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H(+)/Cl(-) exchange transporter

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Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.

Below are the list of possible H(+)/Cl(-) exchange transporter products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

H(+)/Cl(-) exchange transporter 3

 H(+)/Cl(-) exchange transporter 3 ELISA Kit
 H(+)/Cl(-) exchange transporter 3 Recombinant
 H(+)/Cl(-) exchange transporter 3 Antibody
Also known as H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3).
CLCN3: Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function th
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rough regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory. Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, chloride; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel; Vesicle

Cellular Component: apical plasma membrane; cytoplasmic vesicle; early endosome; endosome; external side of plasma membrane; Golgi apparatus; integral to membrane; intracellular; late endosome; membrane; nerve terminal; phagocytic vesicle; plasma membrane; secretory granule; specific granule; synapse; synaptic vesicle; vesicle membrane

Molecular Function: chloride channel activity; chloride ion binding; ion channel activity; PDZ domain binding; protein heterodimerization activity; voltage-gated chloride channel activity; voltage-gated ion channel activity

Biological Process: adult locomotory behavior; chloride transport; endosomal lumen acidification; ion transport; negative regulation of cell volume; phagocytosis, engulfment; photoreceptor cell maintenance; synaptic transmission, GABAergic; synaptic transmission, glutamatergic
 Clcn3 ELISA Kit
 Clcn3 Recombinant
 Clcn3 Antibody
 Clc3 ELISA Kit
 Clc3 Recombinant
 Clc3 Antibody
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H(+)/Cl(-) exchange transporter 4

 H(+)/Cl(-) exchange transporter 4 ELISA Kit
 H(+)/Cl(-) exchange transporter 4 Recombinant
 H(+)/Cl(-) exchange transporter 4 Antibody
Also known as H(+)/Cl(-) exchange transporter 4 (Chloride channel protein 4) (ClC-4) (Chloride transporter ClC-4).
CLCN4: Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Belongs to the chloride channel (TC 2.A.49) family. ClC-4/CLCN4 subfamily.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporte
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r; Transporter, ion channel

Chromosomal Location of Human Ortholog: Xp22.3

Cellular Component: endoplasmic reticulum membrane; endosome membrane; integral to plasma membrane

Molecular Function: antiporter activity; chloride channel activity; chloride ion binding

Biological Process: chloride transport; transport

Disease: Mental Retardation, X-linked 49
 CLCN4 ELISA Kit
 CLCN4 Recombinant
 CLCN4 Antibody
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H(+)/Cl(-) exchange transporter 5

 H(+)/Cl(-) exchange transporter 5 ELISA Kit
 H(+)/Cl(-) exchange transporter 5 Recombinant
 H(+)/Cl(-) exchange transporter 5 Antibody
Also known as H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5).
Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function ().
 CLCN5 ELISA Kit
 CLCN5 Recombinant
 CLCN5 Antibody
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H(+)/Cl(-) exchange transporter 7

 H(+)/Cl(-) exchange transporter 7 ELISA Kit
 H(+)/Cl(-) exchange transporter 7 Recombinant
 H(+)/Cl(-) exchange transporter 7 Antibody
Also known as H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7).
CLCN7: Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen. Defects in CLCN7 are the cause of osteopetrosis autosomal recessive type 4 (OPTB4); also known as i
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nfantile malignant osteopetrosis type 2. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Defects in CLCN7 are the cause of osteopetrosis autosomal dominant type 2 (OPTA2); also known as autosomal dominant Albers-Schonberg disease or marble disease autosomal dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood. It is characterized by sclerosis, predominantly involving the spine, the pelvis and the skull base. Belongs to the chloride channel (TC 2.A.49) family. ClC-7/CLCN7 subfamily.

Protein type: Channel, chloride; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel

Cellular Component: cytoplasmic vesicle; lysosomal membrane; membrane

Biological Process: response to pH
 Clcn7 ELISA Kit
 Clcn7 Recombinant
 Clcn7 Antibody
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H(+)/Cl(-) exchange transporter ClcA

 H(+)/Cl(-) exchange transporter ClcA ELISA Kit
 H(+)/Cl(-) exchange transporter ClcA Recombinant
 H(+)/Cl(-) exchange transporter ClcA Antibody
Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
 clcA ELISA Kit
 clcA Recombinant
 clcA Antibody
 eriC ELISA Kit
 eriC Recombinant
 eriC Antibody
 ESA_03185 ELISA Kit
 ESA_03185 Recombinant
 ESA_03185 Antibody
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Proteins Root Name Listing
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