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Glomulin

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Essential for normal development of the vasculature. May represent a naturally occurring ligand of the immunophilins FKBP59 and FKBP12. May function as an membrane anchoring protein. May stimulate the p70S6K pathway. May inhibit cell proliferation and increase IL2 production (By similarity).

Below are the list of possible Glomulin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Glomulin

 Glomulin ELISA Kit
 Glomulin Recombinant
 Glomulin Antibody
Also known as Glomulin (FK506-binding protein-associated protein) (FAP) (FKBP-associated protein).
GLMN: Essential for normal development of the vasculature. May represent a naturally occurring ligand of the immunophilins FKBP59 and FKBP12. May function as an membrane anchoring protein. Isoform 1 may stimulate the p70S6K pathway. Isoform 2 may inhibit cell proliferation and increase IL2 product
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ion. Defects in GLMN are the cause of glomuvenous malformations (GVMs). GVMs are characterized by the presence of smooth-muscle-like glomus cells in the media surrounding distended vascular lumens. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine

Cellular Component: Cul2-RING ubiquitin ligase complex; cullin-RING ubiquitin ligase complex; cytoplasm

Molecular Function: hepatocyte growth factor receptor binding; protein binding; receptor binding; ubiquitin protein ligase binding; ubiquitin-protein ligase inhibitor activity

Biological Process: cell surface receptor linked signal transduction; muscle cell differentiation; negative regulation of cell proliferation; negative regulation of T cell proliferation; neural tube closure; positive regulation of cytokine secretion; positive regulation of interleukin-2 biosynthetic process; positive regulation of phosphorylation; regulation of gene expression, epigenetic; regulation of proteasomal ubiquitin-dependent protein catabolic process; vasculogenesis
 Glmn ELISA Kit
 Glmn Recombinant
 Glmn Antibody
 Fap48 ELISA Kit
 Fap48 Recombinant
 Fap48 Antibody
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