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Invasin

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Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins.

Below are the list of possible Invasin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Invasin

 Invasin ELISA Kit
 Invasin Recombinant
 Invasin Antibody
Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins.
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Invasin IpaA

 Invasin IpaA ELISA Kit
 Invasin IpaA Recombinant
 Invasin IpaA Antibody
Also known as Invasin IpaA (70 kDa antigen).
Rapidly associates with the first 265 amino acids of vinculin after bacteria-cell contact. This interaction is critical for efficient Shigella uptake. IpaA acts as a potent activator of vinculin and increase its ability to interact with F-actin. The complex IpaA-vinculin induces F-actin depolymerization along with the occasional formation of actin fi
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lament bundles.
 ipaA ELISA Kit
 ipaA Recombinant
 ipaA Antibody
 CP0125 ELISA Kit
 CP0125 Recombinant
 CP0125 Antibody
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Invasin IpaB

 Invasin IpaB ELISA Kit
 Invasin IpaB Recombinant
 Invasin IpaB Antibody
Also known as Invasin IpaB (62 kDa antigen).
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Forms a pore with IpaC, which is inserted into the host cell membrane through the Mxi/Spa apparatus, during cell contact. This pore probably allows the translocation of IpaA. IpaB has also been found to be necessary and sufficient to activate macr
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ophage apoptosis by binding to interleukin-1 beta converting enzyme (ICE). Has also been shown to be important, along with IpaD, to block or regulate secretion through the Mxi/Spa translocon in the presence or absence of the secretion signal, respectively. Through interaction with host human MAD2L2, constitutively activates the anaphase-promoting complex APC and induces a cell cycle arrest to prevent epithelial renewal in order to promote bacterial colonization.
 ipaB ELISA Kit
 ipaB Recombinant
 ipaB Antibody
 CP0128 ELISA Kit
 CP0128 Recombinant
 CP0128 Antibody
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Invasin IpaC

 Invasin IpaC ELISA Kit
 Invasin IpaC Recombinant
 Invasin IpaC Antibody
Also known as Invasin IpaC (42 kDa antigen).
Associated with the entry of the bacteria into colonic epithelial cells.
 ipaC ELISA Kit
 ipaC Recombinant
 ipaC Antibody
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Invasin IpaD

 Invasin IpaD ELISA Kit
 Invasin IpaD Recombinant
 Invasin IpaD Antibody
Also known as Invasin IpaD (36 kDa membrane antigen).
Required for bacterial invasion of host cells. Controls IpaB and IpaC secretion, and the efficiency with which they are physically inserted into target cell membranes. These proteins are exported via TTSS to form a pore in the host membrane that allows the translocation of the other effectors into the host cytoplasm. Along with IpaB, is esse
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ntial for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling the level of secretion in the presence of this signal.
 ipaD ELISA Kit
 ipaD Recombinant
 ipaD Antibody
 CP0126 ELISA Kit
 CP0126 Recombinant
 CP0126 Antibody
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