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Growth arrest and DNA damage-inducible protein

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Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity).

Below are the list of possible Growth arrest and DNA damage-inducible protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Growth arrest and DNA damage-inducible protein GADD45 alpha

 Growth arrest and DNA damage-inducible protein GADD45 alpha ELISA Kit
 Growth arrest and DNA damage-inducible protein GADD45 alpha Recombinant
 Growth arrest and DNA damage-inducible protein GADD45 alpha Antibody
Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity ().
 GADD45A ELISA Kit
 GADD45A Recombinant
 GADD45A Antibody
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Growth arrest and DNA damage-inducible protein GADD45 beta

 Growth arrest and DNA damage-inducible protein GADD45 beta ELISA Kit
 Growth arrest and DNA damage-inducible protein GADD45 beta Recombinant
 Growth arrest and DNA damage-inducible protein GADD45 beta Antibody
GADD45B: Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK. Belongs to the GADD45 family.

Protein type: Apoptosis; Cell development/differentiation

Cellular Component: cytoplasm; nucleus

Biological Process: activation of MAPKKK activity; regulation of cell cycle
 GADD45B ELISA Kit
 GADD45B Recombinant
 GADD45B Antibody
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Growth arrest and DNA damage-inducible protein GADD45 gamma

 Growth arrest and DNA damage-inducible protein GADD45 gamma ELISA Kit
 Growth arrest and DNA damage-inducible protein GADD45 gamma Recombinant
 Growth arrest and DNA damage-inducible protein GADD45 gamma Antibody
GADD45G: I

Protein type: Apoptosis; DNA repair, damage; Nuclear receptor co-regulator

Cellular Component: cytoplasm; nucleus

Biological Process: activation of MAPKK activity; activation of MAPKKK activity; negative regulation of protein kinase activity; positive regulation of apoptosis; positive regulation of JNK cascade; regulation of cell cycle
 Gadd45g ELISA Kit
 Gadd45g Recombinant
 Gadd45g Antibody
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Growth arrest and DNA damage-inducible proteins-interacting protein 1

 Growth arrest and DNA damage-inducible proteins-interacting protein 1 ELISA Kit
 Growth arrest and DNA damage-inducible proteins-interacting protein 1 Recombinant
 Growth arrest and DNA damage-inducible proteins-interacting protein 1 Antibody
Also known as Growth arrest and DNA damage-inducible proteins-interacting protein 1 (39S ribosomal protein L59, mitochondrial) (MRP-L59).
GADD45GIP1: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan
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nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. Interacts with GADD45A, GADD45B and GADD45G. Interacts with NR4A1 via the NR4A1 AB domain. Interacts with the human papilloma virus type 16 (HPV 16) minor capsid protein L2. Down-regulated by p53/TP53 in apoptotic cells. Widely expressed. Highly expressed in the thyroid gland, heart, lymph nodes, trachea and adrenal tissues. Expressed at lower level in liver skeletal muscle, kidney, pancreas, testis, ovary and stomach. Barely detectable in adrenal adenoma and papillary thyroid cancer.

Protein type: Cell cycle regulation; Nuclear receptor co-regulator

Cellular Component: mitochondrial ribosome; mitochondrion

Biological Process: positive regulation of cell proliferation
 Gadd45gip1 ELISA Kit
 Gadd45gip1 Recombinant
 Gadd45gip1 Antibody
 Mrpl59 ELISA Kit
 Mrpl59 Recombinant
 Mrpl59 Antibody
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