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Inositol-trisphosphate 3-kinase

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CATALYTIC ACTIVITY: ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.ENZYME REGULATION: IP3K is activated by calmodulin.

Below are the list of possible Inositol-trisphosphate 3-kinase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Inositol-trisphosphate 3-kinase A

 Inositol-trisphosphate 3-kinase A ELISA Kit
 Inositol-trisphosphate 3-kinase A Recombinant
 Inositol-trisphosphate 3-kinase A Antibody
Also known as Inositol-trisphosphate 3-kinase A (Inositol 1,4,5-trisphosphate 3-kinase A) (IP3 3-kinase A) (IP3K A) (InsP 3-kinase A).
ITPKA: Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol
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polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011]

Protein type: Carbohydrate Metabolism - inositol phosphate; EC 2.7.1.127; Kinase, lipid; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 15q15.1

Cellular Component: cytosol

Molecular Function: inositol trisphosphate 3-kinase activity

Biological Process: inositol phosphate metabolic process; signal transduction
 ITPKA ELISA Kit
 ITPKA Recombinant
 ITPKA Antibody
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Inositol-trisphosphate 3-kinase B

 Inositol-trisphosphate 3-kinase B ELISA Kit
 Inositol-trisphosphate 3-kinase B Recombinant
 Inositol-trisphosphate 3-kinase B Antibody
Also known as Inositol-trisphosphate 3-kinase B (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B).
ITPKB: The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large num
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ber of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq, Jul 2008]

Protein type: Carbohydrate Metabolism - inositol phosphate; EC 2.7.1.127; Kinase, lipid; Motility/polarity/chemotaxis

Cellular Component: cytosol; membrane; nucleus

Molecular Function: inositol trisphosphate 3-kinase activity

Biological Process: cell surface receptor linked signal transduction; inositol trisphosphate metabolic process; MAPKKK cascade; myeloid cell homeostasis; negative regulation of myeloid cell differentiation; negative regulation of neutrophil apoptosis; positive regulation of alpha-beta T cell differentiation; positive regulation of Ras protein signal transduction; positive thymic T cell selection; regulation of protein amino acid phosphorylation; T cell differentiation; thymic T cell selection
 Itpkb ELISA Kit
 Itpkb Recombinant
 Itpkb Antibody
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Inositol-trisphosphate 3-kinase C

 Inositol-trisphosphate 3-kinase C ELISA Kit
 Inositol-trisphosphate 3-kinase C Recombinant
 Inositol-trisphosphate 3-kinase C Antibody
Also known as Inositol-trisphosphate 3-kinase C (Inositol 1,4,5-trisphosphate 3-kinase C) (IP3 3-kinase C) (IP3K C) (InsP 3-kinase C).
ITPKC: Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate. Defects in ITPKC are a cause of Kawasaki disease (KWD); also known as mucocutaneous lymph node syndrome or infantile polyarteritis. Kawasaki disease is an acute, self- limit
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ed vasculitis of infants and children characterized by prolonged fever unresponsive to antibiotics, polymorphous skin rash, erythema of the oral mucosa, lips, and tongue, erythema of the palms and soles, bilateral conjunctival injection, and cervical lymphadenopathy. Coronary artery aneurysms develop in 15 to 25% of those left untreated, making Kawasaki disease the leading cause of acquired heart disease among children in developed countries. Belongs to the inositol phosphokinase (IPK) family.

Protein type: EC 2.7.1.127; Kinase, lipid; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: cytosol; nucleoplasm

Molecular Function: inositol trisphosphate 3-kinase activity

Biological Process: inositol phosphate metabolic process

Disease: Kawasaki Disease
 ITPKC ELISA Kit
 ITPKC Recombinant
 ITPKC Antibody
 IP3KC ELISA Kit
 IP3KC Recombinant
 IP3KC Antibody
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Inositol-trisphosphate 3-kinase homolog

 Inositol-trisphosphate 3-kinase homolog ELISA Kit
 Inositol-trisphosphate 3-kinase homolog Recombinant
 Inositol-trisphosphate 3-kinase homolog Antibody
Also known as Inositol-trisphosphate 3-kinase homolog (Inositol 1,4,5-trisphosphate 3-kinase homolog) (IP3 3-kinase) (IP3K) (InsP 3-kinase) (let-23 fertility effector 2).
Probably by regulating inositol 1,4,5-trisphosphate levels, negatively regulates posterior body wall muscle contractions required for defecation and let-23 signaling pathway that controls spermathecal dilation and ovulation (P
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ubMed:9491893, PubMed:16186564). May also regulate ovulation downstream of actin cross-linker fln-1 (PubMed:23671426).
 lfe-2 ELISA Kit
 lfe-2 Recombinant
 lfe-2 Antibody
 C46H11.4 ELISA Kit
 C46H11.4 Recombinant
 C46H11.4 Antibody
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