Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Protein Family  rightarrow Hemojuvelin  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Cyclophilin F (PPIF) Recombinant Protein
 • HNF4 alpha Antibody
 • Augmenter of Liver Regeneration (ALR) ELISA Kit
 • Raf-1 (Ser301) (RAF1) Antibody
 • A4GNT cDNA Clone
 • transcobalamin II; macrocytic anemia (TCN2) Antibody
 • Cytosolic Phospholipase A2 (Cpla2) ELISA Kit
 • QTRTD1 Recombinant Protein
 • Myosin Heavy Chain 3, Skeletal Muscle, Embryonic (MYH3) ELISA Kit
 • Neurturin (NRTN) Antibody
 • Chrne Peptide
 • ORP11 - OSBPL11 Peptide
 • Osteoclase differentiation factor (ODF) ELISA Kit
 • SLC39A4 Antibody
 downarrow more ...
separator

Hemojuvelin

separator
Acts as a bone morphogenetic protein (BMP) coreceptor. Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis.

Below are the list of possible Hemojuvelin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Hemojuvelin

 Hemojuvelin ELISA Kit
 Hemojuvelin Recombinant
 Hemojuvelin Antibody
Also known as Hemojuvelin (Hemochromatosis type 2 protein homolog) (RGM domain family member C).
HFE2: Member of the repulsive guidance molecule (RGM) family. Involved in iron metabolism. Acts as a bone morphogenetic protein (BMP) coreceptor. Enhancement of BMP signaling regulates hepcidin (HAMP) expression and iron metabolism. May cooperate with hepcidin to restrict iron absorption in the gut.
>>>
Could represent the cellular receptor for hepcidin. Defects in HFE2 are the cause of hemochromatosis type 2A (HFE2A); also known as juvenile hemochromatosis (JH). HFE2A is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. It is the consequence of intestinal iron hyperabsorption associated with macrophages that do not load iron. Deleterious mutations of HFE2 reduced HAMP (hepcidin) levels despite iron overload, which normally induces HAMP expression. Belongs to the repulsive guidance molecule (RGM) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor

Cellular Component: basolateral plasma membrane; cell surface; extracellular space; plasma membrane

Molecular Function: coreceptor activity; glycoprotein binding; receptor binding

Biological Process: activin receptor signaling pathway; BMP signaling pathway; cellular iron ion homeostasis; iron ion homeostasis; negative regulation of BMP signaling pathway; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein autoprocessing
 Hfe2 ELISA Kit
 Hfe2 Recombinant
 Hfe2 Antibody
 Rgmc ELISA Kit
 Rgmc Recombinant
 Rgmc Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions