Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Protein Family  rightarrow Kinase suppressor of Ras  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Glycidyl Palmitate Biochemical
 • SOX6 Antibody
 • SH3PXD2A - TKS5 Antibody
 • LAMA5 siRNA
 • DZIP1 Antibody
 • Brain Tissue Lysate Native Protein
 • Homeobox protein SIX3 (Six3) Recombinant Protein
 • Cell Division Cycle Protein 42 (CDC42) ELISA Kit
 • Extra Sense BCA Protein Assay Kit Assay Kit
 • Putative 5' (3')-deoxyribonucleotidase (CT1214) Recombinant Protein
 • Cell division protein FtsZ (ftsZ) Recombinant Protein
 • SOX9 Recombinant Protein
 • Cytochrome P450 1B1 (Cyp1b1) ELISA Kit
 • 1-(5-phosphoribosyl)-5-[ (5-phosphoribosylamino) methylidene... Recombinant Protein
 downarrow more ...
separator

Kinase suppressor of Ras

separator
Scaffolding protein that is part of a multiprotein signaling complex. Promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Does not have kinase activity by itself.

Below are the list of possible Kinase suppressor of Ras products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Kinase suppressor of Ras 1

 Kinase suppressor of Ras 1 ELISA Kit
 Kinase suppressor of Ras 1 Recombinant
 Kinase suppressor of Ras 1 Antibody
KSR: a serine/threonine kinase of the Raf family with no demonstrated kinase activity. A location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. Interacts with RAF and MAPK/ERK, in a Ras-dependent manner. The binding of 14-3-3 proteins to phosphorylated KSR prevents the membrane localizatio
>>>
n. In unstimulated cells, the phosphorylated form is bound to a 14-3-3 protein and sequestered in the cytoplasm. Translocates from the cytoplasm to the cell periphery following TNF treatment. When Bad is available, ceramide signaling through the Ras/Raf cascade can lead to apoptosis. Three alternatively-spliced isoforms have been described.

Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, TKL; RAF family; TKL group

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: cytosol; endoplasmic reticulum; membrane; protein complex

Molecular Function: MAP-kinase scaffold activity; protein binding; protein C-terminus binding; protein kinase activity; signal transducer activity

Biological Process: cAMP-mediated signaling; MAPKKK cascade; positive regulation of MAPKKK cascade; protein amino acid phosphorylation; Ras protein signal transduction
 KSR1 ELISA Kit
 KSR1 Recombinant
 KSR1 Antibody
 KSR ELISA Kit
 KSR Recombinant
 KSR Antibody
Table BarTOPTable Bar
 

Kinase suppressor of Ras 2

 Kinase suppressor of Ras 2 ELISA Kit
 Kinase suppressor of Ras 2 Recombinant
 Kinase suppressor of Ras 2 Antibody
KSR2: Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. 2 isoforms of the human protein are produced by alterna
>>>
tive splicing.

Protein type: EC 2.7.11.1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, TKL; RAF family; TKL group

Cellular Component: cytosol; plasma membrane

Molecular Function: MAP-kinase scaffold activity; mitogen-activated protein kinase kinase binding; protein binding

Biological Process: calcium-mediated signaling; positive regulation of MAPKKK cascade
 Ksr2 ELISA Kit
 Ksr2 Recombinant
 Ksr2 Antibody
Table BarTOPTable Bar
 

Kinase suppressor of Ras A

 Kinase suppressor of Ras A ELISA Kit
 Kinase suppressor of Ras A Recombinant
 Kinase suppressor of Ras A Antibody
Serine/threonine-protein kinase which positively regulates Ras-mediated signaling probably acting at the level of let-60/ras or/and lin-45/raf. Involved in sex myoblast migration (PubMed:8521513, PubMed:11882296). Plays a role in responses to M.nematophilum-mediated bacterial infection by promoting tail swelling and preventing constipation (PubMed:15268855). Functions redundantly with ksr-2 in the
>>>
Ras-mediated regulation of larval survival, the development of excretory canal and in mpk-1 phosphorylation in somatic cells (PubMed:8521513, PubMed:11882296). In addition, involved in determining vulval precursor cell fate during vulval induction independently of its kinase activity (PubMed:8521514, PubMed:8521513, PubMed:10409742, PubMed:11882296). Plays a role in egg-laying (PubMed:23900546).
 ksr-1 ELISA Kit
 ksr-1 Recombinant
 ksr-1 Antibody
 F13B9.5 ELISA Kit
 F13B9.5 Recombinant
 F13B9.5 Antibody
Table BarTOPTable Bar
 

Kinase suppressor of Ras B

 Kinase suppressor of Ras B ELISA Kit
 Kinase suppressor of Ras B Recombinant
 Kinase suppressor of Ras B Antibody
Probable inactive protein kinase which positively regulates Ras-mediated signaling probably acting at the level of let-60/ras or/and lin-45/raf. In the germline, regulates meiotic progression during oogenesis and mpk-1 (isoform b) phosphorylation. Functions redundantly with ksr-1 in the Ras-mediated regulation of larval survival, the development of excretory canal, in determining vulval precursor
>>>
cell fate during vulval induction and in mpk-1 phosphorylation in somatic cells.
 ksr-2 ELISA Kit
 ksr-2 Recombinant
 ksr-2 Antibody
 F58D5.4 ELISA Kit
 F58D5.4 Recombinant
 F58D5.4 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions