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Lethal(3)malignant brain tumor-like protein

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Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/HIST1H1E at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription (By similarity).

Below are the list of possible Lethal(3)malignant brain tumor-like protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Lethal(3)malignant brain tumor-like protein 1

 Lethal(3)malignant brain tumor-like protein 1 ELISA Kit
 Lethal(3)malignant brain tumor-like protein 1 Recombinant
 Lethal(3)malignant brain tumor-like protein 1 Antibody
Also known as Lethal(3)malignant brain tumor-like protein 1 (H-l(3)mbt) (H-l(3)mbt protein) (L(3)mbt-like) (L(3)mbt protein homolog).
Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/HIST1H1E at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K2
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0me2), leading to condense chromatin and repress transcription ().
 L3MBTL1 ELISA Kit
 L3MBTL1 Recombinant
 L3MBTL1 Antibody
 L3MBT ELISA Kit
 L3MBT Recombinant
 L3MBT Antibody
 L3MBTL ELISA Kit
 L3MBTL Recombinant
 L3MBTL Antibody
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Lethal(3)malignant brain tumor-like protein 2

 Lethal(3)malignant brain tumor-like protein 2 ELISA Kit
 Lethal(3)malignant brain tumor-like protein 2 Recombinant
 Lethal(3)malignant brain tumor-like protein 2 Antibody
Also known as Lethal(3)malignant brain tumor-like protein 2 (H-l(3)mbt-like protein 2) (L(3)mbt-like protein 2).
L3MBTL2: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it
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may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Histone-binding

Chromosomal Location of Human Ortholog: 22q13.31-q13.33

Cellular Component: nucleoplasm; nucleus

Molecular Function: histone binding; methylated histone residue binding; protein binding

Biological Process: protein sumoylation
 L3MBTL2 ELISA Kit
 L3MBTL2 Recombinant
 L3MBTL2 Antibody
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Lethal(3)malignant brain tumor-like protein 3

 Lethal(3)malignant brain tumor-like protein 3 ELISA Kit
 Lethal(3)malignant brain tumor-like protein 3 Recombinant
 Lethal(3)malignant brain tumor-like protein 3 Antibody
Also known as Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (MBT-1).
This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma. [provided by RefSeq, Oct 2016
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 L3MBTL3 ELISA Kit
 L3MBTL3 Recombinant
 L3MBTL3 Antibody
 KIAA1798 ELISA Kit
 KIAA1798 Recombinant
 KIAA1798 Antibody
 MBT1 ELISA Kit
 MBT1 Recombinant
 MBT1 Antibody
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Lethal(3)malignant brain tumor-like protein 4

 Lethal(3)malignant brain tumor-like protein 4 ELISA Kit
 Lethal(3)malignant brain tumor-like protein 4 Recombinant
 Lethal(3)malignant brain tumor-like protein 4 Antibody
Also known as Lethal(3)malignant brain tumor-like protein 4 (H-l(3)mbt-like protein 4) (L(3)mbt-like protein 4).
L3MBTL4: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. 2 isoforms of the human protein are produced by alternative splicing.
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Chromosomal Location of Human Ortholog: 18p11.31

Molecular Function: protein binding
 L3MBTL4 ELISA Kit
 L3MBTL4 Recombinant
 L3MBTL4 Antibody
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