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Junctional adhesion molecule

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Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation.

Below are the list of possible Junctional adhesion molecule products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Junctional adhesion molecule A

 Junctional adhesion molecule A ELISA Kit
 Junctional adhesion molecule A Recombinant
 Junctional adhesion molecule A Antibody
Also known as Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD antigen CD321).
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in
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regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation.
 F11R ELISA Kit
 F11R Recombinant
 F11R Antibody
 JAM1 ELISA Kit
 JAM1 Recombinant
 JAM1 Antibody
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Junctional adhesion molecule B

 Junctional adhesion molecule B ELISA Kit
 Junctional adhesion molecule B Recombinant
 Junctional adhesion molecule B Antibody
Also known as Junctional adhesion molecule B (JAM-B) (Junctional adhesion molecule 2) (JAM-2) (Vascular endothelial junction-associated molecule) (VE-JAM) (CD antigen CD322).
JAM2: May play a role in the processes of lymphocyte homing to secondary lymphoid organs. Belongs to the immunoglobulin superfamily.

Protein type: Cell adhesion; Membrane protein, integral

Molecular Function:
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protein heterodimerization activity

Biological Process: negative regulation of cell adhesion
 Jam2 ELISA Kit
 Jam2 Recombinant
 Jam2 Antibody
 Vejam ELISA Kit
 Vejam Recombinant
 Vejam Antibody
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Junctional adhesion molecule C

 Junctional adhesion molecule C ELISA Kit
 Junctional adhesion molecule C Recombinant
 Junctional adhesion molecule C Antibody
Also known as Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3).
JAM3: Participates in cell-cell adhesion. It is a counter- receptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN). The soluble form is a mediator of angiogenesis. Defects in JAM3 are th
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e cause of hemorrhagic destruction of the brain with subependymal calcification and cataracts (HDBSCC). A syndrome characterized by congenital cataracts and severe brain abnormalities apparently resulting from hemorrhagic destruction of the brain tissue, including the cerebral white matter and basal ganglia. Patients manifest profound developmental delay, and other neurologic features included seizures, spasticity, and hyperreflexia. Brain imaging shows multifocal intraparenchymal hemorrhage with associated liquefaction and massive cystic degeneration, and calcification in the subependymal region and in brain tissue. Belongs to the immunoglobulin superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q25

Cellular Component: desmosome; extracellular space; Golgi apparatus; plasma membrane

Molecular Function: integrin binding; protein binding

Biological Process: angiogenesis; extracellular matrix organization and biogenesis; leukocyte migration

Disease: Hemorrhagic Destruction Of The Brain, Subependymal Calcification, And Cataracts
 JAM3 ELISA Kit
 JAM3 Recombinant
 JAM3 Antibody
 UNQ859/PRO1868 ELISA Kit
 UNQ859/PRO1868 Recombinant
 UNQ859/PRO1868 Antibody
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Junctional adhesion molecule-like

 Junctional adhesion molecule-like ELISA Kit
 Junctional adhesion molecule-like Recombinant
 Junctional adhesion molecule-like Antibody
Also known as Junctional adhesion molecule-like (Adhesion molecule interacting with CXADR antigen 1) (Dendritic cell-specific protein CREA7-1).
AMICA1: an adhesion molecule that may function in the migration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells. Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells.
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Three alternatively spliced isoforms have been described.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: plasma membrane; tight junction

Molecular Function: cell adhesion molecule binding; integrin binding; protein homodimerization activity

Biological Process: gamma-delta T cell activation; heterophilic cell adhesion; leukocyte migration; neutrophil chemotaxis; positive regulation of epithelial cell proliferation involved in wound healing; regulation of immune response
 JAML ELISA Kit
 JAML Recombinant
 JAML Antibody
 AMICA1 ELISA Kit
 AMICA1 Recombinant
 AMICA1 Antibody
 UNQ722/PRO1387 ELISA Kit
 UNQ722/PRO1387 Recombinant
 UNQ722/PRO1387 Antibody
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Proteins Root Name Listing
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