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Kelch-like protein

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May play a role in organizing the actin cytoskeleton of the brain cells.

Below are the list of possible Kelch-like protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Kelch-like protein 1

 Kelch-like protein 1 ELISA Kit
 Kelch-like protein 1 Recombinant
 Kelch-like protein 1 Antibody
KLHL1: May play a role in organizing the actin cytoskeleton of the brain cells.

Chromosomal Location of Human Ortholog: 13q21

Cellular Component: cell soma; cytoplasm; dendrite

Molecular Function: ubiquitin-protein ligase activity

Biological Process: dendrite development
 KLHL1 ELISA Kit
 KLHL1 Recombinant
 KLHL1 Antibody
 KIAA1490 ELISA Kit
 KIAA1490 Recombinant
 KIAA1490 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 10

 Kelch-like protein 10 ELISA Kit
 Kelch-like protein 10 Recombinant
 Kelch-like protein 10 Antibody
KLHL10: Self-associates (Probable). Interacts with CUL3

Cellular Component: cytoplasm

Molecular Function: protein binding; ubiquitin-protein ligase activity

Biological Process: cell morphogenesis; fertilization; homeostasis of number of cells within a tissue; male genitalia morphogenesis; male gonad development; spermatid development
 Klhl10 ELISA Kit
 Klhl10 Recombinant
 Klhl10 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 11

 Kelch-like protein 11 ELISA Kit
 Kelch-like protein 11 Recombinant
 Kelch-like protein 11 Antibody
KLHL11: Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. Homodimer. Interacts with CUL3

Protein type: Secreted; Secreted, signal peptide

Cellular Comp
>>>
onent: cytoplasm; SCF ubiquitin ligase complex

Molecular Function: ubiquitin protein ligase binding

Biological Process: proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination during ubiquitin-dependent protein catabolic process; regulation of proteolysis
 Klhl11 ELISA Kit
 Klhl11 Recombinant
 Klhl11 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 12

 Kelch-like protein 12 ELISA Kit
 Kelch-like protein 12 Recombinant
 Kelch-like protein 12 Antibody
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division (). Negatively regulates the Wnt signaling pathway, possibly via the targeted ubiquitination and subsequent proteolysis of dvl2 and dvl3. Regulates convergent-extension movements during early embryonic development.
 klhl12 ELISA Kit
 klhl12 Recombinant
 klhl12 Antibody
 si:dkeyp-53e12.5 ELISA Kit
 si:dkeyp-53e12.5 Recombinant
 si:dkeyp-53e12.5 Antibody
 zgc:92570 ELISA Kit
 zgc:92570 Recombinant
 zgc:92570 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 13

 Kelch-like protein 13 ELISA Kit
 Kelch-like protein 13 Recombinant
 Kelch-like protein 13 Antibody
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis ().
 KLHL13 ELISA Kit
 KLHL13 Recombinant
 KLHL13 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 14

 Kelch-like protein 14 ELISA Kit
 Kelch-like protein 14 Recombinant
 Kelch-like protein 14 Antibody
 KLHL14 ELISA Kit
 KLHL14 Recombinant
 KLHL14 Antibody
 RCJMB04_11g14 ELISA Kit
 RCJMB04_11g14 Recombinant
 RCJMB04_11g14 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 15

 Kelch-like protein 15 ELISA Kit
 Kelch-like protein 15 Recombinant
 Kelch-like protein 15 Antibody
KLHL15: a substrate-specific adapter for the recruitment of substrates to Cul3-based E3 ubiquitin ligases. KLHL15-Cul3 specifically targets the PP2A regulatory subunit PPP2R5B to promote its turnover by ubiquitylation and proteasomal degradation. May contribute to the selective expression of the PP2A/B holoenzyme in the brain.

Protein type: Ubiquitin conjugating system

Chromosomal Lo
>>>
cation of Human Ortholog: Xp22.1-p21

Cellular Component: nucleus

Molecular Function: protein binding; ubiquitin-protein ligase activity

Biological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process

Disease: Mental Retardation, X-linked 103
 KLHL15 ELISA Kit
 KLHL15 Recombinant
 KLHL15 Antibody
 KIAA1677 ELISA Kit
 KIAA1677 Recombinant
 KIAA1677 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 17

 Kelch-like protein 17 ELISA Kit
 Kelch-like protein 17 Recombinant
 Kelch-like protein 17 Antibody
Also known as Kelch-like protein 17 (Actinfilin).
Actinfilin: Substrate-recognition component of some cullin-RING- based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(KLHL17) mediates the ubiquitination and subsequenct degradation of GLUR6. May play a role in the actin-based neuronal function.

Protein type: Actin-binding; Ubiquitin conjugating system

Chromosomal
>>>
Location of Human Ortholog: 1p36.33

Cellular Component: actin cytoskeleton; dendrite cytoplasm; extracellular space

Molecular Function: actin filament binding; protein complex scaffold; ubiquitin-protein ligase activity

Biological Process: actin cytoskeleton organization and biogenesis; brain development
 KLHL17 ELISA Kit
 KLHL17 Recombinant
 KLHL17 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 18

 Kelch-like protein 18 ELISA Kit
 Kelch-like protein 18 Recombinant
 Kelch-like protein 18 Antibody
KLHL18: 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 3p21.31

Molecular Function: protein binding; ubiquitin-protein ligase activity
 KLHL18 ELISA Kit
 KLHL18 Recombinant
 KLHL18 Antibody
 KIAA0795 ELISA Kit
 KIAA0795 Recombinant
 KIAA0795 Antibody
 OK/SW-cl.74 ELISA Kit
 OK/SW-cl.74 Recombinant
 OK/SW-cl.74 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 2

 Kelch-like protein 2 ELISA Kit
 Kelch-like protein 2 Recombinant
 Kelch-like protein 2 Antibody
KLHL2: May play a role in organizing the actin cytoskeleton of the brain cells. 2 isoforms of the human protein are produced by alternative splicing.

Cellular Component: actin cytoskeleton; cytoplasm; stress fiber

Molecular Function: actin binding; protein homodimerization activity; ubiquitin-protein ligase activity

Biological Process: protein ubiquitination
 Klhl2 ELISA Kit
 Klhl2 Recombinant
 Klhl2 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 20

 Kelch-like protein 20 ELISA Kit
 Kelch-like protein 20 Recombinant
 Kelch-like protein 20 Antibody
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response and anterograde Golgi to endosome transport. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome. It also specifically mediates 'Lys-33'-linked ubiquitination ().
 klhl20 ELISA Kit
 klhl20 Recombinant
 klhl20 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 21

 Kelch-like protein 21 ELISA Kit
 Kelch-like protein 21 Recombinant
 Kelch-like protein 21 Antibody
Substrate-specific adapter of BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquit
>>>
in ligase complex may not lead to its degradation by the proteasome ().
 Klhl21 ELISA Kit
 Klhl21 Recombinant
 Klhl21 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 22

 Kelch-like protein 22 ELISA Kit
 Kelch-like protein 22 Recombinant
 Kelch-like protein 22 Antibody
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores.
 klhl22 ELISA Kit
 klhl22 Recombinant
 klhl22 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 23

 Kelch-like protein 23 ELISA Kit
 Kelch-like protein 23 Recombinant
 Kelch-like protein 23 Antibody
KLHL23:

Chromosomal Location of Human Ortholog: 2q31.1

Molecular Function: protein binding; ubiquitin-protein ligase activity
 KLHL23 ELISA Kit
 KLHL23 Recombinant
 KLHL23 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 24

 Kelch-like protein 24 ELISA Kit
 Kelch-like protein 24 Recombinant
 Kelch-like protein 24 Antibody
Also known as Kelch-like protein 24 (Kainate receptor-interacting protein for GluR6) (KRIP6).
KLHL24: Specifically reduces kainate receptor-mediated currents in hippocampal neurons, most probably by modulating channel properties. 2 isoforms of the human protein are produced by alternative splicing.

Molecular Function: ubiquitin-protein ligase activity
 Klhl24 ELISA Kit
 Klhl24 Recombinant
 Klhl24 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 25

 Kelch-like protein 25 ELISA Kit
 Kelch-like protein 25 Recombinant
 Kelch-like protein 25 Antibody
Also known as Kelch-like protein 25 (Ectoderm-neural cortex protein 2) (ENC-2).
KLHL25: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (
>>>
4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E. Component of the BCR(KLHL25) E3 ubiquitin ligase complex, at least composed of CUL3, KLHL25 and RBX1. Interacts with EIF4EBP1 (when hypophosphorylated)

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 15q25.3

Cellular Component: cytoplasm

Biological Process: protein ubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process; regulation of translational initiation
 KLHL25 ELISA Kit
 KLHL25 Recombinant
 KLHL25 Antibody
 ENC2 ELISA Kit
 ENC2 Recombinant
 ENC2 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 26

 Kelch-like protein 26 ELISA Kit
 Kelch-like protein 26 Recombinant
 Kelch-like protein 26 Antibody
 klhl26 ELISA Kit
 klhl26 Recombinant
 klhl26 Antibody
 si:ch211-255d18.7 ELISA Kit
 si:ch211-255d18.7 Recombinant
 si:ch211-255d18.7 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 28

 Kelch-like protein 28 ELISA Kit
 Kelch-like protein 28 Recombinant
 Kelch-like protein 28 Antibody
Also known as Kelch-like protein 28 (BTB/POZ domain-containing protein 5).
KLHL28: 2 isoforms of the human protein are produced by alternative splicing.

Molecular Function: ubiquitin-protein ligase activity

Biological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process
 Klhl28 ELISA Kit
 Klhl28 Recombinant
 Klhl28 Antibody
 Btbd5 ELISA Kit
 Btbd5 Recombinant
 Btbd5 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 29

 Kelch-like protein 29 ELISA Kit
 Kelch-like protein 29 Recombinant
 Kelch-like protein 29 Antibody
Also known as Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9).
KLHL29: 2 isoforms of the human protein are produced by alternative splicing

Molecular Function: ubiquitin-protein ligase activity
 Klhl29 ELISA Kit
 Klhl29 Recombinant
 Klhl29 Antibody
 Kbtbd9 ELISA Kit
 Kbtbd9 Recombinant
 Kbtbd9 Antibody
 Kiaa1921 ELISA Kit
 Kiaa1921 Recombinant
 Kiaa1921 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 3

 Kelch-like protein 3 ELISA Kit
 Kelch-like protein 3 Recombinant
 Kelch-like protein 3 Antibody
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron.
 klhl3 ELISA Kit
 klhl3 Recombinant
 klhl3 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 30

 Kelch-like protein 30 ELISA Kit
 Kelch-like protein 30 Recombinant
 Kelch-like protein 30 Antibody
 klhl30 ELISA Kit
 klhl30 Recombinant
 klhl30 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 31

 Kelch-like protein 31 ELISA Kit
 Kelch-like protein 31 Recombinant
 Kelch-like protein 31 Antibody
Also known as Kelch-like protein 31 (BTB and kelch domain-containing protein 6) (Kelch repeat and BTB domain-containing protein 1) (Kelch-like protein KLHL).
KLHL31: Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE).

Chromosomal Location of Human Ortholog: 6p12.1

Molecular Function: ubiquitin-protein ligase activity
 KLHL31 ELISA Kit
 KLHL31 Recombinant
 KLHL31 Antibody
 BKLHD6 ELISA Kit
 BKLHD6 Recombinant
 BKLHD6 Antibody
 KBTBD1 ELISA Kit
 KBTBD1 Recombinant
 KBTBD1 Antibody
 KLHL ELISA Kit
 KLHL Recombinant
 KLHL Antibody
Table BarTOPTable Bar
 

Kelch-like protein 32

 Kelch-like protein 32 ELISA Kit
 Kelch-like protein 32 Recombinant
 Kelch-like protein 32 Antibody
Also known as Kelch-like protein 32 (BTB and kelch domain-containing protein 5).
KLHL32: 3 isoforms of the human protein are produced by alternative splicing

Chromosomal Location of Human Ortholog: 6q16.1

Molecular Function: ubiquitin-protein ligase activity

Biological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process
 KLHL32 ELISA Kit
 KLHL32 Recombinant
 KLHL32 Antibody
 BKLHD5 ELISA Kit
 BKLHD5 Recombinant
 BKLHD5 Antibody
 KIAA1900 ELISA Kit
 KIAA1900 Recombinant
 KIAA1900 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 33

 Kelch-like protein 33 ELISA Kit
 Kelch-like protein 33 Recombinant
 Kelch-like protein 33 Antibody
KLHL33:

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: actin cytoskeleton

Molecular Function: actin binding; ubiquitin-protein ligase activity
 KLHL33 ELISA Kit
 KLHL33 Recombinant
 KLHL33 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 34

 Kelch-like protein 34 ELISA Kit
 Kelch-like protein 34 Recombinant
 Kelch-like protein 34 Antibody
KLHL34:

Chromosomal Location of Human Ortholog: Xp22.12

Cellular Component: extracellular space

Molecular Function: ubiquitin-protein ligase activity
 KLHL34 ELISA Kit
 KLHL34 Recombinant
 KLHL34 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 35

 Kelch-like protein 35 ELISA Kit
 Kelch-like protein 35 Recombinant
 Kelch-like protein 35 Antibody
KLHL35: 2 isoforms of the human protein are produced by alternative splicing.

Molecular Function: ubiquitin-protein ligase activity
 Klhl35 ELISA Kit
 Klhl35 Recombinant
 Klhl35 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 36

 Kelch-like protein 36 ELISA Kit
 Kelch-like protein 36 Recombinant
 Kelch-like protein 36 Antibody
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
 KLHL36 ELISA Kit
 KLHL36 Recombinant
 KLHL36 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 38

 Kelch-like protein 38 ELISA Kit
 Kelch-like protein 38 Recombinant
 Kelch-like protein 38 Antibody
 klhl38 ELISA Kit
 klhl38 Recombinant
 klhl38 Antibody
 si:dkey-5e12.1 ELISA Kit
 si:dkey-5e12.1 Recombinant
 si:dkey-5e12.1 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 4

 Kelch-like protein 4 ELISA Kit
 Kelch-like protein 4 Recombinant
 Kelch-like protein 4 Antibody
KLHL4: 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: Xq21.3

Cellular Component: cytoplasm

Molecular Function: ubiquitin-protein ligase activity
 KLHL4 ELISA Kit
 KLHL4 Recombinant
 KLHL4 Antibody
 KIAA1687 ELISA Kit
 KIAA1687 Recombinant
 KIAA1687 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 40

 Kelch-like protein 40 ELISA Kit
 Kelch-like protein 40 Recombinant
 Kelch-like protein 40 Antibody
Also known as Kelch-like protein 40 (Kelch repeat and BTB domain-containing protein 5).
Required for skeletal muscle development.
 klhl40 ELISA Kit
 klhl40 Recombinant
 klhl40 Antibody
 kbtbd5 ELISA Kit
 kbtbd5 Recombinant
 kbtbd5 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 40a

 Kelch-like protein 40a ELISA Kit
 Kelch-like protein 40a Recombinant
 Kelch-like protein 40a Antibody
Also known as Kelch-like protein 40a (Kelch repeat and BTB domain-containing protein 5a).
Required for skeletal muscle development.
 klhl40a ELISA Kit
 klhl40a Recombinant
 klhl40a Antibody
 kbtbd5a ELISA Kit
 kbtbd5a Recombinant
 kbtbd5a Antibody
Table BarTOPTable Bar
 

Kelch-like protein 40b

 Kelch-like protein 40b ELISA Kit
 Kelch-like protein 40b Recombinant
 Kelch-like protein 40b Antibody
Also known as Kelch-like protein 40b (Kelch repeat and BTB domain-containing protein 5b).
Required for skeletal muscle development.
 klhl40b ELISA Kit
 klhl40b Recombinant
 klhl40b Antibody
 kbtbd5b ELISA Kit
 kbtbd5b Recombinant
 kbtbd5b Antibody
Table BarTOPTable Bar
 

Kelch-like protein 41

 Kelch-like protein 41 ELISA Kit
 Kelch-like protein 41 Recombinant
 Kelch-like protein 41 Antibody
Also known as Kelch-like protein 41 (Kelch repeat and BTB domain-containing protein 10).
KBTBD10: Required for pseudopod elongation in transformed cells. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. 2 isoforms of the human protein are produced by alternative splicing.

Prot
>>>
ein type: Cell adhesion; Contractile; Cytoskeletal; Ubiquitin conjugating system

Cellular Component: cytoplasm; cytoskeleton; endoplasmic reticulum membrane; M band; nucleus; plasma membrane; pseudopodium; sarcoplasmic reticulum membrane

Molecular Function: ubiquitin-protein ligase activity

Biological Process: myofibril assembly; protein ubiquitination; regulation of lateral pseudopodium formation; regulation of myoblast differentiation; sarcomere organization; skeletal muscle fiber development
 Klhl41 ELISA Kit
 Klhl41 Recombinant
 Klhl41 Antibody
 Kbtbd10 ELISA Kit
 Kbtbd10 Recombinant
 Kbtbd10 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 41a

 Kelch-like protein 41a ELISA Kit
 Kelch-like protein 41a Recombinant
 Kelch-like protein 41a Antibody
Also known as Kelch-like protein 41a (Kelch repeat and BTB domain-containing protein 10b).
Involved in skeletal muscle development and differentiation.
 klhl41a ELISA Kit
 klhl41a Recombinant
 klhl41a Antibody
 kbtbd10a ELISA Kit
 kbtbd10a Recombinant
 kbtbd10a Antibody
Table BarTOPTable Bar
 

Kelch-like protein 41b

 Kelch-like protein 41b ELISA Kit
 Kelch-like protein 41b Recombinant
 Kelch-like protein 41b Antibody
Also known as Kelch-like protein 41b (Kelch repeat and BTB domain-containing protein 10b).
Involved in skeletal muscle development and maintenance.
 klhl41b ELISA Kit
 klhl41b Recombinant
 klhl41b Antibody
 kbtbd10b ELISA Kit
 kbtbd10b Recombinant
 kbtbd10b Antibody
Table BarTOPTable Bar
 

Kelch-like protein 42

 Kelch-like protein 42 ELISA Kit
 Kelch-like protein 42 Recombinant
 Kelch-like protein 42 Antibody
Also known as Kelch-like protein 42 (Cullin-3-binding protein 9) (Ctb9) (Kelch domain-containing protein 5).
KLHDC5: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis. Up-regulated during mitosis. Component of the BCR(KLHL42) E3 ubiquitin ligase complex, at least composed of CUL3 and KLHL42. Interacts (via the BTB domain) with CUL3. Interacts (v
>>>
ia the kelch domains) with KATNA1

Protein type: Unknown function

Molecular Function: ubiquitin-protein ligase activity

Biological Process: proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; regulation of microtubule-based process
 Klhl42 ELISA Kit
 Klhl42 Recombinant
 Klhl42 Antibody
 Kiaa1340 ELISA Kit
 Kiaa1340 Recombinant
 Kiaa1340 Antibody
 Klhdc5 ELISA Kit
 Klhdc5 Recombinant
 Klhdc5 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 5

 Kelch-like protein 5 ELISA Kit
 Kelch-like protein 5 Recombinant
 Kelch-like protein 5 Antibody
KLHL5: 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 4p14

Molecular Function: ubiquitin-protein ligase activity
 KLHL5 ELISA Kit
 KLHL5 Recombinant
 KLHL5 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 6

 Kelch-like protein 6 ELISA Kit
 Kelch-like protein 6 Recombinant
 Kelch-like protein 6 Antibody
KLHL6: Involved in B-lymphocyte antigen receptor signaling and germinal center formation.

Chromosomal Location of Human Ortholog: 3q27.3

Molecular Function: protein binding
 KLHL6 ELISA Kit
 KLHL6 Recombinant
 KLHL6 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 7

 Kelch-like protein 7 ELISA Kit
 Kelch-like protein 7 Recombinant
 Kelch-like protein 7 Antibody
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination ().
 KLHL7 ELISA Kit
 KLHL7 Recombinant
 KLHL7 Antibody
 RCJMB04_30p4 ELISA Kit
 RCJMB04_30p4 Recombinant
 RCJMB04_30p4 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 8

 Kelch-like protein 8 ELISA Kit
 Kelch-like protein 8 Recombinant
 Kelch-like protein 8 Antibody
KLHL8: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN. Component of the BCR(KLHL8) E3 ubiquitin ligase complex, at least composed of CUL3, KLHL8 and RBX1. Interacts with RAPSN

Chromosomal Location of Human Ortholog: 4q22.1

Cellular Component: nucleopl
>>>
asm

Molecular Function: ubiquitin-protein ligase activity

Biological Process: protein ubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process
 KLHL8 ELISA Kit
 KLHL8 Recombinant
 KLHL8 Antibody
 KIAA1378 ELISA Kit
 KIAA1378 Recombinant
 KIAA1378 Antibody
Table BarTOPTable Bar
 

Kelch-like protein 9

 Kelch-like protein 9 ELISA Kit
 Kelch-like protein 9 Recombinant
 Kelch-like protein 9 Antibody
KLHL9: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.

Protein typ
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e: Adaptor/scaffold; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 9p22

Cellular Component: midbody

Molecular Function: ubiquitin-protein ligase activity

Biological Process: cytokinesis; protein ubiquitination
 KLHL9 ELISA Kit
 KLHL9 Recombinant
 KLHL9 Antibody
 KIAA1354 ELISA Kit
 KIAA1354 Recombinant
 KIAA1354 Antibody
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Kelch-like protein terF

 Kelch-like protein terF ELISA Kit
 Kelch-like protein terF Recombinant
 Kelch-like protein terF Antibody
Also known as Kelch-like protein terF (Terrein biosynthesis cluster protein terF).
Kelch-like protein; part of the gene cluster that mediates the biosynthesis of terrein, a fungal metabolite with ecological, antimicrobial, antiproliferative, and antioxidative activities (PubMed:24816227). The first step in the pathway is performed by the polyketide synthase terA that produces 4-hydroxy-6-methyl
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pyranon (4-HMP), orsellinic acid (OA), and 2,3-dehydro-6-hydroxymellein (2,3-dehydro-6-HM) by condensing acetyl-CoA with two, three, or four malonyl-CoA units, respectively (PubMed:24816227). 4-HMP and OA are not pathway intermediates, but are rather shunt or side products (PubMed:24816227). 2,3-dehydro-6-HM is further converted to 6-hydroxymellein (6-HM) by the 6-hydroxymellein synthase terB (PubMed:24816227). The monooxygenases terC and terD, the multicopper oxidase terE and the Kelch-like protein terF are then involved in the transformation of 6-HM to terrein (PubMed:24816227). Even if they are co-regulated with the other terrein cluster genes, terH and terI seem to be dispensable for terrein production; whereas one or both of the 2 transporters terG and terJ are probably required for efficient secretion of metabolites (PubMed:24816227).
 terF ELISA Kit
 terF Recombinant
 terF Antibody
 ATEG_00140 ELISA Kit
 ATEG_00140 Recombinant
 ATEG_00140 Antibody
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Proteins Root Name Listing
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