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Intermediate conductance calcium-activated potassium channel protein

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Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.

Below are the list of possible Intermediate conductance calcium-activated potassium channel protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Intermediate conductance calcium-activated potassium channel protein 4

 Intermediate conductance calcium-activated potassium channel protein 4 ELISA Kit
 Intermediate conductance calcium-activated potassium channel protein 4 Recombinant
 Intermediate conductance calcium-activated potassium channel protein 4 Antibody
Also known as Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (SKCa 4) (SKCa4) (IK1) (KCa3.1) (KCa4).
KCNN4: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naiv
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e T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin. Belongs to the potassium channel KCNN family. KCa3.1/KCNN4 subfamily.

Protein type: Channel, potassium; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: apical plasma membrane; basolateral plasma membrane; cell soma; integral to plasma membrane; lipid raft; plasma membrane; vesicle

Molecular Function: calcium-activated potassium channel activity; Intermediate conductance calcium-activated potassium channel activity; potassium channel activity; protein phosphatase binding

Biological Process: anion transport; calcium ion transport; cell volume homeostasis; phospholipid translocation; positive regulation of protein secretion; positive regulation of T cell receptor signaling pathway; potassium ion transport; saliva secretion; stabilization of membrane potential
 Kcnn4 ELISA Kit
 Kcnn4 Recombinant
 Kcnn4 Antibody
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