| Interleukin-1 receptor accessory protein-like 1 ELISA Kit|
Interleukin-1 receptor accessory protein-like 1 Recombinant
Interleukin-1 receptor accessory protein-like 1 Antibody
|Also known as Interleukin-1 receptor accessory protein-like 1 (IL-1-RAPL-1) (IL-1RAPL-1) (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2) (X-linked interleukin-1 receptor accessory protein-like 1). |
IL1RAPL1: May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. Ma
y activate the MAP kinase JNK. Plays a role in presynaptic and postsynaptic differentiation and dendritic spine formation in neurons. Defects in IL1RAPL1 are the cause of mental retardation X-linked type 21 (MRX21). Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non- syndromic mental retardation patients do not manifest other clinical signs. Belongs to the interleukin-1 receptor family. 1 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: Xp22.1-p21.3
Cellular Component: cell surface; dendrite; plasma membrane
Molecular Function: interleukin-1 binding; protein binding; receptor binding; voltage-gated calcium channel activity
Biological Process: heterophilic cell adhesion; negative regulation of exocytosis; neuron differentiation; positive regulation of dendrite morphogenesis
Disease: Mental Retardation, X-linked 21
| IL1RAPL1 ELISA Kit|
| OPHN4 ELISA Kit|