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Heparan-alpha-glucosaminide N-acetyltransferase

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Lysosomal acetyltransferase that acetylates the non-reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase.

Below are the list of possible Heparan-alpha-glucosaminide N-acetyltransferase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Heparan-alpha-glucosaminide N-acetyltransferase

 Heparan-alpha-glucosaminide N-acetyltransferase ELISA Kit
 Heparan-alpha-glucosaminide N-acetyltransferase Recombinant
 Heparan-alpha-glucosaminide N-acetyltransferase Antibody
Also known as Heparan-alpha-glucosaminide N-acetyltransferase (Transmembrane protein 76).
HGSNAT: Lysosomal acetyltransferase that acetylates the non- reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase. Defects in HGSNAT are the cause of mucopolysaccharidosis type 3C (MPS3C); also known as Sanfilippo C syndrome. MPS3C is a form of mucopolysaccharidosis type 3, an autosomal recessive lysosomal storage disease due to impaired degradation of heparan sulfate. MPS3 is characterized by
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severe central nervous system degeneration, but only mild somatic disease. Onset of clinical features usually occurs between 2 and 6 years; severe neurologic degeneration occurs in most patients between 6 and 10 years of age, and death occurs typically during the second or third decade of life. 2 isoforms of the human protein are produced by alternative initiation.

Protein type: Acetyltransferase; EC 2.3.1.78; Glycan Metabolism - glycosaminoglycan degradation; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: lysosomal membrane

Molecular Function: transferase activity, transferring acyl groups

Biological Process: lysosomal transport; protein oligomerization
 Hgsnat ELISA Kit
 Hgsnat Recombinant
 Hgsnat Antibody
 D8Ertd354e ELISA Kit
 D8Ertd354e Recombinant
 D8Ertd354e Antibody
 Tmem76 ELISA Kit
 Tmem76 Recombinant
 Tmem76 Antibody
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