| Leukocyte immunoglobulin-like receptor subfamily B member 2 ELISA Kit|
Leukocyte immunoglobulin-like receptor subfamily B member 2 Recombinant
Leukocyte immunoglobulin-like receptor subfamily B member 2 Antibody
|Also known as Leukocyte immunoglobulin-like receptor subfamily B member 2 (LIR-2) (Leukocyte immunoglobulin-like receptor 2) (CD85 antigen-like family member D) (Immunoglobulin-like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD antigen CD85d). |
LILRB2: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular
proteins and mobilization of intracellular calcium ions. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 19q13.4
Cellular Component: cell surface; cytoplasm; extracellular space; integral to plasma membrane; membrane; plasma membrane
Molecular Function: cell adhesion molecule binding; inhibitory MHC class I receptor activity; MHC class I protein binding; protein binding; protein phosphatase 1 binding; receptor activity
Biological Process: cell surface receptor linked signal transduction; cell-cell signaling; cellular defense response; Fc receptor mediated inhibitory signaling pathway; heterotypic cell-cell adhesion; immune response; immune response-inhibiting cell surface receptor signaling pathway; negative regulation of antigen processing and presentation; negative regulation of calcium ion transport; negative regulation of immune response; negative regulation of T cell proliferation; positive regulation of regulatory T cell differentiation; positive regulation of T cell proliferation; positive regulation of T cell tolerance induction; positive regulation of tolerance induction; regulation of immune response; signal transduction
| LILRB2 ELISA Kit|
| ILT4 ELISA Kit|
| LIR2 ELISA Kit|
| MIR10 ELISA Kit|