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Gastric intrinsic factor

Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the GIF-cobalamin complex is internalized via receptor-mediated endocytosis (By similarity).

Below are the list of possible Gastric intrinsic factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Gastric intrinsic factor

 Gastric intrinsic factor ELISA Kit
 Gastric intrinsic factor Recombinant
 Gastric intrinsic factor Antibody
Also known as Gastric intrinsic factor (Intrinsic factor) (IF) (INF).
GIF: Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the GIF-cobalamin complex is internalized via receptor-mediated endocytosis. Defects in GIF are the cause of hereditary intrinsic factor deficiency (IFD); also known as congenital pernicious anemia. IFD is an autosomal
recessive disorder characterized by megaloblastic anemia. Belongs to the eukaryotic cobalamin transport proteins family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: apical plasma membrane; endosome; extracellular space; microvillus

Molecular Function: cobalamin binding; vitamin binding

Biological Process: cobalamin metabolic process; cobalamin transport
 Gif ELISA Kit
 Gif Recombinant
 Gif Antibody
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