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Interleukin-10 receptor

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Receptor for IL10; binds IL10 with a high affinity.

Below are the list of possible Interleukin-10 receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Interleukin-10 receptor subunit alpha

 Interleukin-10 receptor subunit alpha ELISA Kit
 Interleukin-10 receptor subunit alpha Recombinant
 Interleukin-10 receptor subunit alpha Antibody
Also known as Interleukin-10 receptor subunit alpha (IL-10 receptor subunit alpha) (IL-10R subunit alpha) (IL-10RA) (CDw210a) (Interleukin-10 receptor subunit 1) (IL-10R subunit 1) (IL-10R1) (CD antigen CD210).
IL10RA: a receptor for interleukin 10 structurally related to interferon receptors. Mediates the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflamm
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atory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.

Protein type: Membrane protein, integral; Receptor, cytokine

Cellular Component: integral to membrane; plasma membrane

Molecular Function: interleukin-10 binding; interleukin-10 receptor activity

Biological Process: regulation of synapse organization and biogenesis
 Il10ra ELISA Kit
 Il10ra Recombinant
 Il10ra Antibody
 Il10r ELISA Kit
 Il10r Recombinant
 Il10r Antibody
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Interleukin-10 receptor subunit beta

 Interleukin-10 receptor subunit beta ELISA Kit
 Interleukin-10 receptor subunit beta Recombinant
 Interleukin-10 receptor subunit beta Antibody
Also known as Interleukin-10 receptor subunit beta (IL-10 receptor subunit beta) (IL-10R subunit beta) (IL-10RB) (Cytokine receptor class-II member 4) (Cytokine receptor family 2 member 4) (CRF2-4) (Interleukin-10 receptor subunit 2) (IL-10R subunit 2) (IL-10R2) (CD antigen CDw210b).
IL10RB: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL
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28, and IL29. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25). It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. Belongs to the type II cytokine receptor family.

Protein type: Membrane protein, integral

Cellular Component: integral to membrane; plasma membrane

Molecular Function: interleukin-10 receptor activity; protein binding
 Il10rb ELISA Kit
 Il10rb Recombinant
 Il10rb Antibody
 Crfb4 ELISA Kit
 Crfb4 Recombinant
 Crfb4 Antibody
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