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Gasdermin

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May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity .

Below are the list of possible Gasdermin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Gasdermin-A

 Gasdermin-A ELISA Kit
 Gasdermin-A Recombinant
 Gasdermin-A Antibody
Also known as Gasdermin-A (Gasdermin-1).
GSDMA: Induces apoptosis. Belongs to the gasdermin family.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 17q21.1

Cellular Component: perinuclear region of cytoplasm

Biological Process: apoptosis
 GSDMA ELISA Kit
 GSDMA Recombinant
 GSDMA Antibody
 GSDM ELISA Kit
 GSDM Recombinant
 GSDM Antibody
 GSDM1 ELISA Kit
 GSDM1 Recombinant
 GSDM1 Antibody
 FKSG9 ELISA Kit
 FKSG9 Recombinant
 FKSG9 Antibody
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Gasdermin-A2

 Gasdermin-A2 ELISA Kit
 Gasdermin-A2 Recombinant
 Gasdermin-A2 Antibody
Also known as Gasdermin-A2 (Gasdermin-2).
Gsdma2: Belongs to the gasdermin family. 3 isoforms of the human protein are produced by alternative splicing.
 Gsdma2 ELISA Kit
 Gsdma2 Recombinant
 Gsdma2 Antibody
 Gsdm2 ELISA Kit
 Gsdm2 Recombinant
 Gsdm2 Antibody
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Gasdermin-A3

 Gasdermin-A3 ELISA Kit
 Gasdermin-A3 Recombinant
 Gasdermin-A3 Antibody
Also known as Gasdermin-A3 (Gasdermin-3).
Gsdma3:

Cellular Component: nucleus

Biological Process: anagen; catagen; hair cycle; hair follicle development; hair follicle morphogenesis; negative regulation of anagen; positive regulation of apoptosis; sebaceous gland cell differentiation; skin development; somatic stem cell maintenance
 Gsdma3 ELISA Kit
 Gsdma3 Recombinant
 Gsdma3 Antibody
 Gsdm3 ELISA Kit
 Gsdm3 Recombinant
 Gsdm3 Antibody
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Gasdermin-B

 Gasdermin-B ELISA Kit
 Gasdermin-B Recombinant
 Gasdermin-B Antibody
Also known as Gasdermin-B (Gasdermin-like protein).
GSDML: May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells. Belongs to the gasdermin family. 6 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q12
 GSDMB ELISA Kit
 GSDMB Recombinant
 GSDMB Antibody
 GSDML ELISA Kit
 GSDML Recombinant
 GSDML Antibody
 PP4052 ELISA Kit
 PP4052 Recombinant
 PP4052 Antibody
 PRO2521 ELISA Kit
 PRO2521 Recombinant
 PRO2521 Antibody
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Gasdermin-C

 Gasdermin-C ELISA Kit
 Gasdermin-C Recombinant
 Gasdermin-C Antibody
Also known as Gasdermin-C (Gasdermin-C1) (Melanoma-derived leucine zipper-containing extranuclear factor) (mMLZE).
MLZE: Belongs to the gasdermin family.

Cellular Component: cytoplasm; microtubule organizing center; mitochondrion
 Gsdmc ELISA Kit
 Gsdmc Recombinant
 Gsdmc Antibody
 Gsdmc1 ELISA Kit
 Gsdmc1 Recombinant
 Gsdmc1 Antibody
 Mlze ELISA Kit
 Mlze Recombinant
 Mlze Antibody
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Gasdermin-C2

 Gasdermin-C2 ELISA Kit
 Gasdermin-C2 Recombinant
 Gasdermin-C2 Antibody
GSDMC2:

Cellular Component: cytoplasm; microtubule organizing center; mitochondrion
 Gsdmc2 ELISA Kit
 Gsdmc2 Recombinant
 Gsdmc2 Antibody
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Gasdermin-C3

 Gasdermin-C3 ELISA Kit
 Gasdermin-C3 Recombinant
 Gasdermin-C3 Antibody
GSDMC3:

Cellular Component: cytoplasm; microtubule organizing center; mitochondrion
 Gsdmc3 ELISA Kit
 Gsdmc3 Recombinant
 Gsdmc3 Antibody
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Gasdermin-C4

 Gasdermin-C4 ELISA Kit
 Gasdermin-C4 Recombinant
 Gasdermin-C4 Antibody
GSDMC4:

Cellular Component: cytoplasm; microtubule organizing center; mitochondrion
 Gsdmc4 ELISA Kit
 Gsdmc4 Recombinant
 Gsdmc4 Antibody
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Gasdermin-D

 Gasdermin-D ELISA Kit
 Gasdermin-D Recombinant
 Gasdermin-D Antibody
Also known as Gasdermin-D (Gasdermin domain-containing protein 1).
FKSG10: Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: cytosol; extracellular space; nucleoplasm; plasma membrane

Molecular Function: phosphatidylinositol-4,5-
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bisphosphate binding; phosphatidylserine binding; protein binding

Biological Process: cytolysis; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; pore complex biogenesis; positive regulation of interleukin-1 beta secretion; protein homooligomerization
 GSDMD ELISA Kit
 GSDMD Recombinant
 GSDMD Antibody
 DFNA5L ELISA Kit
 DFNA5L Recombinant
 DFNA5L Antibody
 GSDMDC1 ELISA Kit
 GSDMDC1 Recombinant
 GSDMDC1 Antibody
 FKSG10 ELISA Kit
 FKSG10 Recombinant
 FKSG10 Antibody
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Proteins Root Name Listing
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