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Interleukin-1 receptor accessory protein

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Coreceptor for IL1RL2 in the IL-36 signaling system (By similarity). Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone; binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor. Coreceptor for IL1RL1 in the IL-33 signaling system (By similarity).

Below are the list of possible Interleukin-1 receptor accessory protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Interleukin-1 receptor accessory protein

 Interleukin-1 receptor accessory protein ELISA Kit
 Interleukin-1 receptor accessory protein Recombinant
 Interleukin-1 receptor accessory protein Antibody
Also known as Interleukin-1 receptor accessory protein (IL-1 receptor accessory protein) (IL-1RAcP).
facilitates the binding between interleukin-1 and its receptor [RGD, Feb 2006]
 Il1rap ELISA Kit
 Il1rap Recombinant
 Il1rap Antibody
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Interleukin-1 receptor accessory protein-like 1

 Interleukin-1 receptor accessory protein-like 1 ELISA Kit
 Interleukin-1 receptor accessory protein-like 1 Recombinant
 Interleukin-1 receptor accessory protein-like 1 Antibody
Also known as Interleukin-1 receptor accessory protein-like 1 (IL-1-RAPL-1) (IL-1RAPL-1) (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2) (X-linked interleukin-1 receptor accessory protein-like 1).
IL1RAPL1: May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. Ma
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y activate the MAP kinase JNK. Plays a role in presynaptic and postsynaptic differentiation and dendritic spine formation in neurons. Defects in IL1RAPL1 are the cause of mental retardation X-linked type 21 (MRX21). Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non- syndromic mental retardation patients do not manifest other clinical signs. Belongs to the interleukin-1 receptor family. 1 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: Xp22.1-p21.3

Cellular Component: cell surface; dendrite; plasma membrane

Molecular Function: interleukin-1 binding; protein binding; receptor binding; voltage-gated calcium channel activity

Biological Process: heterophilic cell adhesion; negative regulation of exocytosis; neuron differentiation; positive regulation of dendrite morphogenesis

Disease: Mental Retardation, X-linked 21
 IL1RAPL1 ELISA Kit
 IL1RAPL1 Recombinant
 IL1RAPL1 Antibody
 OPHN4 ELISA Kit
 OPHN4 Recombinant
 OPHN4 Antibody
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Interleukin-1 receptor accessory protein-like 1-A

 Interleukin-1 receptor accessory protein-like 1-A ELISA Kit
 Interleukin-1 receptor accessory protein-like 1-A Recombinant
 Interleukin-1 receptor accessory protein-like 1-A Antibody
May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. During presynaptic differentiation may regulate both synaptic vesicle accumulation in axon terminals and subsequent axon terminal remodeling.
 il1rapl1a ELISA Kit
 il1rapl1a Recombinant
 il1rapl1a Antibody
 zgc:152866 ELISA Kit
 zgc:152866 Recombinant
 zgc:152866 Antibody
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Interleukin-1 receptor accessory protein-like 1-B

 Interleukin-1 receptor accessory protein-like 1-B ELISA Kit
 Interleukin-1 receptor accessory protein-like 1-B Recombinant
 Interleukin-1 receptor accessory protein-like 1-B Antibody
May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. During presynaptic differentiation may regulate both synaptic vesicle accumulation in axon terminals and subsequent axon terminal remodeling.
 il1rapl1b ELISA Kit
 il1rapl1b Recombinant
 il1rapl1b Antibody
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