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Interleukin-6 receptor

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Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.

Below are the list of possible Interleukin-6 receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Interleukin-6 receptor subunit alpha

 Interleukin-6 receptor subunit alpha ELISA Kit
 Interleukin-6 receptor subunit alpha Recombinant
 Interleukin-6 receptor subunit alpha Antibody
Also known as Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha) (IL-6R subunit alpha) (IL-6R-alpha) (IL-6RA) (IL-6R 1) (CD antigen CD126).
Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase react
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ions and hematopoiesis.
 IL6R ELISA Kit
 IL6R Recombinant
 IL6R Antibody
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Interleukin-6 receptor subunit beta

 Interleukin-6 receptor subunit beta ELISA Kit
 Interleukin-6 receptor subunit beta Recombinant
 Interleukin-6 receptor subunit beta Antibody
Also known as Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130).
gp130: gp130 is a ubiquitously expressed type I cytokine family receptor. The receptor systems for IL6, LIF, OSM, CNTF, IL11 AND CT1 utili
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ze gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not directly bind IL6. May have a role in embryonic development. Contains 5 fibronectin type III domains and 1 immunoglobulin-like C2-type domain. Two alternatively spliced isoforms have been described.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: extracellular region; interleukin-6 receptor complex; membrane; oncostatin-M receptor complex; plasma membrane

Molecular Function: ciliary neurotrophic factor receptor activity; ciliary neurotrophic factor receptor binding; growth factor binding; interleukin-27 receptor activity; interleukin-6 binding; interleukin-6 receptor activity; interleukin-6 receptor binding; leukemia inhibitory factor receptor activity; oncostatin-M receptor activity; protein binding; protein homodimerization activity

Biological Process: cytokine and chemokine mediated signaling pathway; leukemia inhibitory factor signaling pathway; negative regulation of apoptosis; positive regulation of acute inflammatory response; positive regulation of adaptive immune response; positive regulation of cell proliferation; positive regulation of osteoblast differentiation; positive regulation of T cell proliferation; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of tyrosine phosphorylation of Stat3 protein; response to cytokine stimulus
 IL6ST ELISA Kit
 IL6ST Recombinant
 IL6ST Antibody
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