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Hydroxycarboxylic acid receptor

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Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway.

Below are the list of possible Hydroxycarboxylic acid receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Hydroxycarboxylic acid receptor 1

 Hydroxycarboxylic acid receptor 1 ELISA Kit
 Hydroxycarboxylic acid receptor 1 Recombinant
 Hydroxycarboxylic acid receptor 1 Antibody
Also known as Hydroxycarboxylic acid receptor 1 (G-protein coupled receptor 104) (G-protein coupled receptor 81).
Gpr81: Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: plasma membrane
 HCAR1 ELISA Kit
 HCAR1 Recombinant
 HCAR1 Antibody
 GPR104 ELISA Kit
 GPR104 Recombinant
 GPR104 Antibody
 GPR81 ELISA Kit
 GPR81 Recombinant
 GPR81 Antibody
 HCA1 ELISA Kit
 HCA1 Recombinant
 HCA1 Antibody
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Hydroxycarboxylic acid receptor 2

 Hydroxycarboxylic acid receptor 2 ELISA Kit
 Hydroxycarboxylic acid receptor 2 Recombinant
 Hydroxycarboxylic acid receptor 2 Antibody
Also known as Hydroxycarboxylic acid receptor 2 (G-protein coupled receptor 109) (G-protein coupled receptor 109A) (G-protein coupled receptor HM74) (Niacin receptor 1) (Nicotinic acid receptor) (Protein PUMA-G).
GPR109A: Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic
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acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis. The rank order of potency for the displacement of nicotinic acid binding is 5- methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: cell junction; integral to membrane; plasma membrane

Molecular Function: GTP binding; purinergic nucleotide receptor activity

Biological Process: negative regulation of lipid catabolic process; neutrophil apoptosis; positive regulation of neutrophil apoptosis
 Hcar2 ELISA Kit
 Hcar2 Recombinant
 Hcar2 Antibody
 Gpr109 ELISA Kit
 Gpr109 Recombinant
 Gpr109 Antibody
 Gpr109a ELISA Kit
 Gpr109a Recombinant
 Gpr109a Antibody
 Gpr109b ELISA Kit
 Gpr109b Recombinant
 Gpr109b Antibody
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Hydroxycarboxylic acid receptor 3

 Hydroxycarboxylic acid receptor 3 ELISA Kit
 Hydroxycarboxylic acid receptor 3 Recombinant
 Hydroxycarboxylic acid receptor 3 Antibody
Also known as Hydroxycarboxylic acid receptor 3 (G-protein coupled receptor 109B) (G-protein coupled receptor HM74) (G-protein coupled receptor HM74B) (Niacin receptor 2) (Nicotinic acid receptor 2).
GPR109B: Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. B
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elongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: cell junction; integral to plasma membrane; plasma membrane
 HCAR3 ELISA Kit
 HCAR3 Recombinant
 HCAR3 Antibody
 GPR109B ELISA Kit
 GPR109B Recombinant
 GPR109B Antibody
 HCA3 ELISA Kit
 HCA3 Recombinant
 HCA3 Antibody
 HM74B ELISA Kit
 HM74B Recombinant
 HM74B Antibody
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