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Interferon alpha/beta receptor 2 ELISA Kit Interferon alpha/beta receptor 2 Recombinant Interferon alpha/beta receptor 2 Antibody | Also known as Interferon alpha/beta receptor 2 (IFN-R-2) (IFN-alpha binding protein) (IFN-alpha/beta receptor 2) (Interferon alpha binding protein) (Type I interferon receptor 2). IFNAR2: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity. Belongs to the type II cytokine receptor family. 3 isoforms >>> of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, cytokine
Chromosomal Location of Human Ortholog: 21q22.11
Cellular Component: extracellular region; integral to plasma membrane; plasma membrane
Molecular Function: interferon-alpha/beta receptor activity; interleukin-20 binding; protein binding; protein kinase binding
Biological Process: cell surface receptor linked signal transduction; defense response to virus; JAK-STAT cascade; response to virus
Disease: Hepatitis B Virus, Susceptibility To; Immunodeficiency 45 |
IFNAR2 ELISA Kit IFNAR2 Recombinant IFNAR2 Antibody | IFNABR ELISA Kit IFNABR Recombinant IFNABR Antibody |
IFNARB ELISA Kit IFNARB Recombinant IFNARB Antibody |
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