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Haptoglobin-related protein

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Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron.

Below are the list of possible Haptoglobin-related protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Haptoglobin-related protein

 Haptoglobin-related protein ELISA Kit
 Haptoglobin-related protein Recombinant
 Haptoglobin-related protein Antibody
HPR: a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. Th
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is protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: extracellular region

Biological Process: receptor-mediated endocytosis
 HPR ELISA Kit
 HPR Recombinant
 HPR Antibody
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