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Interferon-induced transmembrane protein

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IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV) and West Nile virus (WNV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.

Below are the list of possible Interferon-induced transmembrane protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Interferon-induced transmembrane protein 1

 Interferon-induced transmembrane protein 1 ELISA Kit
 Interferon-induced transmembrane protein 1 Recombinant
 Interferon-induced transmembrane protein 1 Antibody
Also known as Interferon-induced transmembrane protein 1 (Dispanin subfamily A member 2a) (DSPA2a) (Fragilis protein 2) (Mouse ifitm-like protein 2) (Mil-2).
IFITM1: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple vi
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ruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV) and West Nile virus (WNV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation

Protein type: Cell cycle regulation; Membrane protein, integral; Membrane protein, multi-pass

Biological Process: anterior/posterior pattern formation; defense response to virus; negative regulation of virion penetration into host cell; response to virus; somitogenesis
 Ifitm1 ELISA Kit
 Ifitm1 Recombinant
 Ifitm1 Antibody
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Interferon-induced transmembrane protein 10

 Interferon-induced transmembrane protein 10 ELISA Kit
 Interferon-induced transmembrane protein 10 Recombinant
 Interferon-induced transmembrane protein 10 Antibody
Also known as Interferon-induced transmembrane protein 10 (Dispanin subfamily A member 3) (DSPA3).
IFITM10: Belongs to the CD225/Dispanin family

Protein type: Membrane protein, integral; Membrane protein, multi-pass
 Ifitm10 ELISA Kit
 Ifitm10 Recombinant
 Ifitm10 Antibody
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Interferon-induced transmembrane protein 2

 Interferon-induced transmembrane protein 2 ELISA Kit
 Interferon-induced transmembrane protein 2 Recombinant
 Interferon-induced transmembrane protein 2 Antibody
Also known as Interferon-induced transmembrane protein 2 (Dispanin subfamily A member 2c) (DSPA2c) (Fragilis protein 3).
IFITM2: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, S
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ARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein- mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. Belongs to the CD225/Dispanin family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Biological Process: defense response to virus; negative regulation of viral genome replication; negative regulation of virion penetration into host cell; response to virus
 Ifitm2 ELISA Kit
 Ifitm2 Recombinant
 Ifitm2 Antibody
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Interferon-induced transmembrane protein 3

 Interferon-induced transmembrane protein 3 ELISA Kit
 Interferon-induced transmembrane protein 3 Recombinant
 Interferon-induced transmembrane protein 3 Antibody
Also known as Interferon-induced transmembrane protein 3 (Dispanin subfamily A member 2b) (DSPA2b).
IFITM3: IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. Interacts with SPP1; the interaction reduces OPN expr
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ession. By IFN-alpha and IFNG/IFN-gamma. Belongs to the CD225/Dispanin family.

Protein type: Cell surface; Membrane protein, integral

Cellular Component: apical part of cell; cell surface; cytoplasm; cytoplasmic vesicle; endoplasmic reticulum; nucleus; plasma membrane

Biological Process: cardiac muscle cell differentiation; defense response to virus; heart development; negative regulation of cell proliferation; negative regulation of viral genome replication; negative regulation of viral transcription; negative regulation of virion penetration into host cell; receptor-mediated endocytosis; response to virus
 ifitm3 ELISA Kit
 ifitm3 Recombinant
 ifitm3 Antibody
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Interferon-induced transmembrane protein 5

 Interferon-induced transmembrane protein 5 ELISA Kit
 Interferon-induced transmembrane protein 5 Recombinant
 Interferon-induced transmembrane protein 5 Antibody
Also known as Interferon-induced transmembrane protein 5 (Bone-restricted interferon-induced transmembrane protein-like protein) (BRIL) (Dispanin subfamily A member 1) (DSPA1).
IFITM5: Plays a role in bone mineralization. Belongs to the CD225/Dispanin family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 11p15.5
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br>Cellular Component: integral to plasma membrane

Biological Process: bone mineralization

Disease: Osteogenesis Imperfecta, Type V
 IFITM5 ELISA Kit
 IFITM5 Recombinant
 IFITM5 Antibody
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