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Interferon alpha/beta receptor

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Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 .

Below are the list of possible Interferon alpha/beta receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Interferon alpha/beta receptor 1

 Interferon alpha/beta receptor 1 ELISA Kit
 Interferon alpha/beta receptor 1 Recombinant
 Interferon alpha/beta receptor 1 Antibody
Also known as Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Cytokine receptor class-II member 1) (Cytokine receptor family 2 member 1) (CRF2-1) (Type I interferon receptor 1).
IFNAR1: receptor for interferons alpha and beta. Belongs to the type II cytokine family of receptors. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JA
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Ks, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Tyk2 tyrosine kinase is essential for stable cell surface expression of IFNAR1. Present in all tissues and even on the surface of most IFN-resistant cells.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 21q22.11

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: interferon-alpha/beta binding; interferon-alpha/beta receptor activity; protein binding

Biological Process: JAK-STAT cascade; response to lipopolysaccharide; response to virus
 IFNAR1 ELISA Kit
 IFNAR1 Recombinant
 IFNAR1 Antibody
 IFNAR ELISA Kit
 IFNAR Recombinant
 IFNAR Antibody
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Interferon alpha/beta receptor 1a

 Interferon alpha/beta receptor 1a ELISA Kit
 Interferon alpha/beta receptor 1a Recombinant
 Interferon alpha/beta receptor 1a Antibody
Also known as Interferon alpha/beta receptor 1a (Membrane-associated type I interferon receptor) (mIFNAR1) (Type I interferon receptor 1a).
Involved in antiviral response. Associates with IFNAR2 to form the type I interferon receptor.
 ifnar1a ELISA Kit
 ifnar1a Recombinant
 ifnar1a Antibody
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Interferon alpha/beta receptor 1b

 Interferon alpha/beta receptor 1b ELISA Kit
 Interferon alpha/beta receptor 1b Recombinant
 Interferon alpha/beta receptor 1b Antibody
Also known as Interferon alpha/beta receptor 1b (Intracellular type I interferon receptor) (iIFNAR1).
Involved in antiviral response. Associates with IFNAR2 to form the type I interferon receptor. In the presence of intracellular IFNAR1 (IFNAR1B) and IFNA1 (iIFN1b isoform), may mediate STAT1 and STAT2 phosphorylation and induction of EIF2AK2, MX1 and RSAD2.
 ifnar1b ELISA Kit
 ifnar1b Recombinant
 ifnar1b Antibody
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Interferon alpha/beta receptor 2

 Interferon alpha/beta receptor 2 ELISA Kit
 Interferon alpha/beta receptor 2 Recombinant
 Interferon alpha/beta receptor 2 Antibody
Also known as Interferon alpha/beta receptor 2 (IFN-R-2) (IFN-alpha binding protein) (IFN-alpha/beta receptor 2) (Interferon alpha binding protein) (Type I interferon receptor 2).
IFNAR2: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity. Belongs to the type II cytokine receptor family. 3 isoforms
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of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 21q22.11

Cellular Component: extracellular region; integral to plasma membrane; plasma membrane

Molecular Function: interferon-alpha/beta receptor activity; interleukin-20 binding; protein binding; protein kinase binding

Biological Process: cell surface receptor linked signal transduction; defense response to virus; JAK-STAT cascade; response to virus

Disease: Hepatitis B Virus, Susceptibility To; Immunodeficiency 45
 IFNAR2 ELISA Kit
 IFNAR2 Recombinant
 IFNAR2 Antibody
 IFNABR ELISA Kit
 IFNABR Recombinant
 IFNABR Antibody
 IFNARB ELISA Kit
 IFNARB Recombinant
 IFNARB Antibody
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