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Killer cell lectin-like receptor subfamily

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Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells.

Below are the list of possible Killer cell lectin-like receptor subfamily products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Killer cell lectin-like receptor subfamily B member 1

 Killer cell lectin-like receptor subfamily B member 1 ELISA Kit
 Killer cell lectin-like receptor subfamily B member 1 Recombinant
 Killer cell lectin-like receptor subfamily B member 1 Antibody
Also known as Killer cell lectin-like receptor subfamily B member 1 (C-type lectin domain family 5 member B) (HNKR-P1a) (NKR-P1A) (Natural killer cell surface protein P1A) (CD antigen CD161).
KLRB1: Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate
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Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: plasma membrane

Molecular Function: transmembrane receptor activity

Biological Process: cell surface receptor linked signal transduction; regulation of immune response
 KLRB1 ELISA Kit
 KLRB1 Recombinant
 KLRB1 Antibody
 CLEC5B ELISA Kit
 CLEC5B Recombinant
 CLEC5B Antibody
 NKRP1A ELISA Kit
 NKRP1A Recombinant
 NKRP1A Antibody
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Killer cell lectin-like receptor subfamily B member 1A

 Killer cell lectin-like receptor subfamily B member 1A ELISA Kit
 Killer cell lectin-like receptor subfamily B member 1A Recombinant
 Killer cell lectin-like receptor subfamily B member 1A Antibody
Also known as Killer cell lectin-like receptor subfamily B member 1A (NKR-P1A) (Antigen 3.2.3) (CD161 antigen-like family member A) (Natural killer cell surface protein P1-3.2.3) (NKR-P1 3.2.3) (CD antigen CD161a).
Plays a stimulatory role on natural killer (NK) cell cytotoxicity.
 Klrb1a ELISA Kit
 Klrb1a Recombinant
 Klrb1a Antibody
 Nkrp1a ELISA Kit
 Nkrp1a Recombinant
 Nkrp1a Antibody
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Killer cell lectin-like receptor subfamily B member 1B allele A

 Killer cell lectin-like receptor subfamily B member 1B allele A ELISA Kit
 Killer cell lectin-like receptor subfamily B member 1B allele A Recombinant
 Killer cell lectin-like receptor subfamily B member 1B allele A Antibody
Also known as Killer cell lectin-like receptor subfamily B member 1B allele A (CD161 antigen-like family member B) (Lymphocyte antigen 55b) (Ly-55b) (NKR-P1 34) (Natural killer cell surface protein NKR-P1B allele SJL/BALB) (NKR-P1B) (CD antigen CD161b).
Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent "missing-self" recognition of allografts, tumor cells and virus-infected cells.
 Klrb1b ELISA Kit
 Klrb1b Recombinant
 Klrb1b Antibody
 Ly55b ELISA Kit
 Ly55b Recombinant
 Ly55b Antibody
 Nkrp1b ELISA Kit
 Nkrp1b Recombinant
 Nkrp1b Antibody
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Killer cell lectin-like receptor subfamily B member 1B allele B

 Killer cell lectin-like receptor subfamily B member 1B allele B ELISA Kit
 Killer cell lectin-like receptor subfamily B member 1B allele B Recombinant
 Killer cell lectin-like receptor subfamily B member 1B allele B Antibody
Also known as Killer cell lectin-like receptor subfamily B member 1B allele B (CD161 antigen-like family member B) (Immunoreceptor NKR-P1C) (Natural killer cell surface protein NKR-P1B allele WAG/PVG/BS) (Natural killer lymphocyte receptor P1B) (CD antigen CD161b).
Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells.
 Klrb1b ELISA Kit
 Klrb1b Recombinant
 Klrb1b Antibody
 Nkrp1b ELISA Kit
 Nkrp1b Recombinant
 Nkrp1b Antibody
 Nkrp1c ELISA Kit
 Nkrp1c Recombinant
 Nkrp1c Antibody
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Killer cell lectin-like receptor subfamily B member 1B allele C

 Killer cell lectin-like receptor subfamily B member 1B allele C ELISA Kit
 Killer cell lectin-like receptor subfamily B member 1B allele C Recombinant
 Killer cell lectin-like receptor subfamily B member 1B allele C Antibody
Also known as Killer cell lectin-like receptor subfamily B member 1B allele C (CD161 antigen-like family member B) (Natural killer cell surface protein NKR-P1B allele TO) (CD antigen CD161b).
signal transduction molecule [RGD, Feb 2006]
 Klrb1b ELISA Kit
 Klrb1b Recombinant
 Klrb1b Antibody
 Nkrp1b ELISA Kit
 Nkrp1b Recombinant
 Nkrp1b Antibody
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Killer cell lectin-like receptor subfamily B member 1C

 Killer cell lectin-like receptor subfamily B member 1C ELISA Kit
 Killer cell lectin-like receptor subfamily B member 1C Recombinant
 Killer cell lectin-like receptor subfamily B member 1C Antibody
Also known as Killer cell lectin-like receptor subfamily B member 1C (CD161 antigen-like family member C) (Lymphocyte antigen 55c) (Ly-55c) (NK1.1) (NKR-P1.9) (NKR-P1C) (Natural killer cell surface protein P1-40) (NKR-P1 40) (CD antigen CD161c).
KLRB1C: Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production. Contains 1 C-type lectin domain.

Cellular Component: external side of plasma membrane; integral to plasma membrane; plasma membrane

Molecular Function: prot
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ein homodimerization activity; receptor activity

Biological Process: natural killer cell activation; positive regulation of natural killer cell mediated cytotoxicity
 Klrb1c ELISA Kit
 Klrb1c Recombinant
 Klrb1c Antibody
 Ly55c ELISA Kit
 Ly55c Recombinant
 Ly55c Antibody
 Nkrp1c ELISA Kit
 Nkrp1c Recombinant
 Nkrp1c Antibody
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Killer cell lectin-like receptor subfamily B member 1F

 Killer cell lectin-like receptor subfamily B member 1F ELISA Kit
 Killer cell lectin-like receptor subfamily B member 1F Recombinant
 Killer cell lectin-like receptor subfamily B member 1F Antibody
Also known as Killer cell lectin-like receptor subfamily B member 1F (CD161 antigen-like family member F) (Natural killer cell surface protein NKR-P1F) (CD antigen CD161f).
Binds CLEC2I/Clr-g leading to activation of natural killer cells or costimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synap
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se between T-cells and antigen-presenting dendritic cells.
 Klrb1f ELISA Kit
 Klrb1f Recombinant
 Klrb1f Antibody
 Nkrp1f ELISA Kit
 Nkrp1f Recombinant
 Nkrp1f Antibody
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Killer cell lectin-like receptor subfamily F member 1

 Killer cell lectin-like receptor subfamily F member 1 ELISA Kit
 Killer cell lectin-like receptor subfamily F member 1 Recombinant
 Killer cell lectin-like receptor subfamily F member 1 Antibody
Also known as Killer cell lectin-like receptor subfamily F member 1 (Lectin-like receptor F1) (Activating coreceptor NKp80).
Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.
 KLRF1 ELISA Kit
 KLRF1 Recombinant
 KLRF1 Antibody
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Killer cell lectin-like receptor subfamily F member 2

 Killer cell lectin-like receptor subfamily F member 2 ELISA Kit
 Killer cell lectin-like receptor subfamily F member 2 Recombinant
 Killer cell lectin-like receptor subfamily F member 2 Antibody
Also known as Killer cell lectin-like receptor subfamily F member 2 (Lectin-like receptor F2) (Activating coreceptor NKp65).
KLRF2: C-type lectin-like receptor involved in natural killer cell mediated cytotoxicity and cytokine secretion in keratinocytes via its interaction with CLEC2A.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13

Ce
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llular Component: integral to plasma membrane

Molecular Function: protein binding; protein homodimerization activity

Biological Process: cytokine secretion; natural killer cell degranulation
 KLRF2 ELISA Kit
 KLRF2 Recombinant
 KLRF2 Antibody
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Killer cell lectin-like receptor subfamily G member 1

 Killer cell lectin-like receptor subfamily G member 1 ELISA Kit
 Killer cell lectin-like receptor subfamily G member 1 Recombinant
 Killer cell lectin-like receptor subfamily G member 1 Antibody
Also known as Killer cell lectin-like receptor subfamily G member 1 (C-type lectin domain family 15 member A) (ITIM-containing receptor MAFA-L) (MAFA-like receptor) (Mast cell function-associated antigen).
KLRG1: Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. 2 isoforms of the human protein are produced by alternative spli
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cing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.31

Molecular Function: protein binding; receptor activity

Biological Process: cell surface receptor linked signal transduction; cellular defense response; inflammatory response
 KLRG1 ELISA Kit
 KLRG1 Recombinant
 KLRG1 Antibody
 CLEC15A ELISA Kit
 CLEC15A Recombinant
 CLEC15A Antibody
 MAFA ELISA Kit
 MAFA Recombinant
 MAFA Antibody
 MAFAL ELISA Kit
 MAFAL Recombinant
 MAFAL Antibody
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Killer cell lectin-like receptor subfamily G member 2

 Killer cell lectin-like receptor subfamily G member 2 ELISA Kit
 Killer cell lectin-like receptor subfamily G member 2 Recombinant
 Killer cell lectin-like receptor subfamily G member 2 Antibody
KLRG2: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral
 Klrg2 ELISA Kit
 Klrg2 Recombinant
 Klrg2 Antibody
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