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Glycine--tRNA ligase

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Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.

Below are the list of possible Glycine--tRNA ligase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Glycine--tRNA ligase

 Glycine--tRNA ligase ELISA Kit
 Glycine--tRNA ligase Recombinant
 Glycine--tRNA ligase Antibody
Also known as Glycine--tRNA ligase (Diadenosine tetraphosphate synthetase) (AP-4-A synthetase) (Glycyl-tRNA synthetase) (GlyRS).
GARS: Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Defects in GARS are the cause of Charcot-M
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arie-Tooth disease type 2D (CMT2D). CMT2D is a form of Charcot- Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathy or CMT1, and primary peripheral axonal neuropathy or CMT2. Neuropathies of the CMT2 group are characterized by signs of axonal regeneration in the absence of obvious myelin alterations, normal or slightly reduced nerve conduction velocities, and progressive distal muscle weakness and atrophy. CMT2D is characterized by a more severe phenotype in the upper extremities (severe weakness and atrophy, absence of tendon reflexes) than in the lower limbs. CMT2D inheritance is autosomal dominant. Defects in GARS are a cause of distal hereditary motor neuronopathy type 5A (HMN5A); also known as distal hereditary motor neuropathy type V (DSMAV). A disorder characterized by distal muscular atrophy mainly affecting the upper extremities, in contrast to other distal motor neuronopathies. These constitute a heterogeneous group of neuromuscular diseases caused by selective degeneration of motor neurons in the anterior horn of the spinal cord, without sensory deficit in the posterior horn. The overall clinical picture consists of a classical distal muscular atrophy syndrome in the legs without clinical sensory loss. The disease starts with weakness and wasting of distal muscles of the anterior tibial and peroneal compartments of the legs. Later on, weakness and atrophy may expand to the proximal muscles of the lower limbs and/or to the distal upper limbs. Belongs to the class-II aminoacyl-tRNA synthetase family.

Protein type: EC 6.1.1.14; Ligase; Mitochondrial; Translation

Chromosomal Location of Human Ortholog: 7p15

Cellular Component: axon; cytoplasm; cytosol; mitochondrial matrix; nucleoplasm

Molecular Function: bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity; glycine-tRNA ligase activity; protein dimerization activity

Biological Process: diadenosine tetraphosphate biosynthetic process; glycyl-tRNA aminoacylation; tRNA aminoacylation for protein translation

Disease: Charcot-marie-tooth Disease, Axonal, Type 2d; Neuronopathy, Distal Hereditary Motor, Type Va
 GARS ELISA Kit
 GARS Recombinant
 GARS Antibody
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Glycine--tRNA ligase 1

 Glycine--tRNA ligase 1 ELISA Kit
 Glycine--tRNA ligase 1 Recombinant
 Glycine--tRNA ligase 1 Antibody
Also known as Glycine--tRNA ligase 1, mitochondrial (Diadenosine tetraphosphate synthetase) (AP-4-A synthetase) (Glycyl-tRNA synthetase 1) (GlyRS 1) (GlyRS1).
Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs ().
 GRS1 ELISA Kit
 GRS1 Recombinant
 GRS1 Antibody
 YBR121C ELISA Kit
 YBR121C Recombinant
 YBR121C Antibody
 YBR0917 ELISA Kit
 YBR0917 Recombinant
 YBR0917 Antibody
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Glycine--tRNA ligase 2

 Glycine--tRNA ligase 2 ELISA Kit
 Glycine--tRNA ligase 2 Recombinant
 Glycine--tRNA ligase 2 Antibody
Also known as Glycine--tRNA ligase 2 (Diadenosine tetraphosphate synthetase) (AP-4-A synthetase) (Glycyl-tRNA synthetase 2) (GlyRS 2) (GlyRS2).
Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs ().
 GRS2 ELISA Kit
 GRS2 Recombinant
 GRS2 Antibody
 YPR081C ELISA Kit
 YPR081C Recombinant
 YPR081C Antibody
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Glycine--tRNA ligase alpha subunit

 Glycine--tRNA ligase alpha subunit ELISA Kit
 Glycine--tRNA ligase alpha subunit Recombinant
 Glycine--tRNA ligase alpha subunit Antibody
Also known as Glycine--tRNA ligase alpha subunit (Glycyl-tRNA synthetase alpha subunit) (GlyRS).
 glyQ ELISA Kit
 glyQ Recombinant
 glyQ Antibody
 AM1_3163 ELISA Kit
 AM1_3163 Recombinant
 AM1_3163 Antibody
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Glycine--tRNA ligase beta subunit

 Glycine--tRNA ligase beta subunit ELISA Kit
 Glycine--tRNA ligase beta subunit Recombinant
 Glycine--tRNA ligase beta subunit Antibody
Also known as Glycine--tRNA ligase beta subunit (Glycyl-tRNA synthetase beta subunit) (GlyRS).
 glyS ELISA Kit
 glyS Recombinant
 glyS Antibody
 ABSDF0371 ELISA Kit
 ABSDF0371 Recombinant
 ABSDF0371 Antibody
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Glycine--tRNA ligase1

 Glycine--tRNA ligase1 ELISA Kit
 Glycine--tRNA ligase1 Recombinant
 Glycine--tRNA ligase1 Antibody
Also known as Glycine--tRNA ligase, mitochondrial 1 (Diadenosine tetraphosphate synthetase) (AP-4-A synthetase) (Glycyl-tRNA synthetase 1) (GlyRS-1).
Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.
 At1g29880 ELISA Kit
 At1g29880 Recombinant
 At1g29880 Antibody
 F1N18.8 ELISA Kit
 F1N18.8 Recombinant
 F1N18.8 Antibody
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Proteins Root Name Listing
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