SGP) (PubMed:16198291).
 cyd-1 ELISA Kit
 cyd-1 Recombinant
 cyd-1 Antibody
 Y38F1A.5 ELISA Kit
 Y38F1A.5 Recombinant
 Y38F1A.5 Antibody
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G1/S-specific cyclin-D1

 G1/S-specific cyclin-D1 ELISA Kit
 G1/S-specific cyclin-D1 Recombinant
 G1/S-specific cyclin-D1 Antibody
Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression
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through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D1/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex. Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner ().
 CCND1 ELISA Kit
 CCND1 Recombinant
 CCND1 Antibody
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G1/S-specific cyclin-D2

 G1/S-specific cyclin-D2 ELISA Kit
 G1/S-specific cyclin-D2 Recombinant
 G1/S-specific cyclin-D2 Antibody
Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression
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through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex ().
 CCND2 ELISA Kit
 CCND2 Recombinant
 CCND2 Antibody
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G1/S-specific cyclin-D3

 G1/S-specific cyclin-D3 ELISA Kit
 G1/S-specific cyclin-D3 Recombinant
 G1/S-specific cyclin-D3 Antibody
CCND3: Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the pro
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gression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/p27Kip1, required for nuclear translocation and activity of the cyclin D-CDK4 complex. Interacts with the CDK4 and CDK6 protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. Interacts with ATF5. Interacts with EIF3K. Component of the ternary complex cyclin D/CDK4/p27Kip1 required for nuclear translocation and modulation of CDK4-mediated kinase activity. Can form similar complexes with either p21Cip1 or CDKN2A. Belongs to the cyclin family. Cyclin D subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Activator; Cell cycle regulation; Nuclear receptor co-regulator

Cellular Component: cyclin-dependent protein kinase holoenzyme complex; cytoplasm; focal adhesion; nucleus; plasma membrane

Molecular Function: cyclin-dependent protein kinase activity; protein kinase binding

Biological Process: G1/S transition of mitotic cell cycle; hyaluronan biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell proliferation; positive regulation of cyclin-dependent protein kinase activity; positive regulation of protein amino acid phosphorylation; regulation of cell cycle; regulation of cell proliferation; regulation of insulin receptor signaling pathway; response to glucose stimulus; response to organic substance; response to peptide hormone stimulus; signal transduction; T cell proliferation
 Ccnd3 ELISA Kit
 Ccnd3 Recombinant
 Ccnd3 Antibody
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G1/S-specific cyclin-E

 G1/S-specific cyclin-E ELISA Kit
 G1/S-specific cyclin-E Recombinant
 G1/S-specific cyclin-E Antibody
Essential for the control of the cell cycle at the G1/S (start) transition. In association with cdk-2, regulates proliferation, quiescent state and cell fate during the development of several cell linages. In the embryo, initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase. During the development of the vulva, controls the
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onset of vulval cell terminal differentiation by controlling the duration of G1 phase. During hypoderm development at early larval stages, controls syncytial fate of seam cell daughter cells. By controlling the activity of translational repressor gld-1, regulates the pool of germline stem cells and the size of the mitotic zone by preventing entry into meiosis. In addition, repression of expression by gld-1, prevents mitosis re-entry in meiotic germline cells.
 cye-1 ELISA Kit
 cye-1 Recombinant
 cye-1 Antibody
 CBG12774 ELISA Kit
 CBG12774 Recombinant
 CBG12774 Antibody
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G1/S-specific cyclin-E1

 G1/S-specific cyclin-E1 ELISA Kit
 G1/S-specific cyclin-E1 Recombinant
 G1/S-specific cyclin-E1 Antibody
Essential for the control of the cell cycle at the G1/S (start) transition.
 cyce1 ELISA Kit
 cyce1 Recombinant
 cyce1 Antibody
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G1/S-specific cyclin-E2

 G1/S-specific cyclin-E2 ELISA Kit
 G1/S-specific cyclin-E2 Recombinant
 G1/S-specific cyclin-E2 Antibody
CCNE2: Essential for the control of the cell cycle at the late G1 and early S phase. Interacts with the CDK2 (in vivo) and CDK3 (in vitro) protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. Activated by papilloma viral oncoproteins E6 and E7 which bind to and inactivate p53 and Rb, respectively. According to PubMed
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:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor- derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon. Belongs to the cyclin family. Cyclin E subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Activator; Cell cycle regulation

Molecular Function: cyclin-dependent protein kinase regulator activity; protein kinase binding

Biological Process: DNA replication initiation; regulation of cell cycle; synapsis; telomere maintenance
 Ccne2 ELISA Kit
 Ccne2 Recombinant
 Ccne2 Antibody
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G1/S-specific cyclin-E3

 G1/S-specific cyclin-E3 ELISA Kit
 G1/S-specific cyclin-E3 Recombinant
 G1/S-specific cyclin-E3 Antibody
Essential for the control of the cell cycle at the G1/S (start) transition.
 cyce3 ELISA Kit
 cyce3 Recombinant
 cyce3 Antibody
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