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G1-specific transcriptional repressor

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Transcriptional repressor that negatively regulates G1-specific, SBF- and MBF-dependent transcription. Binds via SBF to promoters of G1-specific genes to repress transcription in early G1. During G1, phosphorylated by cyclin-CDK CLN3-CDC28 and progressively hyperphosphorylated by CDK associated with other G1-cyclins, which leads to dissociation of WHI5 from SBF, activating SBF-dependent transcription in late G1. Elimination of CDK activity at the end of mitosis by the mitotic exit network (MEN) allows WHI5 to reassociate with SBF to again repress G1/S transcription.

Below are the list of possible G1-specific transcriptional repressor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

G1-specific transcriptional repressor WHI5

 G1-specific transcriptional repressor WHI5 ELISA Kit
 G1-specific transcriptional repressor WHI5 Recombinant
 G1-specific transcriptional repressor WHI5 Antibody
Transcriptional repressor that negatively regulates G1-specific, SBF- and MBF-dependent transcription. Binds via SBF to promoters of G1-specific genes to repress transcription in early G1. During G1, phosphorylated by cyclin-CDK CLN3-CDC28 and progressively hyperphosphorylated by CDK associated with other G1-cyclins, which leads to dissociation of WHI5 from SBF, activating SBF-dependent transcription in late G1. Elimination of CDK activity at the end of mitosis by the mitotic exit network (MEN) allows WHI5 to reassociate with SBF to again repress G1/S transcription.
 WHI5 ELISA Kit
 WHI5 Recombinant
 WHI5 Antibody
 YOR083W ELISA Kit
 YOR083W Recombinant
 YOR083W Antibody
 YOR3116W ELISA Kit
 YOR3116W Recombinant
 YOR3116W Antibody
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