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Guanine-nucleotide exchange factor

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Guanine nucleotide exchange factor for ARF3 required for localization of ARF3 to the bud neck and tip and involved in actin patch polarization.

Below are the list of possible Guanine-nucleotide exchange factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Guanine nucleotide exchange factor BopE

 Guanine nucleotide exchange factor BopE ELISA Kit
 Guanine nucleotide exchange factor BopE Recombinant
 Guanine nucleotide exchange factor BopE Antibody
Also known as Guanine nucleotide exchange factor BopE (Effector protein BopE).
Activator for both CDC42 and RAC1 by directly interacting with these Rho GTPases and acting as a guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, thus promoting bacterial entry into non-phagocytic cells ().
 bopE ELISA Kit
 bopE Recombinant
 bopE Antibody
 BMA10229_2078 ELISA Kit
 BMA10229_2078 Recombinant
 BMA10229_2078 Antibody
Table BarTOPTable Bar
 

Guanine nucleotide exchange factor DBS

 Guanine nucleotide exchange factor DBS ELISA Kit
 Guanine nucleotide exchange factor DBS Recombinant
 Guanine nucleotide exchange factor DBS Antibody
Also known as Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein).
ARHGEF14: Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of
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RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus. Isoform 5 activates CDC42. Belongs to the MCF2 family. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs; GEFs, Rac/Rho; Oncoprotein

Cellular Component: cytoplasm; extracellular space; extrinsic to membrane; lamellipodium; membrane

Molecular Function: phosphatidylinositol binding; phosphoinositide binding; protein binding; Rho guanyl-nucleotide exchange factor activity

Biological Process: positive regulation of Rho protein signal transduction; positive regulation of transcription from RNA polymerase II promoter; Rho protein signal transduction
 Mcf2l ELISA Kit
 Mcf2l Recombinant
 Mcf2l Antibody
 Dbs ELISA Kit
 Dbs Recombinant
 Dbs Antibody
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Guanine nucleotide exchange factor for Rab-3A

 Guanine nucleotide exchange factor for Rab-3A ELISA Kit
 Guanine nucleotide exchange factor for Rab-3A Recombinant
 Guanine nucleotide exchange factor for Rab-3A Antibody
Also known as Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1).
RAB3IL1: Guanine nucleotide exchange factor (GEF) for Rab3A, a GTPase that regulates synaptic vesicle exocytosis. Belongs to the SEC2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs; GEFs, Rab<
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Molecular Function: kinase binding; protein binding; Rab guanyl-nucleotide exchange factor activity
 Rab3il1 ELISA Kit
 Rab3il1 Recombinant
 Rab3il1 Antibody
 Grab ELISA Kit
 Grab Recombinant
 Grab Antibody
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Guanine nucleotide exchange factor LTE1

 Guanine nucleotide exchange factor LTE1 ELISA Kit
 Guanine nucleotide exchange factor LTE1 Recombinant
 Guanine nucleotide exchange factor LTE1 Antibody
GDP-GTP exchange factor component of the mitotic exit network (MEN). Fine-tunes the timing of the mitotic exit and couples this event with cytokinesis. May also be involved in proprotein-processing in the secretory pathway ().
 LTE1 ELISA Kit
 LTE1 Recombinant
 LTE1 Antibody
 KLLA0A04059g ELISA Kit
 KLLA0A04059g Recombinant
 KLLA0A04059g Antibody
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Guanine nucleotide exchange factor MSS4

 Guanine nucleotide exchange factor MSS4 ELISA Kit
 Guanine nucleotide exchange factor MSS4 Recombinant
 Guanine nucleotide exchange factor MSS4 Antibody
Also known as Guanine nucleotide exchange factor MSS4 (Rab-interacting factor).
RasGRF3: Guanine-nucleotide-releasing protein that acts on members of the SCE4/YPT1/RAB subfamily. Stimulates GDP release from both YPT1 and RAB3A, but is less active on these proteins than on the SEC4 protein. Might play a general role in vesicular transport. Belongs to the DSS4/MSS4 family.

Protein type: GA
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Ps; GAPs, Rab

Cellular Component: cytosol; membrane

Molecular Function: guanyl-nucleotide exchange factor activity; zinc ion binding

Biological Process: post-Golgi vesicle-mediated transport
 Rabif ELISA Kit
 Rabif Recombinant
 Rabif Antibody
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Guanine nucleotide exchange factor MSS4 homolog

 Guanine nucleotide exchange factor MSS4 homolog ELISA Kit
 Guanine nucleotide exchange factor MSS4 homolog Recombinant
 Guanine nucleotide exchange factor MSS4 homolog Antibody
Guanine-nucleotide-releasing protein that acts on members of the sec4/ypt1/rab subfamily.
 CG7787 ELISA Kit
 CG7787 Recombinant
 CG7787 Antibody
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Guanine nucleotide exchange factor rei-1

 Guanine nucleotide exchange factor rei-1 ELISA Kit
 Guanine nucleotide exchange factor rei-1 Recombinant
 Guanine nucleotide exchange factor rei-1 Antibody
Guanine nucleotide exchange factor for Rab GTPase Rab-11.1. Spatially and temporally regulates the distribution of Rab-11.1 to target membranes during embryogenesis. Plays a role in cytokinesis, probably by targeting rab-11.1 to the cleavage furrows.
 rei-1 ELISA Kit
 rei-1 Recombinant
 rei-1 Antibody
 C03C10.4 ELISA Kit
 C03C10.4 Recombinant
 C03C10.4 Antibody
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Guanine nucleotide exchange factor rei-2

 Guanine nucleotide exchange factor rei-2 ELISA Kit
 Guanine nucleotide exchange factor rei-2 Recombinant
 Guanine nucleotide exchange factor rei-2 Antibody
Guanine nucleotide exchange factor for Rab GTPase Rab-11.1 (). May spatially and temporally regulate the distribution of Rab-11.1 to target membranes during embryogenesis (PubMed:26506309). May play a role in cytokinesis, probably by targeting rab-11.1 to the cleavage furrows (PubMed:26506309).
 rei-2 ELISA Kit
 rei-2 Recombinant
 rei-2 Antibody
 K03E6.7 ELISA Kit
 K03E6.7 Recombinant
 K03E6.7 Antibody
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Guanine nucleotide exchange factor SDC25

 Guanine nucleotide exchange factor SDC25 ELISA Kit
 Guanine nucleotide exchange factor SDC25 Recombinant
 Guanine nucleotide exchange factor SDC25 Antibody
Promotes the exchange of Ras-bound GDP by GTP.
 SDC25 ELISA Kit
 SDC25 Recombinant
 SDC25 Antibody
 SCD25 ELISA Kit
 SCD25 Recombinant
 SCD25 Antibody
 SCRG_04972 ELISA Kit
 SCRG_04972 Recombinant
 SCRG_04972 Antibody
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Guanine nucleotide exchange factor SopE

 Guanine nucleotide exchange factor SopE ELISA Kit
 Guanine nucleotide exchange factor SopE Recombinant
 Guanine nucleotide exchange factor SopE Antibody
Also known as Guanine nucleotide exchange factor SopE (Effector protein SopE) (Toxin SopE).
Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells ().
 sopE ELISA Kit
 sopE Recombinant
 sopE Antibody
 STY4609 ELISA Kit
 STY4609 Recombinant
 STY4609 Antibody
 t4303 ELISA Kit
 t4303 Recombinant
 t4303 Antibody
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Guanine nucleotide exchange factor sopE2

 Guanine nucleotide exchange factor sopE2 ELISA Kit
 Guanine nucleotide exchange factor sopE2 Recombinant
 Guanine nucleotide exchange factor sopE2 Antibody
Also known as Guanine nucleotide exchange factor sopE2 (Effector protein sopE2) (Toxin sopE2).
Activator for CDC42 by directly engaging this Rho GTPase and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells. Also activates NF-kB, p38 and ERK
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kinases, which are known to be involved in the induction of IL-8 expression. Chaperone InvB is required for secretion, translocation and stabilization of intracellular levels of sopE2.
 sopE2 ELISA Kit
 sopE2 Recombinant
 sopE2 Antibody
 STM1855 ELISA Kit
 STM1855 Recombinant
 STM1855 Antibody
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Guanine nucleotide exchange factor SPIKE 1

 Guanine nucleotide exchange factor SPIKE 1 ELISA Kit
 Guanine nucleotide exchange factor SPIKE 1 Recombinant
 Guanine nucleotide exchange factor SPIKE 1 Antibody
Encodes SPIKE1 (SPK1), the lone DOCK family guanine nucleotide exchange factor (GEF) in Arabidopsis. SPK1 is a peripheral membrane protein that accumulates at, and promotes the formation of, a specialized domain of the endoplasmic reticulum (ER) termed the ER exit site (ERES). SPK1 promotes polarized growth and cell-cell adhesion in the leaf epidermis. Mutant has seedling lethal; cotyledon, leaf-shape, trichome defects.
 SPK1 ELISA Kit
 SPK1 Recombinant
 SPK1 Antibody
 At4g16340 ELISA Kit
 At4g16340 Recombinant
 At4g16340 Antibody
 dl4200c ELISA Kit
 dl4200c Recombinant
 dl4200c Antibody
 FCAALL.346 ELISA Kit
 FCAALL.346 Recombinant
 FCAALL.346 Antibody
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Guanine nucleotide exchange factor SRM1

 Guanine nucleotide exchange factor SRM1 ELISA Kit
 Guanine nucleotide exchange factor SRM1 Recombinant
 Guanine nucleotide exchange factor SRM1 Antibody
Also known as Guanine nucleotide exchange factor SRM1 (Pheromone response pathway component SRM1) (Pre-mRNA-processing protein 20) (Regulator of chromosome condensation) (Suppressor of receptor mutations 1) (mRNA transport protein 1).
Guanine nucleotide exchange factor that promotes the exchange of GSP1/GSP2-bound GDP by GTP and controls RNA metabolism and transport. Involved in yeast pheromone response pathway and in mRNA metabolism. Involved in nuclear pore complex (NPC) assembly and required for mRNA and ribosome nuclear export. Binds chromatin and is involved NPC-mediated transcriptiona
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l control.
 SRM1 ELISA Kit
 SRM1 Recombinant
 SRM1 Antibody
 MTR1 ELISA Kit
 MTR1 Recombinant
 MTR1 Antibody
 PRP20 ELISA Kit
 PRP20 Recombinant
 PRP20 Antibody
 YGL097W ELISA Kit
 YGL097W Recombinant
 YGL097W Antibody
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Guanine nucleotide exchange factor subunit R06F6.8

 Guanine nucleotide exchange factor subunit R06F6.8 ELISA Kit
 Guanine nucleotide exchange factor subunit R06F6.8 Recombinant
 Guanine nucleotide exchange factor subunit R06F6.8 Antibody
Also known as Guanine nucleotide exchange factor subunit R06F6.8 (Protein RIC1 homolog).
Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi.
 R06F6.8 ELISA Kit
 R06F6.8 Recombinant
 R06F6.8 Antibody
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Guanine nucleotide exchange factor subunit RGP1

 Guanine nucleotide exchange factor subunit RGP1 ELISA Kit
 Guanine nucleotide exchange factor subunit RGP1 Recombinant
 Guanine nucleotide exchange factor subunit RGP1 Antibody
Also known as Guanine nucleotide exchange factor subunit RGP1 (Reduced growth phenotype protein 1) (Rgp1p).
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates YPT6 by exchanging bound GDP for free GTP. It is thereby required for efficient fusion of endosome-derived vesicles with the Golgi. The RIC1-RGP1 participates in the recycling of SNC1, presumably by mediating fusion of endosomal vesicles with the Golgi compartment.
 RGP1 ELISA Kit
 RGP1 Recombinant
 RGP1 Antibody
 YDR137W ELISA Kit
 YDR137W Recombinant
 YDR137W Antibody
 YD9302.13 ELISA Kit
 YD9302.13 Recombinant
 YD9302.13 Antibody
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Guanine nucleotide exchange factor subunit ric1

 Guanine nucleotide exchange factor subunit ric1 ELISA Kit
 Guanine nucleotide exchange factor subunit ric1 Recombinant
 Guanine nucleotide exchange factor subunit ric1 Antibody
Also known as Guanine nucleotide exchange factor subunit ric1 (Protein ric1).
Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi.
 ric1 ELISA Kit
 ric1 Recombinant
 ric1 Antibody
 SPAC1851.04c ELISA Kit
 SPAC1851.04c Recombinant
 SPAC1851.04c Antibody
 SPAC27D7.01c ELISA Kit
 SPAC27D7.01c Recombinant
 SPAC27D7.01c Antibody
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Guanine nucleotide exchange factor subunit Rich

 Guanine nucleotide exchange factor subunit Rich ELISA Kit
 Guanine nucleotide exchange factor subunit Rich Recombinant
 Guanine nucleotide exchange factor subunit Rich Antibody
Also known as Guanine nucleotide exchange factor subunit Rich (Protein RIC1 homolog).
Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi (). Plays a role in regulating Rab6-dependent CadN transport in photoreceptor cells which is required for the formation of normal synaptic connections between a
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xons from the inner photoreceptor cells in the eye and postsynaptic cells in the brain medulla layer M6, and for the generation of normal postsynaptic responses.
 Rich ELISA Kit
 Rich Recombinant
 Rich Antibody
 CG9063 ELISA Kit
 CG9063 Recombinant
 CG9063 Antibody
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Guanine nucleotide exchange factor VAV2

 Guanine nucleotide exchange factor VAV2 ELISA Kit
 Guanine nucleotide exchange factor VAV2 Recombinant
 Guanine nucleotide exchange factor VAV2 Antibody
Also known as Guanine nucleotide exchange factor VAV2 (VAV-2).
VAV2: a proto-oncogenic guanine nucleotide exchange factors (GEF) of the Dbl family. A GEF for the Rho family of GTP binding proteins. Expressed in most tissues.

Protein type: GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis

Cellular Component: cytoplasm; plasma membrane
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Molecular Function: epidermal growth factor receptor binding; guanyl-nucleotide exchange factor activity; protein binding

Biological Process: cell migration; cell projection biogenesis; lamellipodium biogenesis; positive regulation of phosphoinositide 3-kinase activity; regulation of blood coagulation; regulation of gene expression; regulation of GTPase activity; small GTPase mediated signal transduction
 Vav2 ELISA Kit
 Vav2 Recombinant
 Vav2 Antibody
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Guanine nucleotide exchange factor VAV3

 Guanine nucleotide exchange factor VAV3 ELISA Kit
 Guanine nucleotide exchange factor VAV3 Recombinant
 Guanine nucleotide exchange factor VAV3 Antibody
Also known as Guanine nucleotide exchange factor VAV3 (VAV-3).
VAV3: a guanine nucleotide exchange factor (GEF) that activates RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitment by activated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migr
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ation and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2 (ITGB2)-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3 (ITGB3)-mediated adhesion. Does not affect integrin beta-1 (ITGB1)-mediated adhesion. Interacts with the PH domain of APS. Interacts (via SH2 domains) with the phosphorylated form of EPHA2. Interacts with ROS1; constitutive interaction that mediates VAV3 phosphorylation. Down-regulated by EGF and TGF-beta. Four isoforms of the human protein are produced by alternative promoter. Isoform 1 and isoform 3 are widely expressed; both are expressed at very low levels in skeletal muscle. In keratinocytes, isoform 1 is less abundant than isoform 3. Isoform 3 is detected at very low levels, if any, in adrenal gland, bone marrow, spleen, fetal brain and spinal chord; in these tissues, isoform 1 is readily detectable.

Protein type: Actin-binding; Adaptor/scaffold; GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis; Nuclear receptor co-regulator

Cellular Component: cytoplasm; plasma membrane

Molecular Function: epidermal growth factor receptor binding; guanyl-nucleotide exchange factor activity; protein binding; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity

Biological Process: B cell receptor signaling pathway; cell migration; cell projection biogenesis; integrin-mediated signaling pathway; lamellipodium biogenesis; neutrophil chemotaxis; positive regulation of B cell proliferation; positive regulation of cell adhesion; positive regulation of phosphoinositide 3-kinase activity; regulation of GTPase activity; response to DNA damage stimulus; response to drug; small GTPase mediated signal transduction; vesicle fusion
 Vav3 ELISA Kit
 Vav3 Recombinant
 Vav3 Antibody
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Guanine nucleotide-exchange factor SEC12

 Guanine nucleotide-exchange factor SEC12 ELISA Kit
 Guanine nucleotide-exchange factor SEC12 Recombinant
 Guanine nucleotide-exchange factor SEC12 Antibody
Also known as Guanine nucleotide-exchange factor SEC12 (Protein transport protein SEC12).
Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the small GTP-binding protein SAR1. Required for autophagy ().
 SEC12 ELISA Kit
 SEC12 Recombinant
 SEC12 Antibody
 CAGL0M10703g ELISA Kit
 CAGL0M10703g Recombinant
 CAGL0M10703g Antibody
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Guanine-nucleotide exchange factor YEL1

 Guanine-nucleotide exchange factor YEL1 ELISA Kit
 Guanine-nucleotide exchange factor YEL1 Recombinant
 Guanine-nucleotide exchange factor YEL1 Antibody
Guanine nucleotide exchange factor for ARF3 required for localization of ARF3 to the bud neck and tip and involved in actin patch polarization.
 YEL1 ELISA Kit
 YEL1 Recombinant
 YEL1 Antibody
 Kpol_1018p89 ELISA Kit
 Kpol_1018p89 Recombinant
 Kpol_1018p89 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
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