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Gem-associated protein

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The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus (By similarity).

Below are the list of possible Gem-associated protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Gem-associated protein 2

 Gem-associated protein 2 ELISA Kit
 Gem-associated protein 2 Recombinant
 Gem-associated protein 2 Antibody
Also known as Gem-associated protein 2 (Gemin-2) (Component of gems 2) (Survival of motor neuron protein-interacting protein 1) (SMN-interacting protein 1).
SIP1: The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. Belongs to the gemin-2 family. 4 isoforms of the human protein are produced by alternative s
>>>
plicing.

Protein type: RNA splicing

Cellular Component: cytoplasm; cytosol; intracellular; nucleolus; nucleus; SMN complex

Biological Process: spliceosomal snRNP biogenesis
 Gemin2 ELISA Kit
 Gemin2 Recombinant
 Gemin2 Antibody
 Sip1 ELISA Kit
 Sip1 Recombinant
 Sip1 Antibody
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Gem-associated protein 4

 Gem-associated protein 4 ELISA Kit
 Gem-associated protein 4 Recombinant
 Gem-associated protein 4 Antibody
Also known as Gem-associated protein 4 (Gemin-4) (Component of gems 4) (p97).
GEMIN4: The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.

Protein type: Nucleolus; RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: 17p13

Cellular Component: cytoplasm; cytosol; membrane; n
>>>
ucleoplasm; nucleus; small nuclear ribonucleoprotein complex; SMN complex

Molecular Function: protein binding

Biological Process: nuclear import; spliceosomal snRNP biogenesis
 GEMIN4 ELISA Kit
 GEMIN4 Recombinant
 GEMIN4 Antibody
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Gem-associated protein 5

 Gem-associated protein 5 ELISA Kit
 Gem-associated protein 5 Recombinant
 Gem-associated protein 5 Antibody
Also known as Gem-associated protein 5 (Gemin5).
GEMIN5: the snRNA-binding protein of the SMN complex. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. Found both in the nucleoplasm and in nuclear bodies called gems (Gemini of Cajal bodies) that are often in proximity to Cajal (coiled) bodies. Also foun
>>>
d in the cytoplasm.

Protein type: Nuclear receptor co-regulator; RNA processing; RNA splicing; RNA-binding

Cellular Component: cytoplasm; cytosol; membrane; nuclear body; nucleoplasm; nucleus; SMN complex

Molecular Function: snRNA binding

Biological Process: spliceosomal snRNP biogenesis
 Gemin5 ELISA Kit
 Gemin5 Recombinant
 Gemin5 Antibody
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Gem-associated protein 6

 Gem-associated protein 6 ELISA Kit
 Gem-associated protein 6 Recombinant
 Gem-associated protein 6 Antibody
Also known as Gem-associated protein 6 (Gemin-6).
GEMIN6: The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.

Protein type: RNA splicing

Cellular Component: cytoplasm; cytosol; nuclear body; nucleoplasm; SMN complex

Molecular Function: protein binding

Biological Process: spliceo
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somal snRNP biogenesis
 Gemin6 ELISA Kit
 Gemin6 Recombinant
 Gemin6 Antibody
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Gem-associated protein 7

 Gem-associated protein 7 ELISA Kit
 Gem-associated protein 7 Recombinant
 Gem-associated protein 7 Antibody
Also known as Gem-associated protein 7 (Gemin-7).
GEMIN7: The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. Belongs to the gemin-7 family.

Protein type: RNA splicing

Cellular Component: cytoplasm; cytosol; nuclear body; nucleoplasm; nucleus; SMN complex

Molecular Function: protein bi
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nding

Biological Process: spliceosomal snRNP biogenesis
 Gemin7 ELISA Kit
 Gemin7 Recombinant
 Gemin7 Antibody
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Gem-associated protein 7 homolog

 Gem-associated protein 7 homolog ELISA Kit
 Gem-associated protein 7 homolog Recombinant
 Gem-associated protein 7 homolog Antibody
 new17 ELISA Kit
 new17 Recombinant
 new17 Antibody
 SPBC32F12.16 ELISA Kit
 SPBC32F12.16 Recombinant
 SPBC32F12.16 Antibody
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Gem-associated protein 8

 Gem-associated protein 8 ELISA Kit
 Gem-associated protein 8 Recombinant
 Gem-associated protein 8 Antibody
Also known as Gem-associated protein 8 (Gemin-8).
The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a h
>>>
eptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus ().
 GEMIN8 ELISA Kit
 GEMIN8 Recombinant
 GEMIN8 Antibody
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Proteins Root Name Listing
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