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GLH-binding kinase

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Mitogen-activated protein kinase which is an essential component of the JNK pathway composed of mlk-1, mek-1 and kgb-1 .

Below are the list of possible GLH-binding kinase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

GLH-binding kinase 1

 GLH-binding kinase 1 ELISA Kit
 GLH-binding kinase 1 Recombinant
 GLH-binding kinase 1 Antibody
Mitogen-activated protein kinase which is an essential component of the JNK pathway composed of mlk-1, mek-1 and kgb-1 (PubMed:15116070, PubMed:22554143, PubMed:23352664). Phosphorylates the transcription factor fos-1 which prevents fos-1 dimerization and promoter binding and results in activation of target genes including F53A9.2/kreg-1 and lys-3/kreg-2 (PubMed:23437011). Phosphorylates jun-1 and
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activates the AP-1 transcription factor which is a heterodimer of jun-1 and fos-1 (PubMed:23352664). Phosphorylates glh-1 in vitro which may play a role in controlling glh-1 protein levels in the germline by targeting it for degradation by the proteasome (PubMed:17699606). Required for oogenesis and probably also for spermatogenesis (PubMed:12435362). Involved in the response to environmental stress such as heavy metals, infection and protein folding stress in an age-dependent manner (PubMed:15116070, PubMed:22554143). In larvae, has a protective role which becomes detrimental in adults (PubMed:22554143). May control susceptibility to infection, heavy metal stress and premature lethality by regulating daf-16 cellular localization (PubMed:22554143). Involved in the transcriptional response to bacterial pore-forming toxins and to fasting (PubMed:15256590, PubMed:21408619, PubMed:23352664). Required for fasting-induced longevity (PubMed:23352664). Involved in axon regeneration after injury downstream of tyrosine receptor svh-2 (PubMed:21670305, PubMed:22388962).
 kgb-1 ELISA Kit
 kgb-1 Recombinant
 kgb-1 Antibody
 T07A9.3 ELISA Kit
 T07A9.3 Recombinant
 T07A9.3 Antibody
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