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Glutamate receptor ionotropic

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Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.

Below are the list of possible Glutamate receptor ionotropic products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Glutamate receptor ionotropic, delta-1

 Glutamate receptor ionotropic, delta-1 ELISA Kit
 Glutamate receptor ionotropic, delta-1 Recombinant
 Glutamate receptor ionotropic, delta-1 Antibody
Also known as Glutamate receptor ionotropic, delta-1 (GluD1) (GluR delta-1 subunit).
GluR-delta1: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Belongs to the glutamate-gated ion channel (TC 1.A.
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10.1) family. GRID1 subfamily.

Protein type: Channel, calcium; Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass; Receptor, misc.

Cellular Component: postsynaptic membrane

Biological Process: social behavior
 Grid1 ELISA Kit
 Grid1 Recombinant
 Grid1 Antibody
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Glutamate receptor ionotropic, delta-2

 Glutamate receptor ionotropic, delta-2 ELISA Kit
 Glutamate receptor ionotropic, delta-2 Recombinant
 Glutamate receptor ionotropic, delta-2 Antibody
Also known as Glutamate receptor ionotropic, delta-2 (GluD2) (GluR delta-2 subunit).
GluR-delta2: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Belongs to the glutamate-gated ion channel (TC 1.A.
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10.1) family. GRID2 subfamily.

Protein type: Channel, calcium; Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: dendritic spine; ionotropic glutamate receptor complex; membrane; plasma membrane; postsynaptic density; postsynaptic membrane; synapse

Molecular Function: PDZ domain binding; protein binding

Biological Process: cerebellar granule cell differentiation; heterophilic cell adhesion; prepulse inhibition; regulation of excitatory postsynaptic membrane potential; regulation of neuron apoptosis; synaptic transmission, glutamatergic
 Grid2 ELISA Kit
 Grid2 Recombinant
 Grid2 Antibody
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Glutamate receptor ionotropic, kainate 1

 Glutamate receptor ionotropic, kainate 1 ELISA Kit
 Glutamate receptor ionotropic, kainate 1 Recombinant
 Glutamate receptor ionotropic, kainate 1 Antibody
Also known as Glutamate receptor ionotropic, kainate 1 (GluK1) (Excitatory amino acid receptor 3) (EAA3) (Glutamate receptor 5) (GluR-5) (GluR5).
GluR5: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of t
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he cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK1 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 21q22.11

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: kainate selective glutamate receptor activity; ligand-gated ion channel activity

Biological Process: central nervous system development; glutamate signaling pathway; nervous system development; regulation of synaptic transmission, glutamatergic; synaptic transmission; transport
 GRIK1 ELISA Kit
 GRIK1 Recombinant
 GRIK1 Antibody
 GLUR5 ELISA Kit
 GLUR5 Recombinant
 GLUR5 Antibody
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Glutamate receptor ionotropic, kainate 2

 Glutamate receptor ionotropic, kainate 2 ELISA Kit
 Glutamate receptor ionotropic, kainate 2 Recombinant
 Glutamate receptor ionotropic, kainate 2 Antibody
Also known as Glutamate receptor ionotropic, kainate 2 (GluK2) (Excitatory amino acid receptor 4) (EAA4) (Glutamate receptor 6) (GluR-6) (GluR6).
GluR6: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of t
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he cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2. Defects in GRIK2 are the cause of mental retardation autosomal recessive type 6 (MRT6). It is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. In contrast to syndromic or specific mental retardation which also present with associated physical, neurological and/or psychiatric manifestations, intellectual deficiency is the only primary symptom of non-syndromic mental retardation. MRT6 patients display mild to severe mental retardation and psychomotor development delay in early childhood. Patients do not have neurologic problems, congenital malformations, or facial dysmorphism. Body height, weight, and head circumference are normal. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK2 subfamily. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, calcium; Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6q16.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: kainate selective glutamate receptor activity; ligand-gated ion channel activity

Biological Process: glutamate signaling pathway; positive regulation of synaptic transmission; regulation of short-term neuronal synaptic plasticity; regulation of synaptic transmission; synaptic transmission

Disease: Mental Retardation, Autosomal Recessive 6
 GRIK2 ELISA Kit
 GRIK2 Recombinant
 GRIK2 Antibody
 GLUR6 ELISA Kit
 GLUR6 Recombinant
 GLUR6 Antibody
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Glutamate receptor ionotropic, kainate 3

 Glutamate receptor ionotropic, kainate 3 ELISA Kit
 Glutamate receptor ionotropic, kainate 3 Recombinant
 Glutamate receptor ionotropic, kainate 3 Antibody
Also known as Glutamate receptor ionotropic, kainate 3 (GluK3) (Excitatory amino acid receptor 5) (EAA5) (Glutamate receptor 7) (GluR-7) (GluR7).
GluR7: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central
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nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK3 subfamily.

Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass; Receptor, misc.

Chromosomal Location of Human Ortholog: 1p34.3

Cellular Component: axon; dendrite; dendrite cytoplasm; integral to plasma membrane; perikaryon; plasma membrane; terminal button

Molecular Function: adenylate cyclase inhibiting metabotropic glutamate receptor activity; G-protein-coupled receptor binding; glutamate receptor activity; ionotropic glutamate receptor activity; kainate selective glutamate receptor activity; ligand-gated ion channel activity

Biological Process: glutamate signaling pathway; metabotropic glutamate receptor signaling pathway; negative regulation of synaptic transmission, glutamatergic; regulation of membrane potential
 GRIK3 ELISA Kit
 GRIK3 Recombinant
 GRIK3 Antibody
 GLUR7 ELISA Kit
 GLUR7 Recombinant
 GLUR7 Antibody
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Glutamate receptor ionotropic, kainate 4

 Glutamate receptor ionotropic, kainate 4 ELISA Kit
 Glutamate receptor ionotropic, kainate 4 Recombinant
 Glutamate receptor ionotropic, kainate 4 Antibody
Also known as Glutamate receptor ionotropic, kainate 4 (GluK4).
GluR KA1: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK4 subf
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amily.

Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: axon; dendrite; kainate selective glutamate receptor complex; membrane; nucleus; perikaryon; postsynaptic membrane; presynaptic membrane; synapse; terminal button

Molecular Function: protein binding
 Grik4 ELISA Kit
 Grik4 Recombinant
 Grik4 Antibody
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Glutamate receptor ionotropic, kainate 5

 Glutamate receptor ionotropic, kainate 5 ELISA Kit
 Glutamate receptor ionotropic, kainate 5 Recombinant
 Glutamate receptor ionotropic, kainate 5 Antibody
Also known as Glutamate receptor ionotropic, kainate 5 (GluK5) (Excitatory amino acid receptor 2) (EAA2) (Glutamate receptor KA-2) (KA2).
GluR KA2: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. T
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his receptor binds kainate > quisqualate > domoate > L- glutamate >> AMPA >> NMDA = 1S,3R-ACPD. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: plasma membrane

Molecular Function: kainate selective glutamate receptor activity; ligand-gated ion channel activity
 GRIK5 ELISA Kit
 GRIK5 Recombinant
 GRIK5 Antibody
 GRIK2 ELISA Kit
 GRIK2 Recombinant
 GRIK2 Antibody
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Glutamate receptor ionotropic, NMDA 1

 Glutamate receptor ionotropic, NMDA 1 ELISA Kit
 Glutamate receptor ionotropic, NMDA 1 Recombinant
 Glutamate receptor ionotropic, NMDA 1 Antibody
Also known as Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor 1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1).
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synapt
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ogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors ().
 GRIN1 ELISA Kit
 GRIN1 Recombinant
 GRIN1 Antibody
 NMDAR1 ELISA Kit
 NMDAR1 Recombinant
 NMDAR1 Antibody
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Glutamate receptor ionotropic, NMDA 2A

 Glutamate receptor ionotropic, NMDA 2A ELISA Kit
 Glutamate receptor ionotropic, NMDA 2A Recombinant
 Glutamate receptor ionotropic, NMDA 2A Antibody
Also known as Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A).
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits ().
 GRIN2A ELISA Kit
 GRIN2A Recombinant
 GRIN2A Antibody
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Glutamate receptor ionotropic, NMDA 2B

 Glutamate receptor ionotropic, NMDA 2B ELISA Kit
 Glutamate receptor ionotropic, NMDA 2B Recombinant
 Glutamate receptor ionotropic, NMDA 2B Antibody
Also known as Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B).
NMDAR2B: an NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, exci
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totoxicity, memory acquisition and learning. Mediates neuronal functions in glutamate neurotransmission. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death.

Protein type: Channel, calcium; Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: cell surface; dendritic spine; membrane; N-methyl-D-aspartate selective glutamate receptor complex; neuron projection; postsynaptic density; postsynaptic membrane; presynaptic membrane; synapse; synaptic vesicle; terminal button; Z disc

Molecular Function: beta-catenin binding; calcium channel activity; cation channel activity; cell adhesion molecule binding; D2 dopamine receptor binding; drug binding; extracellular-glutamate-gated ion channel activity; glycine binding; interleukin-1 receptor binding; ionotropic glutamate receptor activity; ionotropic glutamate receptor binding; N-methyl-D-aspartate selective glutamate receptor activity; neurotransmitter binding; protein binding; protein heterodimerization activity; receptor binding; zinc ion binding

Biological Process: associative learning; behavioral fear response; behavioral response to pain; calcium ion transport; cation transport; cellular response to magnesium starvation; cerebral cortex development; detection of mechanical stimulus involved in sensory perception of pain; fear response; hippocampus development; in utero embryonic development; ionotropic glutamate receptor signaling pathway; learning; learning and/or memory; long-term memory; memory; multicellular organismal response to stress; positive regulation of glutamate secretion; positive regulation of synaptic transmission; receptor clustering; regulation of action potential; regulation of excitatory postsynaptic membrane potential; regulation of long-term neuronal synaptic plasticity; regulation of MAPKKK cascade; regulation of postsynaptic membrane potential; regulation of synaptic plasticity; response to amine stimulus; response to amphetamine; response to calcium ion; response to carbohydrate stimulus; response to cocaine; response to cytokine stimulus; response to electrical stimulus; response to ethanol; response to magnesium ion; response to manganese ion; response to mechanical stimulus; response to methylmercury; response to organic cyclic substance; response to other organism; response to toxin; rhythmic process; sensory organ development; startle response; suckling behavior; synaptic transmission
 Grin2b ELISA Kit
 Grin2b Recombinant
 Grin2b Antibody
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Glutamate receptor ionotropic, NMDA 2C

 Glutamate receptor ionotropic, NMDA 2C ELISA Kit
 Glutamate receptor ionotropic, NMDA 2C Recombinant
 Glutamate receptor ionotropic, NMDA 2C Antibody
Also known as Glutamate receptor ionotropic, NMDA 2C (GluN2C) (Glutamate [NMDA] receptor subunit epsilon-3) (N-methyl D-aspartate receptor subtype 2C) (NMDAR2C) (NR2C).
NMDAR2C: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
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NR2C/GRIN2C subfamily.

Protein type: Channel, calcium; Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: N-methyl-D-aspartate selective glutamate receptor complex; postsynaptic density

Molecular Function: cation channel activity; ionotropic glutamate receptor activity; N-methyl-D-aspartate selective glutamate receptor activity; PDZ domain binding; protein binding; protein N-terminus binding

Biological Process: directional locomotion; negative regulation of protein catabolic process; neuromuscular process controlling balance; protein localization; regulation of excitatory postsynaptic membrane potential; regulation of membrane potential; response to wounding; startle response
 Grin2c ELISA Kit
 Grin2c Recombinant
 Grin2c Antibody
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Glutamate receptor ionotropic, NMDA 2D

 Glutamate receptor ionotropic, NMDA 2D ELISA Kit
 Glutamate receptor ionotropic, NMDA 2D Recombinant
 Glutamate receptor ionotropic, NMDA 2D Antibody
Also known as Glutamate receptor ionotropic, NMDA 2D (GluN2D) (EB11) (Glutamate [NMDA] receptor subunit epsilon-4) (N-methyl D-aspartate receptor subtype 2D) (NMDAR2D) (NR2D).
NMDAR2D: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2D/GRIN2D subfamily.

Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19q13.33

Cellul
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ar Component: N-methyl-D-aspartate selective glutamate receptor complex; plasma membrane

Molecular Function: ionotropic glutamate receptor activity; N-methyl-D-aspartate selective glutamate receptor activity; protein binding; Ras guanyl-nucleotide exchange factor activity

Biological Process: MAPKKK cascade; synaptic transmission

Disease: Epileptic Encephalopathy, Early Infantile, 46
 GRIN2D ELISA Kit
 GRIN2D Recombinant
 GRIN2D Antibody
 GluN2D ELISA Kit
 GluN2D Recombinant
 GluN2D Antibody
 NMDAR2D ELISA Kit
 NMDAR2D Recombinant
 NMDAR2D Antibody
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Glutamate receptor ionotropic, NMDA 3A

 Glutamate receptor ionotropic, NMDA 3A ELISA Kit
 Glutamate receptor ionotropic, NMDA 3A Recombinant
 Glutamate receptor ionotropic, NMDA 3A Antibody
Also known as Glutamate receptor ionotropic, NMDA 3A (GluN3A) (Glutamate receptor chi-1) (N-methyl-D-aspartate receptor) (N-methyl-D-aspartate receptor subtype 3A) (NMDAR3A) (NR3A) (NMDAR-L) (NMDAR-L1).
NMDAR3A: NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by g
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lycine. May play a role in the development of dendritic spines. May play a role in PPP2CB-NMDAR mediated signaling mechanism. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3A/GRIN3A subfamily.

Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: cell soma; membrane; N-methyl-D-aspartate selective glutamate receptor complex; neuron projection; postsynaptic membrane; synapse

Molecular Function: calcium channel activity; glycine binding; identical protein binding; ionotropic glutamate receptor activity; N-methyl-D-aspartate selective glutamate receptor activity; neurotransmitter binding; protein binding; protein phosphatase 2A binding

Biological Process: calcium ion transport; dendrite development; ionotropic glutamate receptor signaling pathway; prepulse inhibition; response to ethanol; rhythmic process
 Grin3a ELISA Kit
 Grin3a Recombinant
 Grin3a Antibody
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Glutamate receptor ionotropic, NMDA 3B

 Glutamate receptor ionotropic, NMDA 3B ELISA Kit
 Glutamate receptor ionotropic, NMDA 3B Recombinant
 Glutamate receptor ionotropic, NMDA 3B Antibody
Also known as Glutamate receptor ionotropic, NMDA 3B (GluN3B) (N-methyl-D-aspartate receptor subtype 3B) (NMDAR3B) (NR3B).
NMDAR3B: NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3B/GR
>>>
IN3B subfamily.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cell soma; N-methyl-D-aspartate selective glutamate receptor complex

Molecular Function: calcium channel activity; cation channel activity; glycine binding; N-methyl-D-aspartate selective glutamate receptor activity; neurotransmitter binding; neurotransmitter receptor activity

Biological Process: ionotropic glutamate receptor signaling pathway; protein insertion into membrane; regulation of calcium ion transport
 GRIN3B ELISA Kit
 GRIN3B Recombinant
 GRIN3B Antibody
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