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Histone H4 transcription factor

Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter.

Below are the list of possible Histone H4 transcription factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Histone H4 transcription factor

 Histone H4 transcription factor ELISA Kit
 Histone H4 transcription factor Recombinant
 Histone H4 transcription factor Antibody
Also known as Histone H4 transcription factor (Histone nuclear factor P) (HiNF-P) (MBD2-interacting zinc finger protein) (Methyl-CpG-binding protein 2-interacting zinc finger protein).
MIZF: a transcriptional regulator of cell cycle-controlled histone H4 genes at the onset of S phase. Also activates transcription of the ATM and PRKDC genes. A histone H4-specific transcriptional regulator that a
ssociates with the cell cycle control element in the conserved proximal promoter regions of H4 genes. Interacts with NPAT to coactivate H4 gene transcription at the G1/S phase transition in response to cyclin E/CDK2 signaling. HiNF-P/NPAT colocalize to Cajal bodies in a cell cycle-specific manner. Disruption of the HiNF-P/NPAT interaction inhibits histone H4 gene expression at G1/S. Binds methyl-CpG-binding protein (MeCP2) and a histone deacetylase complex.

Protein type: C2H2-type zinc finger protein; Cell cycle regulation; Histone-binding

Cellular Component: Cajal body; nucleoplasm; nucleus

Molecular Function: chromatin binding; DNA binding; enzyme binding; histone binding; transcription coactivator activity; transcription factor activity

Biological Process: DNA damage checkpoint; DNA repair; establishment of protein localization; G1/S transition of mitotic cell cycle; G1/S-specific transcription in mitotic cell cycle; in utero embryonic development; myoblast differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of gene expression; regulation of transcription, DNA-dependent; transcription, DNA-dependent
 Hinfp ELISA Kit
 Hinfp Recombinant
 Hinfp Antibody
 Mizf ELISA Kit
 Mizf Recombinant
 Mizf Antibody
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