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Iota-conotoxin

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Iota-conotoxins bind to voltage-gated sodium channels and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. This toxin enhances tetrodotoxin-sensitive sodium current in rat dorsal root ganglion neurons.

Below are the list of possible Iota-conotoxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Iota-conotoxin LtIIIA

 Iota-conotoxin LtIIIA ELISA Kit
 Iota-conotoxin LtIIIA Recombinant
 Iota-conotoxin LtIIIA Antibody
Also known as Iota-conotoxin LtIIIA (Lt3.1) (Lt3a).
Iota-conotoxins bind to voltage-gated sodium channels and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized
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levels. This toxin enhances tetrodotoxin-sensitive sodium current in rat dorsal root ganglion neurons.
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Iota-conotoxin RXIA

 Iota-conotoxin RXIA ELISA Kit
 Iota-conotoxin RXIA Recombinant
 Iota-conotoxin RXIA Antibody
Also known as Iota-conotoxin RXIA (R11.6) (r11a).
Iota-conotoxins bind to voltage-gated sodium channels and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized l
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evels. This toxin acts on Nav1.6/SCN8A > Nav1.2/SCN2A > Nav1.7/SCN9A sodium channels. Produces general excitatory symptoms upon intracorporeal injection and repetitive action potentials in the frog cutaneous pectoris muscle. Natural peptide (with D-Phe) is active on nerve, but not on muscle. Synthetic peptide (with L-Phe) is not active on both nerve and muscle.
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Iota-conotoxin-like Fi11.1

 Iota-conotoxin-like Fi11.1 ELISA Kit
 Iota-conotoxin-like Fi11.1 Recombinant
 Iota-conotoxin-like Fi11.1 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like Fi11.6

 Iota-conotoxin-like Fi11.6 ELISA Kit
 Iota-conotoxin-like Fi11.6 Recombinant
 Iota-conotoxin-like Fi11.6 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like Fi11.8

 Iota-conotoxin-like Fi11.8 ELISA Kit
 Iota-conotoxin-like Fi11.8 Recombinant
 Iota-conotoxin-like Fi11.8 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like L11.5

 Iota-conotoxin-like L11.5 ELISA Kit
 Iota-conotoxin-like L11.5 Recombinant
 Iota-conotoxin-like L11.5 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like M11.1

 Iota-conotoxin-like M11.1 ELISA Kit
 Iota-conotoxin-like M11.1 Recombinant
 Iota-conotoxin-like M11.1 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like M11.5

 Iota-conotoxin-like M11.5 ELISA Kit
 Iota-conotoxin-like M11.5 Recombinant
 Iota-conotoxin-like M11.5 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like R11.1

 Iota-conotoxin-like R11.1 ELISA Kit
 Iota-conotoxin-like R11.1 Recombinant
 Iota-conotoxin-like R11.1 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like R11.10

 Iota-conotoxin-like R11.10 ELISA Kit
 Iota-conotoxin-like R11.10 Recombinant
 Iota-conotoxin-like R11.10 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like R11.11

 Iota-conotoxin-like R11.11 ELISA Kit
 Iota-conotoxin-like R11.11 Recombinant
 Iota-conotoxin-like R11.11 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like R11.12

 Iota-conotoxin-like R11.12 ELISA Kit
 Iota-conotoxin-like R11.12 Recombinant
 Iota-conotoxin-like R11.12 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like R11.13

 Iota-conotoxin-like R11.13 ELISA Kit
 Iota-conotoxin-like R11.13 Recombinant
 Iota-conotoxin-like R11.13 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like R11.15

 Iota-conotoxin-like R11.15 ELISA Kit
 Iota-conotoxin-like R11.15 Recombinant
 Iota-conotoxin-like R11.15 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like R11.16

 Iota-conotoxin-like R11.16 ELISA Kit
 Iota-conotoxin-like R11.16 Recombinant
 Iota-conotoxin-like R11.16 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like R11.17

 Iota-conotoxin-like R11.17 ELISA Kit
 Iota-conotoxin-like R11.17 Recombinant
 Iota-conotoxin-like R11.17 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like R11.18

 Iota-conotoxin-like R11.18 ELISA Kit
 Iota-conotoxin-like R11.18 Recombinant
 Iota-conotoxin-like R11.18 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like R11.2

 Iota-conotoxin-like R11.2 ELISA Kit
 Iota-conotoxin-like R11.2 Recombinant
 Iota-conotoxin-like R11.2 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like R11.3

 Iota-conotoxin-like R11.3 ELISA Kit
 Iota-conotoxin-like R11.3 Recombinant
 Iota-conotoxin-like R11.3 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like R11.5

 Iota-conotoxin-like R11.5 ELISA Kit
 Iota-conotoxin-like R11.5 Recombinant
 Iota-conotoxin-like R11.5 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like R11.7

 Iota-conotoxin-like R11.7 ELISA Kit
 Iota-conotoxin-like R11.7 Recombinant
 Iota-conotoxin-like R11.7 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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Iota-conotoxin-like r11b

 Iota-conotoxin-like r11b ELISA Kit
 Iota-conotoxin-like r11b Recombinant
 Iota-conotoxin-like r11b Antibody
Also known as Iota-conotoxin-like r11b (I-superfamily conotoxin R11.14).
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activa
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tion to more hyperpolarized levels (). Produces excitatory symptoms when injected intracranially into mice and is lethal at higher doses. Exposure to frog cutaneous pectoris induces spontaneous and repetitive action potentials. This effect is slowly reversible. Natural peptide (with D-Phe) is active on nerve, but not on muscle. Synthetic peptide (with L-Phe) is not active on both nerve and muscle.
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Iota-conotoxin-like r11c

 Iota-conotoxin-like r11c ELISA Kit
 Iota-conotoxin-like r11c Recombinant
 Iota-conotoxin-like r11c Antibody
Also known as Iota-conotoxin-like r11c (R11.4).
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolariz
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ed levels (). Causes circular motion, convulsions, copious urination, rigid paralysis and death upon intracranial injection into mice. Causes unbalanced swimming, swimming in diagonal and vertical motion and death, when injected intraperitoneally into goldfish. L-Leu and D-Leu forms are active on both nerve and muscle.
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Iota-conotoxin-like r11d

 Iota-conotoxin-like r11d ELISA Kit
 Iota-conotoxin-like r11d Recombinant
 Iota-conotoxin-like r11d Antibody
Also known as Iota-conotoxin-like r11d (R11.8).
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolariz
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ed levels (). Both natural (L-Thr form) and synthetic (D-Thr form) peptides cause paralysis and death following intracranial injection and grooming and hypersensitivity upon intraperitoneal injection into mice. The L-Thr form of the peptide is 7-fold more potent than the D-Thr form. Both natural peptide (L-Thr form) and synthetic peptide (D-Thr form) are active on nerve, and on muscle.
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Iota-conotoxin-like S11.2

 Iota-conotoxin-like S11.2 ELISA Kit
 Iota-conotoxin-like S11.2 Recombinant
 Iota-conotoxin-like S11.2 Antibody
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels. Produces general excitatory symptoms ().
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