Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Protein Family  rightarrow Lethal factor  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • CIKS (TRAF3IP2) Antibody
 • Donkey anti Rabbit IgG (H + L) (Cy3) Secondary Antibody
 • Chlamydia trachomatis MOMP Antibody
 • mannosidase, alpha, class 1A, member 1 (MAN1A1) ELISA Kit
 • Troponin I (TNNI3) Antibody
 • ADAMTS1 cDNA Clone
 • Vascular endothelial growth factor C (Vegfc) Antibody
 • ectonucleoside triphosphate diphosphohydrolase 3 (Entpd3) Antibody
 • Myoglobin, Bovine (MB) Protein
 • Phospholipase C (PLC) ELISA Kit
 • Anti nucleosome antibody IgG (AnuA IgG) ELISA Kit
 • NSUN2 Antibody
 • 5-Hydroxytryptophan (5-HTP) ELISA Kit
 downarrow more ...

Lethal factor

Below are the list of possible Lethal factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Lethal factor

 Lethal factor ELISA Kit
 Lethal factor Recombinant
 Lethal factor Antibody
Also known as Lethal factor (LF) (Anthrax lethal toxin endopeptidase component).
One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. LF is the lethal factor that, when associated with PA, causes death. LF is not toxic by itself. It is a protease that cleaves the N-terminal of most dual specificity mitogen-activated protein kinase kinases (MAPKKs or MAP2Ks) (except for MAP2K5). Cleavage invariably occurs within the N-terminal proline-rich region preceding the kinase domain, thus disrupting a sequence involved in dire
cting specific protein-protein interactions necessary for the assembly of signaling complexes. There may be other cytosolic targets of LF involved in cytotoxicity. The proteasome may mediate a toxic process initiated by LF in the cell cytosol involving degradation of unidentified molecules that are essential for macrophage homeostasis. This is an early step in LeTx intoxication, but it is downstream of the cleavage by LF of MEK1 or other putative substrates. Also cleaves mouse Nlrp1b allele 1, leading to NLRP1 inflammasome activation, IL1B release and eventually host inflammatory response (PubMed:19651869).
 lef ELISA Kit
 lef Recombinant
 lef Antibody
 pXO1-107 ELISA Kit
 pXO1-107 Recombinant
 pXO1-107 Antibody
 BXA0172 ELISA Kit
 BXA0172 Recombinant
 BXA0172 Antibody
 GBAA_pXO1_0172 ELISA Kit
 GBAA_pXO1_0172 Recombinant
 GBAA_pXO1_0172 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions