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Immunity-related GTPase family M protein

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Putative GTPase which is required for IFNG-mediated clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility (By similarity).

Below are the list of possible Immunity-related GTPase family M protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Immunity-related GTPase family M protein

 Immunity-related GTPase family M protein ELISA Kit
 Immunity-related GTPase family M protein Recombinant
 Immunity-related GTPase family M protein Antibody
IRGM: Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility. Defects in IRGM are the cause of susceptibility to inflammatory bowel disea
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se type 19 (IBD19). A chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. Belongs to the interferon-inducible GTPase family.

Protein type: EC 3.6.5.-; Endoplasmic reticulum; Hydrolase

Cellular Component: endoplasmic reticulum membrane; late endosome; lysosome

Molecular Function: GTPase activity

Biological Process: defense response
 Irgm ELISA Kit
 Irgm Recombinant
 Irgm Antibody
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Immunity-related GTPase family M protein 1

 Immunity-related GTPase family M protein 1 ELISA Kit
 Immunity-related GTPase family M protein 1 Recombinant
 Immunity-related GTPase family M protein 1 Antibody
Also known as Immunity-related GTPase family M protein 1 (Interferon-inducible GTPase 3) (Interferon-inducible protein 1) (LPS-stimulated RAW 264.7 macrophage protein 47) (LRG-47).
IRGM: Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility. Defects in IRGM are the cause of susceptibility to inflammatory bowel disease type 19 (IBD1
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9). A chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. Belongs to the interferon-inducible GTPase family.

Protein type: EC 3.6.5.-; Endoplasmic reticulum; Hydrolase

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; late endosome; lysosome

Molecular Function: GTPase activity

Biological Process: defense response
 Irgm1 ELISA Kit
 Irgm1 Recombinant
 Irgm1 Antibody
 Ifi1 ELISA Kit
 Ifi1 Recombinant
 Ifi1 Antibody
 Iigp3 ELISA Kit
 Iigp3 Recombinant
 Iigp3 Antibody
 Irgm ELISA Kit
 Irgm Recombinant
 Irgm Antibody
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