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Indole diterpene prenyltransferase

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Indole diterpene prenyltransferase; part of the ATM2 gene cluster that mediates the biosynthesis of aflatrem, a tremorgenic mycotoxin with acute neurotoxic effects .

Below are the list of possible Indole diterpene prenyltransferase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Indole diterpene prenyltransferase atmD

 Indole diterpene prenyltransferase atmD ELISA Kit
 Indole diterpene prenyltransferase atmD Recombinant
 Indole diterpene prenyltransferase atmD Antibody
Also known as Indole diterpene prenyltransferase atmD (Aflatrem synthesis protein D).
Indole diterpene prenyltransferase; part of the ATM2 gene cluster that mediates the biosynthesis of aflatrem, a tremorgenic mycotoxin with acute neurotoxic effects (PubMed:19801473, PubMed:2867895). Synthesis of geranylgeranyl diphosphate (GGPP) by AtmG (a GGPP synthase) precedes condensation of GGPP with indo
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le 3-glycerol phosphate, followed by epoxidation and cyclization by AtmM (a FAD-dependent monooxygenase) and AtmC (a prenyltransferase) to produce paspaline (PubMed:19801473). AtmB is also essential for paspaline production, but its exact role has not been identified yet (PubMed:19801473). AtmP, a cytochrome P450 monooxygenase, subsequently converts paspaline to 13-desoxypaxilline via PC-M6 by removal of the C-30 methyl group and oxidation at C-10 (PubMed:19801473). AtmQ, a cytochrome P450 monooxygenase, then catalyzes the oxidation of 13-desoxypaxilline, first at C-7 to produce paspalicine and then at C-13 to form paspalinine (PubMed:19801473). Finally, AtmD prenylates paspalinine to form aflatrem (PubMed:19801473, PubMed:24038699).
 atmD ELISA Kit
 atmD Recombinant
 atmD Antibody
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Indole diterpene prenyltransferase pax

 Indole diterpene prenyltransferase pax ELISA Kit
 Indole diterpene prenyltransferase pax Recombinant
 Indole diterpene prenyltransferase pax Antibody
Also known as Indole diterpene prenyltransferase pax (Paxilline synthesis protein D).
Indole diterpene prenyltransferase; part of the gene cluster that mediates the biosynthesis of paxilline, a mycotoxin that acts as an inhibitor of mammalian maxi-K channels (PubMed:11169115, PubMed:23949005). PaxG, the geranylgeranyl diphosphate (GGPP) synthase is proposed to catalyze the first step in paxilli
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ne biosynthesis (PubMed:23949005). Condensation of indole-3-glycerol phosphate with GGPP by paxC then forms 3-geranylgeranylindole (3-GGI), followed by epoxidation and cyclization of this intermediate (by paxM and paxB) to form paspaline (PubMed:23949005). Paspaline is subsequently converted to 13-desoxypaxilline by paxP, the latter being then converted to paxilline by paxQ (PubMed:23949005). Finally paxilline can be mono- and di-prenylated by paxD (PubMed:23949005).
 paxD ELISA Kit
 paxD Recombinant
 paxD Antibody
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