| Interleukin-11 receptor subunit alpha-1 ELISA Kit|
Interleukin-11 receptor subunit alpha-1 Recombinant
Interleukin-11 receptor subunit alpha-1 Antibody
|Also known as Interleukin-11 receptor subunit alpha-1 (IL-11 receptor subunit alpha-1) (IL-11R subunit alpha-1) (IL-11R-alpha-1) (IL-11RA1) (Enhancer trap locus homolog 2) (Etl-2) (Novel cytokine receptor 1) (NR-1) (NR1). |
IL11RA: Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth.
Restricts suture fusion and tooth number. Defects in IL11RA are a cause of craniosynostosis and dental anomalies (CRSDA). CRSDA is a disorder characterized by craniosynostosis, maxillary hypoplasia, and dental anomalies, including malocclusion, delayed and ectopic tooth eruption, and/or supernumerary teeth. Some patients also display minor digit anomalies, such as syndactyly and/or clinodactyly. Belongs to the type I cytokine receptor family. Type 3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Molecular Function: interleukin-11 binding; interleukin-11 receptor activity
Biological Process: cytokine and chemokine mediated signaling pathway; decidualization; maternal process involved in pregnancy; natural killer cell differentiation; placenta development; positive regulation of cell proliferation
| Il11ra1 ELISA Kit|
| Etl2 ELISA Kit|
| Il11ra ELISA Kit|