Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Protein Family  rightarrow Interleukin-31 receptor  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • interleukin 15 receptor, alpha (IL15RA) ELISA Kit
 • Ankyrin-1 (ANK1), partial Recombinant Protein
 • Rabbit Immunoglobulin Antibody
 • immunosuppressive acidic protein (IAP) ELISA Kit
 • Ovomucoid (OVM) ELISA Kit
 • OB-Cadherin - Cadherin-11 (CDH11) Antibody
 • Activin receptor type-2B (Acvr2b) Recombinant Protein
 • CA 242 Native Protein
 • Aquaporin-3 (Aqp3) Recombinant Protein
 • PI-3 KINASE p85 SUBUNIT ALPHA (PIK3R1) Antibody
 • Human Chorionic Gonadotropin (hCG), Free beta Antibody
 • Rabbit anti-Goat IgG Secondary Antibody
 • Clostridium difficile Toxin A Antibody
 downarrow more ...

Interleukin-31 receptor

Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 .

Below are the list of possible Interleukin-31 receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Interleukin-31 receptor subunit alpha

 Interleukin-31 receptor subunit alpha ELISA Kit
 Interleukin-31 receptor subunit alpha Recombinant
 Interleukin-31 receptor subunit alpha Antibody
Also known as Interleukin-31 receptor subunit alpha (IL-31 receptor subunit alpha) (IL-31R subunit alpha) (IL-31R-alpha) (IL-31RA) (Cytokine receptor-like 3) (GLM-R) (hGLM-R) (Gp130-like monocyte receptor) (Gp130-like receptor) (ZcytoR17).
IL31RA: Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Defects in IL31RA are the cause of amyloidosis primary localized cutaneous type 2 (PLCA2). PLCA2 is primary amyloidosis characterized by localized cutaneous amyloid deposition. This condition usually
presents with itching (especially on the lower legs) and visible changes of skin hyperpigmentation and thickening that may be exacerbated by chronic scratching and rubbing. Primary localized cutaneous amyloidosis is often divided into macular and lichen subtypes although many affected individuals often show both variants coexisting. Lichen amyloidosis characteristically presents as a pruritic eruption of grouped hyperkeratotic papules with a predilection for the shins, calves, ankles and dorsa of feet and thighs. Papules may coalesce to form hyperkeratotic plaques that can resemble lichen planus, lichen simplex or nodular prurigo. Macular amyloidosis is characterized by small pigmented macules that may merge to produce macular hyperpigmentation, sometimes with a reticulate or rippled pattern. In macular and lichen amyloidosis, amyloid is deposited in the papillary dermis in association with grouped colloid bodies, thought to represent degenerate basal keratinocytes. The amyloid deposits probably reflect a combination of degenerate keratin filaments, serum amyloid P component, and deposition of immunoglobulins. Belongs to the type I cytokine receptor family. Type 2 subfamily. 12 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: plasma membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity

Biological Process: cytokine and chemokine mediated signaling pathway; JAK-STAT cascade; monocyte differentiation; positive regulation of cell proliferation; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of tyrosine phosphorylation of Stat5 protein

Disease: Amyloidosis, Primary Localized Cutaneous, 2
 IL31RA Recombinant
 IL31RA Antibody
 CRL3 Recombinant
 CRL3 Antibody
 GPL Recombinant
 GPL Antibody
 UNQ6368/PRO21073/PRO21384 ELISA Kit
 UNQ6368/PRO21073/PRO21384 Recombinant
 UNQ6368/PRO21073/PRO21384 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions