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Leucine-rich repeat-containing G-protein coupled receptor

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Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May play a role in regulating the circadian rhythms of plasma lipids (By similarity).

Below are the list of possible Leucine-rich repeat-containing G-protein coupled receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Leucine-rich repeat-containing G-protein coupled receptor 4

 Leucine-rich repeat-containing G-protein coupled receptor 4 ELISA Kit
 Leucine-rich repeat-containing G-protein coupled receptor 4 Recombinant
 Leucine-rich repeat-containing G-protein coupled receptor 4 Antibody
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to
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classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May play a role in regulating the circadian rhythms of plasma lipids ().
 lgr4 ELISA Kit
 lgr4 Recombinant
 lgr4 Antibody
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Leucine-rich repeat-containing G-protein coupled receptor 5

 Leucine-rich repeat-containing G-protein coupled receptor 5 ELISA Kit
 Leucine-rich repeat-containing G-protein coupled receptor 5 Recombinant
 Leucine-rich repeat-containing G-protein coupled receptor 5 Antibody
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression o
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f target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.
 lgr5 ELISA Kit
 lgr5 Recombinant
 lgr5 Antibody
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Leucine-rich repeat-containing G-protein coupled receptor 5A

 Leucine-rich repeat-containing G-protein coupled receptor 5A ELISA Kit
 Leucine-rich repeat-containing G-protein coupled receptor 5A Recombinant
 Leucine-rich repeat-containing G-protein coupled receptor 5A Antibody
Also known as Leucine-rich repeat-containing G-protein coupled receptor 5A (LGR5a).
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular
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Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development ().
 lgr5-a ELISA Kit
 lgr5-a Recombinant
 lgr5-a Antibody
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Leucine-rich repeat-containing G-protein coupled receptor 6

 Leucine-rich repeat-containing G-protein coupled receptor 6 ELISA Kit
 Leucine-rich repeat-containing G-protein coupled receptor 6 Recombinant
 Leucine-rich repeat-containing G-protein coupled receptor 6 Antibody
LGR6: a leucine-rich repeat-containing G-protein-coupled receptor. Receptor for R-spondins, potent stimulators of adult stem cell proliferation. A marker of adult stem cells. A Wnt receptor component that enhances Wnt signaling by soluble R-spondin proteins. A marker of a multipotent population of skin stem cells. Three isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; Tumor suppressor

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: i
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ntegral to plasma membrane; plasma membrane; trans-Golgi network membrane; vesicle

Molecular Function: G-protein coupled receptor activity; protein binding; transmembrane receptor activity

Biological Process: positive regulation of cell migration; positive regulation of Wnt receptor signaling pathway
 LGR6 ELISA Kit
 LGR6 Recombinant
 LGR6 Antibody
 UNQ6427/PRO21331 ELISA Kit
 UNQ6427/PRO21331 Recombinant
 UNQ6427/PRO21331 Antibody
 VTS20631 ELISA Kit
 VTS20631 Recombinant
 VTS20631 Antibody
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