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Homer protein

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Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2 (By similarity).

Below are the list of possible Homer protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Homer protein homolog 1

 Homer protein homolog 1 ELISA Kit
 Homer protein homolog 1 Recombinant
 Homer protein homolog 1 Antibody
Also known as Homer protein homolog 1 (Homer-1).
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interactio
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n with AGAP2 ().
 HOMER1 ELISA Kit
 HOMER1 Recombinant
 HOMER1 Antibody
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Homer protein homolog 2

 Homer protein homolog 2 ELISA Kit
 Homer protein homolog 2 Recombinant
 Homer protein homolog 2 Antibody
Also known as Homer protein homolog 2 (Homer-2) (Cupidin).
HOMER2: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase thro
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ugh its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. Belongs to the Homer family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Actin-binding; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 15q24.3

Cellular Component: cell junction; cytoplasm; nucleolus; nucleus; plasma membrane; stereocilium bundle tip

Molecular Function: metabotropic glutatmate receptor binding; protein binding

Biological Process: metabotropic glutamate receptor signaling pathway; sensory perception of sound

Disease: Deafness, Autosomal Dominant 68
 HOMER2 ELISA Kit
 HOMER2 Recombinant
 HOMER2 Antibody
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Homer protein homolog 3

 Homer protein homolog 3 ELISA Kit
 Homer protein homolog 3 Recombinant
 Homer protein homolog 3 Antibody
Also known as Homer protein homolog 3 (Homer-3).
HOMER3: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may pla
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y an important role in maintaining the plasticity at glutamatergic synapses. Belongs to the Homer family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: cytoplasm; plasma membrane

Molecular Function: metabotropic glutatmate receptor binding; protein binding

Biological Process: metabotropic glutamate receptor signaling pathway; protein targeting
 HOMER3 ELISA Kit
 HOMER3 Recombinant
 HOMER3 Antibody
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