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IST1

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ESCRT-III-like protein involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing. Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST.

Below are the list of possible IST1 products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

IST1 homolog

 IST1 homolog ELISA Kit
 IST1 homolog Recombinant
 IST1 homolog Antibody
IST1: Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. Belongs to the IST1 family. 4 isoforms of the human protein are produced by alternative splicing.

Prot
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ein type: Cell cycle regulation; Vesicle

Cellular Component: centrosome; cytosol; ER-Golgi intermediate compartment; midbody

Molecular Function: protein complex binding; protein domain specific binding

Biological Process: abscission; cell division; establishment of protein localization; positive regulation of collateral sprouting; positive regulation of defense response to virus by host; positive regulation of proteolysis; protein localization; release of virus from host; viral capsid re-envelopment
 Ist1 ELISA Kit
 Ist1 Recombinant
 Ist1 Antibody
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