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Heart- and neural crest derivatives-expressed protein

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Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity).

Below are the list of possible Heart- and neural crest derivatives-expressed protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Heart- and neural crest derivatives-expressed protein 1

 Heart- and neural crest derivatives-expressed protein 1 ELISA Kit
 Heart- and neural crest derivatives-expressed protein 1 Recombinant
 Heart- and neural crest derivatives-expressed protein 1 Antibody
Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) ().
 HAND1 ELISA Kit
 HAND1 Recombinant
 HAND1 Antibody
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Heart- and neural crest derivatives-expressed protein 2

 Heart- and neural crest derivatives-expressed protein 2 ELISA Kit
 Heart- and neural crest derivatives-expressed protein 2 Recombinant
 Heart- and neural crest derivatives-expressed protein 2 Antibody
Also known as Heart- and neural crest derivatives-expressed protein 2 (Class A basic helix-loop-helix protein 26) (bHLHa26) (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).
HAND2: Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as a
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n upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 4q33

Cellular Component: nuclear chromatin; protein complex; transcription factor complex

Molecular Function: AT DNA binding; protein binding; protein homodimerization activity; transcription activator binding; transcription coactivator activity; transcription factor binding

Biological Process: adult heart development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of tissue remodeling; thymus development
 HAND2 ELISA Kit
 HAND2 Recombinant
 HAND2 Antibody
 BHLHA26 ELISA Kit
 BHLHA26 Recombinant
 BHLHA26 Antibody
 DHAND ELISA Kit
 DHAND Recombinant
 DHAND Antibody
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